Felice Chu Lightstone from Mercer Island, WA, age 56

Tricyclic Gyrase Inhibitors
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US Patent:

20120238751, Sep 20, 2012
Filed:

Mar 14, 2012
Appl. No.:

13/496188
Inventors:

Daniel Bensen - Carlsbad CA, US
Zhiyong Chen - San Diego CA, US
John Finn - Encinitas CA, US
Thanh To Lam - San Diego CA, US
Suk Joong Lee - San Diego CA, US
Xiaoming Li - San Diego CA, US
Douglas W. Phillipson - Del Mar CA, US
Leslie William Tari - San Diego CA, US
Michael Trzoss - San Diego CA, US
Junhu Zhang - San Diego CA, US
Felice C. Lightstone - Fremont CA, US
Toan B. Nguyen - San Ramon CA, US
Sergio E. Wong - San Jose CA, US
Paul Aristoff - Dexter MI, US
Michael Jung - Los Angeles CA, US
Assignee:

TRIUS THERAPEUTICS, INC. - San Diego CA
International Classification:

C07D 487/04
C07D 471/10
C07D 487/08
C07D 471/08
C07D 487/10
C07D 491/048
C07D 491/056
C07D 487/14
C07D 471/14
C07D 471/04
C07D 498/04
US Classification:

540600, 544250, 544230, 544115, 544105, 544231, 544251
Abstract:

Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors.Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.

Synthetic Catalysts That Separate Co2 From The Atmosphere And Gas Mixtures
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US Patent:

20110151537, Jun 23, 2011
Filed:

Dec 14, 2010
Appl. No.:

12/967262
Inventors:

Felice C. Lightstone - Fremont CA, US
Sergio E. Wong - Campbell CA, US
Edmond Y. Lau - Dublin CA, US
Roger D. Aines - Livermore CA, US
Assignee:

Lawrence Livermore National Security, LLC - Livermore CA
International Classification:

C12N 9/96
US Classification:

435188
Abstract:

The creation of a catalyst that can be used for a wide variety of applications including the steps of developing preliminary information regarding the catalyst, using the preliminary information to produce a template of the catalyst, and using the template of the catalyst to produce the catalyst.

Tricyclic Gyrase Inhibitors
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US Patent:

20170369498, Dec 28, 2017
Filed:

Jul 7, 2017
Appl. No.:

15/643760
Inventors:

- North Wales PA, US
- LIVERMORE CA, US
John Finn - Encinitas CA, US
Thanh T. Lam - San Diego CA, US
Suk J. Lee - San Diego CA, US
Xiaoming Li - San Diego CA, US
Douglas W. Phillipson - Del Mar CA, US
Leslie W. Tari - San Diego CA, US
Michael Trzoss - San Diego CA, US
Junhu Zhang - San Diego CA, US
Felice C. Lightstone - Fremont CA, US
Toan B. Nguyen - Marlborough CA, US
Sergio E. Wong - Tracy CA, US
Paul Aristoff - Dexter MI, US
Michael Jung - Los Angeles CA, US
Assignee:

Merck Sharp & Dohme Corp. - North Wales PA
LAWRENCE LIVERMORE NATIONAL SECURITY, LLC - LIVERMORE CA
International Classification:

C07D 487/04
C07D 487/14
Abstract:

Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors.Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.

Compounds For Reactivation Of Acetylcholinesterase And Related Compositions Methods And Systems
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US Patent:

20170335415, Nov 23, 2017
Filed:

May 15, 2017
Appl. No.:

15/595400
Inventors:

- LIVERMORE CA, US
Nicholas A. BE - OAKLAND CA, US
Brian BENNION - TRACY CA, US
Tim CARPENTER - LIVERMORE CA, US
Heather Ann ENRIGHT - LIVERMORE CA, US
Felice LIGHTSTONE - FREMONT CA, US
Mike MALFATTI - SAN RAMON CA, US
Margaret Windy MCNERNEY - PLEASANTON CA, US
Tuan H. NGUYEN - LIVERMORE CA, US
International Classification:

C07C 251/58
A61K 31/4192
A61K 31/15
C07D 241/04
A61K 31/221
C07D 213/20
Abstract:

Described herein are oxime compounds capable of inactivating a nerve agent, blood brain barrier (BBB)-penetration, and/or reactivation of nerve agent-inhibited acetylcholinesterase (AChE) and related methods, systems and compositions for inactivation of one or more nerve agents, therapeutic and/or prophylactic treatment of an individual, and/or decomposition of nerve agent for decontamination.

Tricyclic Gyrase Inhibitors
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US Patent:

20160222015, Aug 4, 2016
Filed:

Sep 10, 2014
Appl. No.:

15/021314
Inventors:

- Rahway NJ, US
- Livermore CA, US
Zhiyong Chen - San Diego CA, US
Junhu Zhang - San Diego CA, US
Douglas Phillipson - Del Mar CA, US
Suk Joong Lee - San Diego CA, US
Michael Trzoss - San Diego CA, US
Daniel Bensen - Carlsbad CA, US
Xiaoming Li - San Diego CA, US
Min Teng - San Diego CA, US
Voon Ong - San Diego CA, US
Allen John Borchardt - San Diego CA, US
Thanh To Lam - San Diego CA, US
Felice C. Lightstone - Fremont CA, US
Sergio E. Wong - Tracy CA, US
Toan B. Nguyen - Marlborough MA, US
Assignee:

Merck Sharp & Dohme Corp. - Rahway NJ
Lawrence Livermore National Security, LLC - Livermore CA
International Classification:

C07D 487/04
C07F 9/6561
C07D 491/16
Abstract:

Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.

Tricyclic Gyrase Inhibitors
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US Patent:

20150246934, Sep 3, 2015
Filed:

Sep 11, 2013
Appl. No.:

14/427611
Inventors:

- LEXINGTON MA, US
- Livermore CA, US
Zhiyong Chen - San Diego CA, US
John M. Finn - Encinitas CA, US
Thanh To Lam - San Diego CA, US
Suk Joong Lee - San Diego CA, US
Xiaoming Li - San Diego CA, US
Leslie William Tari - San Diego CA, US
Min Teng - San Diego CA, US
Michael Trzoss - San Diego CA, US
Junhu Zhang - San Diego CA, US
Michael E. Jung - Los Angeles CA, US
Felice C. Lightstone - Fremont CA, US
Sergio E. Wong - San Jose CA, US
Toan B. Nguyen - San Ramon CA, US
International Classification:

C07D 519/00
C07D 487/04
Abstract:

Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. In addition, species of tricyclic gyrase inhibitors compounds are also disclosed herein.Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.

Felice Chu Lightstone