Eugene Schaefer from Bangor, PA, age 68

Compositions And Methods For Producing A Composition
view source
US Patent:

20210246188, Aug 12, 2021
Filed:

Nov 25, 2020
Appl. No.:

17/105358
Inventors:

- Princeton NJ, US
Eugene J. Schaefer - Westfield NJ, US
Ronald Charles Bates - Irvine CA, US
Elizabeth A. Bramhall - Groton MA, US
David Michael Didio - Syracuse NY, US
Robert Donaldson - Southborough MA, US
Alan R. Flesher - Lawrenceville NJ, US
Helen Gray Haggerty - Manlius NY, US
David Henry Kirkley - East Syracuse NY, US
John Malcolm Tabor - Syracuse NY, US
Lee K. Tay - Princeton Junction NJ, US
Pallaiah Thammana - Manlius NY, US
Ajoy Velayudhan - Cary NC, US
David Edward Smolin - Pennington NJ, US
Reb J. Russell - Doylestown PA, US
Thomas James Vanden Boom - Flemington NJ, US
Dean Woodrow Brownell - Oswego NY, US
Jeffrey Schrimsher - Hillsborough NC, US
Joyce Patricia Whitehead - Manlius NY, US
Assignee:

Bristol-Myers Squibb Company - Princeton NJ
International Classification:

C07K 14/705
A61K 38/19
C07K 16/28
Abstract:

The invention provides for mammalian cells capable of producing recombinant CTLA4-Ig and variants thereof. The invention also provides for compositions comprising CTLA4-Ig and formulations thereof. The invention further provides for methods for mass-producing CTLA4-Ig from mammalian cells capable of producing this recombinant protein, and for purifying the CTLA4-Ig.

Carbohydrate Content Of Ctla4 Molecules
view source
US Patent:

20200017569, Jan 16, 2020
Filed:

Jul 24, 2018
Appl. No.:

16/044252
Inventors:

- Princeton NJ, US
Eugene J. Schaefer - Westfield NJ, US
Ronald Charles Bates - Irvine CA, US
Elizabeth A. Bramhall - Groton MA, US
David Michael Didio - Syracuse NY, US
Robert Donaldson - Southborough MA, US
Alan R. Flesher - Lawrenceville NJ, US
Helen Gray Haggerty - Manlius NY, US
David Henry Kirkley - East Syracuse NY, US
John Malcolm Tabor - Syracuse NY, US
Lee K. Tay - Princeton Junction NJ, US
Pallaiah Thammana - Manlius NY, US
Ajoy Velayudhan - Cary NC, US
David Edward Smolin - Pennington NJ, US
Reb J. Russell - Doylestown PA, US
Thomas James Vanden Boom - Flemington NJ, US
Dean Woodrow Brownell - Oswego NY, US
Jeffrey Schrimsher - Hillsborough NC, US
Joyce Patricia Whitehead - Manlius NY, US
International Classification:

C07K 14/705
A61K 38/19
C07K 16/28
A61K 38/00
B01D 15/38
Abstract:

The invention provides for mammalian cells capable of producing recombinant CTLA4-Ig and variants thereof. The invention also provides for compositions comprising CTLA4-Ig and formulations thereof The invention further provides for methods for mass-producing CTLA4-Ig from mammalian cells capable of producing this recombinant protein, and for purifying the CTLA4-Ig.

Compositions And Methods For Producing A Composition
view source
US Patent:

20190092835, Mar 28, 2019
Filed:

Jul 24, 2018
Appl. No.:

16/044217
Inventors:

- Princeton NJ, US
Eugene J. Schaefer - Westfield NJ, US
Ronald Charles Bates - Irvine CA, US
Elizabeth A. Bramhall - Groton MA, US
David Michael Didio - Syracuse NY, US
Robert Donaldson - Southborough MA, US
Alan R. Flesher - Lawrenceville NJ, US
Helen Gray Haggerty - Manlius NY, US
David Henry Kirkley - East Syracuse NY, US
John Malcolm Tabor - Syracuse NY, US
Lee K. Tay - Princeton Junction NJ, US
Pallaiah Thammana - Manlius NY, US
Ajoy Velayudhan - Cary NC, US
David Edward Smolin - Pennington NJ, US
Reb J. Russell - Doylestown PA, US
Thomas James Vanden Boom - Flemington NJ, US
Dean Woodrow Brownell - Oswego NY, US
Jeffrey Schrimsher - Hillsborough NC, US
Joyce Patricia Whitehead - Manlius NY, US
International Classification:

C07K 14/705
C07K 16/28
A61K 38/19
A61K 38/00
B01D 15/38
Abstract:

The invention provides for mammalian cells capable of producing recombinant CTLA4-Ig and variants thereof. The invention also provides for compositions comprising CTLA4-Ig and formulations thereof. The invention further provides for methods for mass-producing CTLA4-Ig from mammalian cells capable of producing this recombinant protein, and for purifying the CTLA4-Ig.

Carbohydrate Content Of Ctla4 Molecules
view source
US Patent:

20190062399, Feb 28, 2019
Filed:

Jul 23, 2018
Appl. No.:

16/042977
Inventors:

- Princeton NJ, US
Eugene J. Schaefer - Westfield NJ, US
Ronald Charles Bates - Irvine CA, US
Elizabeth A. Bramhall - Groton MA, US
David Michael Didio - Syracuse NY, US
Robert Donaldson - Southborough MA, US
Alan R. Flesher - Lawrenceville NJ, US
Helen Gray Haggerty - Manlius NY, US
David Henry Kirkley - East Syracuse NY, US
John Malcolm Tabor - Syracuse NY, US
Lee K. Tay - Princeton Junction NJ, US
Pallaiah Thammana - Manlius NY, US
Ajoy Velayudhan - Cary NC, US
David Edward Smolin - Pennington NJ, US
Reb J. Russell - Doylestown PA, US
Thomas James Vanden Boom - Flemington NJ, US
Dean Woodrow Brownell - Oswego NY, US
Jeffrey Schrimsher - Hillsborough NC, US
Joyce Patricia Whitehead - Manlius NY, US
International Classification:

C07K 14/705
C07K 16/28
A61K 38/19
A61K 38/00
B01D 15/38
Abstract:

The invention provides for mammalian cells capable of producing recombinant CTLA4-Ig and variants thereof. The invention also provides for compositions comprising CTLA4-Ig and formulations thereof. The invention further provides for methods for mass-producing CTLA4-Ig from mammalian cells capable of producing this recombinant protein, and for purifying the CTLA4-Ig.