Eun H Lee

US Patent:

7074561, Jul 11, 2006

Filed:

Oct 22, 2002

Appl. No.:

10/277645

Inventors:

Roxanne N. Shurtliff - Herndon VA, US
Eun Mi Lee - Rockville MD, US

Assignee:

bioMerieux, Inc. - Durham NC

International Classification:

C12Q 1/68
C12P 19/34
C07H 21/04

US Classification:

435 6, 435 912, 435810, 536 221, 536 243

Abstract:

The present invention is directed to isothermal transcription based assays for the detection and quantification of alpha-fetoprotein (AFP) mRNA. The present invention is also directed to oligonucleotides for amplifying AFP mRNA and probes for use in the detection and quantification of the amplification product. The present invention is also directed to detecting hepatocellular carcinoma, metastasis thereof and tumor recurrence by analyzing peripheral blood for the presence of AFP mRNA.

US Patent:

20030199472, Oct 23, 2003

Filed:

Mar 19, 2003

Appl. No.:

10/392274

Inventors:

Eun Lee - Northbrook IL, US
J. Jameson - Winnetka IL, US

International Classification:

C12Q001/68
A61K048/00

US Classification:

514/044000, 435/006000

Abstract:

The present invention provides methods of treating and preventing uterine fibroids that is non-surgical, using a modified estrogen receptor gene delivered via an adenoviral vector. The modified estrogen receptor induced apoptosis in vitro and decreased tumor growth in vivo. The invention provides a major improvement above that of current available procedures for women having uterine fibroids, or in preventing fibroids in women at risk of having fibroids. The present invention further provides a safe means of treating fibroids and preserving fertility in young women, or maintaining pregnancy in pregnant women having fibroids.

US Patent:

20040018494, Jan 29, 2004

Filed:

Jul 25, 2002

Appl. No.:

10/202639

Inventors:

Roxanne Shurtliff - Herndon VA, US
Eun Lee - Rockville MD, US
Joseph Romano - Wayne PA, US

International Classification:

C12Q001/68
C07H021/02

US Classification:

435/006000, 536/023100

Abstract:

The present invention is directed to an isothermal transcription based assay for the detection and quantification of guanylyl cyclase C (GCC). The present invention is also directed to oligonucleotides for amplifying GCC RNA and probes for use in the detection and quantification of the amplification product. Finally, the present invention is directed to a method for detecting colon carcinoma, micrometastasis thereof and tumor recurrence by analyzing peripheral blood for the presence of GCC.

US Patent:

61875678, Feb 13, 2001

Filed:

Sep 1, 1999

Appl. No.:

9/387455

Inventors:

Yuexia Li - Burtonsville MD
Kathy Lynn Hickman - Germantown MD
Eun Mi Lee - Gaithersburg MD
Gregory John Hurteau - Clifton Park NY

Assignee:

Akzo Nobel N.V. - Arnhem

International Classification:

C12P 1934

US Classification:

435 912

Abstract:

The present invention provides in situ amplification methods for the detection of a target nucleic acid molecule. The methods use a molecule termed "molecular tape" to retain the amplified target nucleic acid molecule within a cell upon amplification. The molecular tape, which may be used with a variety of amplification methods, improves the in situ detection of an amplified target molecule.

US Patent:

63331500, Dec 25, 2001

Filed:

Aug 13, 1999

Appl. No.:

9/374584

Inventors:

Joseph W. Romano - Derwood MD
Eun Mi Lee - Gaithersburg MD
Gregory J. Hurteau - Alexandria VA

Assignee:

Akzo Nobel N.V.

International Classification:

C12Q 170
C12Q 168
C07H 2102
C07H 2104
C12N 1500

US Classification:

435 5

Abstract:

An isothermal transcription based amplification assay for dengue virus RNA uses primer combinations for sequences within the envelope gene or the 3' non-coding region of the virus and a probe. Probes may be specific for a serotype of dengue virus.

US Patent:

59687320, Oct 19, 1999

Filed:

Dec 31, 1997

Appl. No.:

9/002177

Inventors:

Joseph W. Romano - Derwood MD
Eun Mi Lee - Gaithersburg MD
Gregory J. Hurteau - Alexandria VA

Assignee:

Akzo Nobel, N.V. - Arnhem

International Classification:

C12Q 170
C12Q 168
C07H 2104

US Classification:

435 5

Abstract:

An isothermal transcription based amplification assay for dengue virus RNA uses primer combinations for sequences within the envelope gene or the 3' non-coding region of the virus and a probe. Probes may be specific for a serotype of dengue virus.

US Patent:

62040243, Mar 20, 2001

Filed:

Sep 12, 1997

Appl. No.:

8/928465

Inventors:

Joseph W. Romano - Derwood MD
Eun Mi Lee - Laurel MD

Assignee:

Akzo Nobel N.V. - Arnhem

International Classification:

C12Q 168
C12P 1934
C07H 2104
C07H 2100

US Classification:

435 911

Abstract:

A method and a test kit for genotyping the CCR5 chemokine receptor. CCR5 transcript DNA is amplified using transcription based amplification. The amplification product is detected through the hybridization of appropriately labeled oligonucleotide wild type and mutant probes. In a liquid hybridization based ECL analysis, the mutant probe is a 16mer having the sequence 5'TCCATACATTAAAGAT3' [SEQ ID NO:9]. The method and kit can be used to predict.

US Patent:

20150050522, Feb 19, 2015

Filed:

Aug 14, 2013

Appl. No.:

13/967129

Inventors:

Arumugam Manthiram - Austin TX, US
Eun Sung Lee - Austin TX, US

International Classification:

H01M 4/131

US Classification:

429 7, 429223

Abstract:

The present disclosure relates to an electrochemically active lithium-rich layered oxide having the general formula LiMnNiMO, wherein M is cobalt (Co), chromium (Cr), or any combinations thereof, wherein, with respect to the amount of Li, 1

Address:

4044 Timber Oak Trl, Fairfax, VA 22033

VIN:

5FNRL386X7B080878

Make:

HONDA

Model:

ODYSSEY

Year:

2007

Address:

8237 Glade Bank Dr, Manassas, VA 20111

VIN:

KNDMC233576017135

Make:

HYUNDAI

Model:

ENTOURAGE

Year:

2007

Address:

13509 Shawna Dnay Dr, Austin, TX 78727

VIN:

KM8JN72D87U480575

Make:

HYUNDAI

Model:

TUCSON

Year:

2007