Eva B Chan

US Patent:

6617102, Sep 9, 2003

Filed:

Oct 25, 2000

Appl. No.:

09/696668

Inventors:

Ying Luo - Los Altos CA
Eva Chan - San Francisco CA
Xiang Xu - San Francisco CA
Betty Huang - San Leandro CA
Valeria Ossovskaya - Sausalito CA

Assignee:

Rigel Pharmaceuticals, Inc. - South San Francisco CA

International Classification:

C12Q 100

US Classification:

435 4, 435 6, 435 71

Abstract:

The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.

US Patent:

6887675, May 3, 2005

Filed:

Apr 25, 2001

Appl. No.:

09/843159

Inventors:

Ying Luo - Los Altos CA, US
Eva Chan - Foster City CA, US
Xiang Xu - South San Francisco CA, US
Betty Huang - San Leandro CA, US
Valeria Ossovskaya - Sausalito CA, US

Assignee:

Rigel Pharmaceuticals, Inc. - South San Francisco CA

International Classification:

C12N009/12
C12N009/16
C12O001/44
C12O001/48
C07H021/04

US Classification:

435 19, 435 4, 435 6, 435 15, 435 691, 435183, 435194, 435196, 4352523, 4353201, 536 232, 536 234, 536 235, 530350

Abstract:

The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.

US Patent:

20050074825, Apr 7, 2005

Filed:

Jul 8, 2003

Appl. No.:

10/616101

Inventors:

Ying Luo - Pudong New Area, CN
Eva Chan - Belmont CA, US
Xiang Xu - South San Francisco CA, US
Betty Huang - San Leandro CA, US
Valeria Ossovskaya - San Francisco CA, US

International Classification:

G01N033/574

US Classification:

435007230

Abstract:

The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.

US Patent:

20110126309, May 26, 2011

Filed:

Oct 22, 2010

Appl. No.:

12/910478

Inventors:

David Caldwell - St Louis MO, US
Eva Chan - Davis CA, US
Jeroen de Vries - Den Haag, NL
Tarek Joobeur - Sacramento CA, US
Joseph King - Davis CA, US
Antonio Reina - Almeria, ES
Nischit Shetty - Ft. Myers FL, US

International Classification:

A01H 1/04
A01H 5/00
C07H 21/04
C12N 5/04

US Classification:

800267, 800307, 536 243, 435410

Abstract:

The present invention relates to methods for identifying cucumber lines having increased resistance to Downy Mildew, and identification of genetic markers linked to gene(s) conditioning such increased disease resistance. The present invention also relates to methods of breeding cucumber plants from lines having increased Downy Mildew resistance by marker-assisted selection, compositions including nucleic acid probes or primers which are useful for such marker assisted selection, and plants and plant parts produced by such methods.

US Patent:

6589725, Jul 8, 2003

Filed:

Oct 25, 1999

Appl. No.:

09/427154

Inventors:

Ying Luo - Los Altos CA
Eva Chan - San Francisco CA
Xiang Xu - South San Francisco CA
Betty Huang - San Leandro CA

Assignee:

Rigel Pharmaceuticals, Inc. - South San Francisco CA

International Classification:

C12Q 100

US Classification:

435 4, 435 6, 435 691

Abstract:

The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.

US Patent:

20230034185, Feb 2, 2023

Filed:

Jun 30, 2022

Appl. No.:

17/855475

Inventors:

- St. Louis MO, US
Eva King-Fan Chan - Davis CA, US
Jeneylyne Ferrera Colcol - St. Louis MO, US
Richard Jones - St. Louis MO, US
Chad Kramer - Winters CA, US
Wenwen Xiang - St. Louis MO, US

International Classification:

A01H 1/04
C12Q 1/6895
C12N 15/82
A01H 6/04

Abstract:

The present disclosure provides for unique onion plants with disease resistance and desirable bulb color and their progeny. Such plants may comprise an introgressed QTL associated with multiple disease resistance coupled with a desirable bulb color. In certain aspects, compositions, including distinct polymorphic molecular markers, and methods for producing, breeding, identifying, selecting, and the like of plants or germplasm with disease resistance and/or desirable bulb color are provided.

US Patent:

20150150155, May 28, 2015

Filed:

Nov 21, 2014

Appl. No.:

14/550705

Inventors:

- St. Louis MO, US
Eva King-Fan Chan - Davis CA, US
Jeneylyne Ferrera Colcol - St. Louis MO, US
Richard Jones - St. Louis MO, US
Chad Kramer - Winters CA, US
Wenwen Xiang - St. Louis MO, US

International Classification:

C12N 15/82
C12Q 1/68

US Classification:

800265, 435 611, 435419, 800266, 800301

Abstract:

The present disclosure provides for unique onion plants with disease resistance and desirable bulb color and their progeny. Such plants may comprise an introgressed QTL associated with multiple disease resistance coupled with a desirable bulb color. In certain aspects, compositions, including distinct polymorphic molecular markers, and methods for producing, breeding, identifying, selecting, and the like of plants or germplasm with disease resistance and/or desirable bulb color are provided.