Felice C Lightstone

US Patent:

20120238751, Sep 20, 2012

Filed:

Mar 14, 2012

Appl. No.:

13/496188

Inventors:

Daniel Bensen - Carlsbad CA,
Zhiyong Chen - San Diego CA,
John Finn - Encinitas CA,
Thanh To Lam - San Diego CA,
Suk Joong Lee - San Diego CA,
Xiaoming Li - San Diego CA,
Douglas W. Phillipson - Del Mar CA,
Leslie William Tari - San Diego CA,
Michael Trzoss - San Diego CA,
Junhu Zhang - San Diego CA,
Felice C. Lightstone - Fremont CA,
Toan B. Nguyen - San Ramon CA,
Sergio E. Wong - San Jose CA,
Paul Aristoff - Dexter MI,
Michael Jung - Los Angeles CA,

Assignee:

TRIUS THERAPEUTICS, INC. - San Diego CA

International Classification:

C07D 487/04
C07D 471/10
C07D 487/08
C07D 471/08
C07D 487/10
C07D 491/048
C07D 491/056
C07D 487/14
C07D 471/14
C07D 471/04
C07D 498/04

US Classification:

540600, 544250, 544230, 544115, 544105, 544231, 544251

Abstract:

Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors.Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.

US Patent:

20110151537, Jun 23, 2011

Filed:

Dec 14, 2010

Appl. No.:

12/967262

Inventors:

Felice C. Lightstone - Fremont CA,
Sergio E. Wong - Campbell CA,
Edmond Y. Lau - Dublin CA,
Roger D. Aines - Livermore CA,

Assignee:

Lawrence Livermore National Security, LLC - Livermore CA

International Classification:

C12N 9/96

US Classification:

435188

Abstract:

The creation of a catalyst that can be used for a wide variety of applications including the steps of developing preliminary information regarding the catalyst, using the preliminary information to produce a template of the catalyst, and using the template of the catalyst to produce the catalyst.