Sameer Walavalkar - Los Angeles CA, US Axel Scherer - Woodstock VT, US Thomas A. Tombrello - Altadena CA, US Aditya Rajagopal - Irvine CA, US Andrew P. Homyk - South Pasadena CA, US Erika Garcia - Los Angeles CA, US
Methods and devices for sequencing nucleic acids are disclosed herein. Devices are also provided herein for measuring DNA with nano-pores sized to allow DNA to pass through the nano-pore. The capacitance can be measured for the DNA molecule passing through the nano-pore. The capacitance measurements can be correlated to determine the sequence of base pairs passing through the nano-pore to sequence the DNA.
Optical Technique For Chemical And Biochemical Analysis
Xiomara L. MADERO - GLENDALE CA, US Erika F. GARCIA - LOS ANGELES CA, US Axel SCHERER - BARNARD VT, US
International Classification:
G01N 21/64
US Classification:
356432
Abstract:
Structures and methods are described for optical detection of physical, chemical and/or biological samples. An optical detection structure may include a LED source, multiple filters and single or multiple sample areas. A detector may be used to record a fluorescence signal. The sample area may allow the introduction of removable cartridges.
Multiplexing And Quantification In Pcr With Reduced Hardware And Requirements
Xiomara Linnette MADERO - Glendale CA, US Erika F. GARCIA - Los Angeles CA, US Sheel Mukesh SHAH - Los Angeles CA, US Axel SCHERER - Barnard VT, US
Assignee:
CALIFORNIA INSTITUTE OF TECHNOLOGY - Pasadena CA
International Classification:
G01N 21/64
US Classification:
435 612, 4352872
Abstract:
Methods and algorithms for a multiplexed single detection channel amplification process and quantification of generated amplicons is presented. Various mathematical approaches for quantifying and verifying the amplicons in a reaction are presented. Usage of such methods and approaches allow upgrading of existing single and multiple channel instruments for further multiplexing capabilities.
Devices And Methods For Biological Sample Preparation
Erika F GARCIA - Los Angeles CA, US Xiomara Linnette MADERO - Glendale CA, US Axel SCHERER - Barnard VT, US
Assignee:
California Institute Of Technology - Pasadena CA
International Classification:
C12N 15/10
US Classification:
435 612, 4353061, 435 792
Abstract:
Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers.
Pen-Shaped Device For Biological Sample Preparation And Analysis
Imran R MALIK - Pasadena CA, US Erika F GARCIA - Los Angeles CA, US Axel SCHERER - Barnard VT, US
Assignee:
California Institute Of Technology - Pasadena CA
International Classification:
C12N 15/10
US Classification:
435 612, 4353061, 435 792, 137561 R
Abstract:
Methods and devices for biological sample preparation and analysis are disclosed. A device may have a circular arrangement of containers, with a connecting structure such as a disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. The device may be pen-shaped and have a sample drawing needle connected to the containers.
Devices And Methods For Biological Sample-To-Answer And Analysis
Erika F. GARCIA - Los Angeles CA, US Xiomara Linnette MADERO - Glendale CA, US Axel SCHERER - Barnard VT, US
Assignee:
California Institute Of Technology - Pasadena CA
International Classification:
C12Q 1/68
US Classification:
435 612, 4352872
Abstract:
Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers. The device may have a reaction cartridge with a reaction chamber to perform techniques such as polymerase chain reaction.
Multiplexing And Quantification In Pcr With Reduced Hardware And Requirements
- Pasadena CA, US Xiomara Linnette MADERO - Glendale CA, US Erika F. GARCIA - Los Angeles CA, US Sheel Mukesh SHAH - Los Angeles CA, US Axel SCHERER - Barnard VT, US
International Classification:
G01N 21/64 C12Q 1/68
Abstract:
Methods and algorithms for a multiplexed single detection channel amplification process and quantification of generated amplicons is presented. Various mathematical approaches for quantifying and verifying the amplicons in a reaction are presented. Usage of such methods and approaches allow upgrading of existing single and multiple channel instruments for further multiplexing capabilities.
Instruments For Biological Sample Preparation Devices
- PASADENA CA, US Erika F. GARCIA - LOS ANGELES CA, US Xiomara Linnette MADERO - GLENDALE CA, US Axel SCHERER - BARNARD VT, US
Assignee:
CALIFORNIA INSTITUTE OF TECHNOLOGY - PASADENA CA
International Classification:
C12Q 1/68
US Classification:
4352862, 4352831, 4352861
Abstract:
Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers.
Sage Family Medicine Associates 524 E Nopal St, Uvalde, TX 78801 (830)2784588 (phone), (830)2784895 (fax)
Education:
Medical School Baylor College of Medicine Graduated: 2011
Procedures:
Lumbar Puncture
Conditions:
Diabetes Mellitus (DM) Hypertension (HTN)
Languages:
English Spanish
Description:
Dr. Garcia graduated from the Baylor College of Medicine in 2011. She works in Uvalde, TX and specializes in Family Medicine. Dr. Garcia is affiliated with Uvalde Memorial Hospital.
Dr. Garcia graduated from the University of New Mexico School of Medicine in 2008. She works in Portales, NM and specializes in Family Medicine. Dr. Garcia is affiliated with Roosevelt General Hospital.
"We all have known since the beginning of the pandemic when numbers were coming up that there were differential impacts for different groups and we saw that especially for Black and Hispanic individuals," said Erika Garcia, an assistant professor of preventive medicine at the Keck School of Medicine