Eugene B Buynak from 244 Stefan Pl, North Wales, PA 19454, Phone: (215)6995624

Method For Purifying Hepatitis B Antigen
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US Patent:

40173607, Apr 12, 1977
Filed:

May 14, 1975
Appl. No.:

5/577483
Inventors:

Alexander U. Bertland - Lansdale PA
Alfred A. Tytell - Lansdale PA
George P. Lampson - Hatfield PA
Eugene Buynak - North Wales PA
Assignee:

Merck & Co., Inc. - Rahway NJ
International Classification:

A61K 3912
C12K 500
C12K 700
US Classification:

195 14
Abstract:

Hepatitis B antigen useful as vaccine is prepared from clarified plasma of hepatitis B donors by treating with pepsin at a pH wherein pepsin is enzymatically active, treating with urea, and optionally treating with formaldehyde.

Varicella Vaccine And Process For Its Preparation
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US Patent:

40002560, Dec 28, 1976
Filed:

Jul 2, 1975
Appl. No.:

5/592562
Inventors:

Maurice R. Hilleman - Lafayette Hill PA
Eugene B. Buynak - North Wales PA
Beverly J. Neff - Harleysville PA
Assignee:

Merck & Co., Inc. - Rahway NJ
International Classification:

A61K 3912
C12K 500
C12K 700
US Classification:

424 89
Abstract:

Preparation of safe, live, attenuated varicella virus vaccine by serial propagation of varicella virus in tissue cell culture systems.

Parainfluenza Virus Vaccine And Its Preparation
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US Patent:

42151074, Jul 29, 1980
Filed:

Dec 29, 1978
Appl. No.:

5/974396
Inventors:

Eugene B. Buynak - North Wales PA
Maurice R. Hilleman - Lafayette Hill PA
Assignee:

Merck & Co., Inc. - Rahway NJ
International Classification:

A61K 3912
US Classification:

424 89
Abstract:

By serially passaging virulent parainfluenza virus in tissue culture prepared from embryonated hens' eggs or human diploid lung fibroblasts, a live, non-pathogenic but antigenic live parainfluenza virus is produced. This virus is useful in preparing a live virus vaccine.

Respiratory Syncytial Vaccine
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US Patent:

41452526, Mar 20, 1979
Filed:

Jun 26, 1978
Appl. No.:

5/918760
Inventors:

Eugene B. Buynak - North Wales PA
Maurice R. Hilleman - Lafayette Hill PA
Assignee:

Merck & Co., Inc. - Rahway NJ
International Classification:

C12K 700
US Classification:

195 13
Abstract:

By serially passaging virulent respiratory syncytial virus in human diploid lung fibroblasts, a non-pathogenic but antigenic live respiratory syncytial virus is produced. This virus is useful in preparing a live virus vaccine.

Respiratory Synctial Vaccine
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US Patent:

41221672, Oct 24, 1978
Filed:

Aug 17, 1977
Appl. No.:

5/825520
Inventors:

Eugene B. Buynak - North Wales PA
Maurice R. Hilleman - Lafayette Hill PA
Assignee:

Merck & Co., Inc. - Rahway NJ
International Classification:

A61K 3912
C12B 300
US Classification:

424 89
Abstract:

By serially passaging virulent respiratory syncytial virus in human diploid lung fibroblasts, a non-pathogenic but antigenic live respiratory syncytial virus is produced. This virus is useful in preparing a live virus vaccine.

Eugene B Buynak