Complete Healthcare Communications - Chadds Ford, PA since Jul 2012
Medical Writer
Venenum BioDesign, LLC - Hamilton, NJ Jun 2011 - Jul 2012
Research Scientist
University of Pennsylvania Jan 2009 - Jun 2011
RESEARCH ASSOCIATE
Fox Chase Cancer Center Sep 2005 - Jun 2009
POSTDOCTORAL FELLOW
Umea Center for Molecular Medicine Sep 1999 - Jan 2005
PhD student
Education:
Umea University 1999 - 2005
PhD, Molecular Biology
Umea University 1999 - 2004
Master, Molecular Biology
Skills:
Molecular Biology Cell Biology Cell Biochemistry Tissue Culture Western Blotting Cancer Cancer Research Animal Models Stem Cells High Throughput Screening Science Cell Culture Qpcr Oncology Laboratory Transfection Drug Discovery Immunology Pcr Developmental Biology Immunofluorescence Molecular Cloning Biomarker Discovery Microarray Immunohistochemistry Medical Writing Hematology Hepatology Cell Based Assays
Aug 2013 to 2000 Scientific Communications ManagerComplete Healthcare Communications
2012 to Jul 2013 MEDICAL WRITERVenenum Biodesign Hamilton, NJ 2011 to 2012 RESEARCH SCIENTIST, TARGET BIOLOGY, CANCER SIGNALING AND CELL CYCLEUniversity of Pennsylvania Philadelphia, PA Jun 2009 to Jun 2011 Research AssociateFox Chase Cancer Center Philadelphia, PA 2005 to 2009 POSTDOCTORAL FELLOW, STEM CELL AND EPIGENETIC PROGRAMUmea University Ume 1999 to 2005 PHD STUDENT, UMEA CENTER FOR MOLECULAR MEDICINEUmea University Ume 1997 to 1999 Rotation student, Department of Neurobiology and OncologyAlphaBioCom
Medical writer
Education:
FOX CHASE CANCER CENTER - Philadelphia, PA 2005 to 2009 Postdoctoral studies in in Stem Cell Biology and EpigeneticsUMEA UNIVERSITY, Umea Center for Molecular Medicine Ume 1999 to 2004 PhD in Molecular BiologyUMEA UNIVERSITY, Depatment of Oncology Ume 1997 to 1998 Master in Molecular Biology/Oncology
2011 to 2000 RESEARCH SCIENTIST, TARGET BIOLOGY, CANCER SIGNALING AND CELL CYCLEUniversity of Pennsylavnia Philadelphia, PA 2009 to 2011 Research AssociateFox Chase Cancer Center Philadelphia, PA 2005 to 2009 Postdoctoral Fellow
Education:
University of Pennsylvania Philadelphia, PA Jan 2009 to Jan 2011 Post-doctoctoral in Cell and Developmental BiologyUmea University Ume Jan 1999 to Jan 2004 Ph.D. in Molecular Biology, Stem Cell Biology, Hematology, HepatologyUMEA UNIVERSITY, Umea, Sweden Jan 1997 Master in Molecular Biology, Cancer Biology
Skills:
Molecular Biology, Stem Cell Biology, Cancer Biology, Biochemistry, Developmental Biology, Mice, Science writing and editing
Us Patents
Pme-1 As A Biomarker To Predict And Diagnose An Increased Risk Of Endometrial Cancer And Gene Silencing Of Pme-1 To Inhibit Epithelial To Mesenchymal Transition
- Hamilton NJ, US Michelle Pusey - Bordentown NJ, US Ewa Wandzioch - Wyndmoor PA, US Sophie Marie Genevieve Bail - Princeton NJ, US Amy Lynn Wenda - North Brunswick NJ, US
Assignee:
Medical Diagnostic Laboratories, L.L.C. - Hamilton NJ
International Classification:
C12N 15/113 C12Q 1/68
Abstract:
Disclosed are methods of attenuating activity of the PME-1 gene. siRNAs or shRNAs are used to target against PME-1, thereby reducing the PME-1 mRNA. It is disclosed that the siRNAs or shRNAs targeted against PME-1 attenuate the epithelial to mesenchymal transition, thereby inhibit endometrial cancer development. A kit containing siRNA or shRNA reagents for attenuating the PME-1 gene expression is also disclosed.
Pme-1 As A Biomarker To Predict And Diagnose An Increased Risk Of Endometrial Cancer And Gene Silencing Of Pme-1 To Inhibit Epithelial To Mesenchymal Transition
Lyndi Rice - Philadelphia PA, US Michelle Pusey - Bordentown NJ, US Ewa Wandzioch - Wyndmoor PA, US
Assignee:
MEDICAL DIAGNOSTIC LABORATORIES, LLC - Hamilton NJ
International Classification:
C12Q 1/68 G01N 33/574 C12N 15/113
US Classification:
514 44 A, 435 71, 435 792, 435 612, 435375
Abstract:
Disclosed are methods of attenuating activity of the PME-1 gene. siRNAs or shRNAs are used to target against PME-1, thereby reducing the PME-1 mRNA. It is disclosed that the siRNAs or shRNAs targeted against PME-1 attenuate the epithelial to mesenchymal transition, thereby inhibit endometrial cancer development. A kit containing siRNA or shRNA reagents for attenuating the PME-1 gene expression is also disclosed.
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