Andrew J. MURPHY - Croton-on-Hudson NY, US Cagan GURER - Valhalla NY, US John MCWHIRTER - Tarrytown NY, US Vera VORONINA - Thornwood NY, US Faith HARRIS - Mamaroneck NY, US Sean STEVENS - San Francisco CA, US Yingzi XUE - Ardsley NY, US
Assignee:
REGENERON PHARMACEUTICALS, INC. - Tarrytown NY
International Classification:
A01K 67/027
US Classification:
800 18, 800 14, 536 234
Abstract:
The invention provides genetically modified non-human animals that express chimeric human/non-human MHC I polypeptide and/or human or humanized β2 microglobulin polypeptide, as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same. Methods of using the genetically modified animals to study various aspects of human immune system are provided.
Genetically Modified Major Histocompatibility Complex Mice
Andrew J. MURPHY - Croton-on-Hudson NY, US Cagan GURER - Valhalla NY, US John MCWHIRTER - Tarrytown NY, US Vera VORONINA - Thornwood NY, US Faith HARRIS - Mamaroneck NY, US Sean STEVENS - San Francisco CA, US
Assignee:
REGENERON PHARMACEUTICALS, INC. - Tarrytown NY
International Classification:
A01K 67/027 A01K 67/02 C12N 15/06
US Classification:
800 18, 800 14, 800 21, 800 22
Abstract:
The invention provides genetically modified non-human animals that express chimeric human/non-human MHC I polypeptide and/or human or humanized β2 microglobulin polypeptide, as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same. Methods of using the genetically modified animals to study various aspects of human immune system are provided.
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Faith Harris
Work:
Looking - Theology/Ethics Instructor
Education:
Virginia Union University - Theology Doctor of Ministry, Boston University - Practical Theology and Ethics, Moody Bible Institute - International Ministries, Virginia Union University - Master of Divinity