Feng S Chen

US Patent:

20130103215, Apr 25, 2013

Filed:

Aug 17, 2012

Appl. No.:

13/588634

Inventors:

Jing Dai - White Plains NY, US
Feng Chen - Chappaqua NY, US
Milind R. Naphade - Fishkill NY, US
Sambit Sahu - Hopewell Junction NY, US

Assignee:

INTERNATIONAL BUSINESS MACHINES CORPORATION - Armonk NY

International Classification:

G06Q 50/06

US Classification:

700291

Abstract:

Utility meter readings generated at low sampling rates are disaggregated to identify consumer usage activities. Time intervals between readings can include a plurality of consumer usage activities. By employing a model which recognizes associations among consumer usage activities, effective disaggregation is possible using only aggregated consumption data and interval start times. Consumers and utility managers can design and assess conservation programs based on the disaggregated consumption usage activities.

US Patent:

20130116939, May 9, 2013

Filed:

Nov 3, 2011

Appl. No.:

13/288716

Inventors:

Jing D. Dai - White Plains NY, US
Feng Chen - Falls Church VA, US
Milind R. Naphade - Fishkill NY, US
Sambit Sahu - Hopewell Junction NY, US

Assignee:

INTERNATIONAL BUSINESS MACHINES CORPORATION - Armonk NY

International Classification:

G06F 19/00
G01F 1/74
G06F 17/18
G01R 21/00

US Classification:

702 45, 702188, 702 62, 702181

Abstract:

A computer program product includes a tangible storage medium readable by a processing circuit and on which instructions are stored for execution by the processing circuit for performing a method. The method includes, upon receiving utility consumption data of a group of elements, defining clusters of elements by like geography and like utility consumption, evaluating a significance of each cluster by comparing an average utility consumption within the cluster with utility consumption of elements neighboring the cluster and determining from a result of the evaluating which clusters exhibit significant differences in utility consumption from the neighboring elements and defining those clusters as regional outliers.

US Patent:

20220378924, Dec 1, 2022

Filed:

Jul 18, 2022

Appl. No.:

17/867025

Inventors:

- Monmouth Junction NJ, US
Aranapakam M. VENKATESAN - Rego Park NY, US
Feng CHEN - Princeton NJ, US
Fei WU - Plainsboro NJ, US
Melik Ziya TÜRKER - Princeton NJ, US
Gregory Paul ADAMS - Hatboro PA, US
Francis Y.F. LEE - Yardley PA, US

International Classification:

A61K 47/55
A61K 47/69
A61K 47/60
A61K 47/54
A61P 35/00

Abstract:

The disclosure relates to nanoparticle drug conjugates (NDC) that comprise ultrasmall nanoparticles, folate receptor (FR) targeting ligands, and linker-drug conjugates, and methods of making and using them to treat cancer.

US Patent:

20210121569, Apr 29, 2021

Filed:

Apr 29, 2019

Appl. No.:

17/051928

Inventors:

- New York NY, US
- Ithaca NY, US
Snehal G. Patel - New York NY, US
Feng Chen - New York NY, US
Brian Madajewski - New York NY, US
Daniella Karassawa Zanoni - New York NY, US

International Classification:

A61K 41/00
A61K 47/69
A61K 51/12

Abstract:

Described herein are systems and methods for particle-based photodynamic therapy (PDT) for the treatment of diseases such as cancer of the oral cavity and/or ovarian cancer metastases along the lining of the pelvis. The technology includes an imaging system (e.g., a multichannel imaging camera) configured to perform diagnostic and/or therapeutic treatment on diseased tissue. In certain embodiments, the imaging system comprises one or more excitation sources (e.g., one or more lasers) to assess and/or treat diseased tissue.

US Patent:

20180133342, May 17, 2018

Filed:

Apr 7, 2016

Appl. No.:

15/564315

Inventors:

- New York NY, US
- Ithaca NY, US
- Columbia MO, US
Ulrich Wiesner - Ithaca NY, US
Jason Lewis - New York NY, US
Kai Ma - Ithaca NY, US
Feng Chen - New York NY, US

Assignee:

Memorial Sloan Kettering Cancer Center - New York NY
The Curators of the University of Missouri - Columbia MO
Cornell University - Ithaca NY

International Classification:

A61K 47/69
C07K 16/40
A61K 49/18
A61K 49/00
A61K 45/06
A61K 51/10
A61K 51/12

Abstract:

Disclosed herein are nanoparticle immunoconjugates useful for therapeutics and/or diagnostics. The immunoconjugates have diameter (e.g., average diameter) no greater than 20 nanometers (e.g., as measured by dynamic light scattering (DLS) in aqueous solution, e.g., saline solution). In certain embodiments, the conjugates are silica-based nanoparticles with single chain antibody fragments attached thereto.