Feng Gao

US Patent:

8071107, Dec 6, 2011

Filed:

Sep 17, 2004

Appl. No.:

10/572638

Inventors:

Barton F. Haynes - Durham NC, US
Feng Gao - Durham NC, US
Bette T. Korber - Los Alamos NM, US
Beatrice H. Hahn - Birmingham AL, US
George M. Shaw - Birmingham AL, US
Denise Kothe - Birmingham AL, US
Ying Ying Li - Hoover AL, US
Julie Decker - Alabaster AL, US

Assignee:

Duke University - Durham NC
The Regents of the University of California - Oakland CA
The University of Alabama at Birmingham Research Foundation - Birmingham AL

International Classification:

A61K 39/21
C07H 21/04

US Classification:

4242081, 536 2372

Abstract:

The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralizes a wide spectrum of HIV primary isolates and/or to an immunogen that induces a T cell immune response. The invention also relates to a method of inducing anti-HIV antibodies, and/or to a method of inducing a T cell immune response, using such an immunogen. The invention further relates to nucleic acid sequences encoding the present immunogens.

US Patent:

20090111108, Apr 30, 2009

Filed:

Apr 10, 2007

Appl. No.:

12/226139

Inventors:

Feng Gao - Durham NC, US
Jun Zhu - Durham NC, US

International Classification:

C12Q 1/68

US Classification:

435 6

Abstract:

The present invention relates, in general, to drug resistance, and, in particular, to a method of detecting drug resistance populations, including minor drug resistance viral populations.

US Patent:

20100104596, Apr 29, 2010

Filed:

Mar 27, 2008

Appl. No.:

12/450395

Inventors:

Barton F. Haynes - Durham NC, US
Betle T. Korber - Oakland CA, US
Beatrice H. Hahn - Birmingham AL, US
Tanmoy Bhattacharya - Oakland CA, US
Feng Gao - Durham NC, US
Ron Swanstrom - Chapel Hill NC, US
George Shaw - Birmingham AL, US
Betle T Korber - Oakland CA, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA
DUKE UNIVERSITY - Durham NC
THE UNIVERSITY OF ALABAMA AT BIRMINGHAM - Birmingham AL
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL - Chapel Hill NC

International Classification:

A61K 39/21
A61P 37/04

US Classification:

4242081

Abstract:

The present invention relates, in general, to human immunodeficiency virus (HIV) and, in particular, to a method of inducing an immune response to HIV in a patient and to immunogens suitable for use in such a method. The invention also relates to diagnostic test kits and methods of using same.

US Patent:

20100285106, Nov 11, 2010

Filed:

Nov 19, 2007

Appl. No.:

12/312587

Inventors:

Barton F. Haynes - Durham NC, US
Nancy G. Smith - Durham NC, US
Feng Gao - Durham NC, US

International Classification:

A61K 39/21
A61K 9/127
A61K 39/395
A61P 31/18
A61P 37/04

US Classification:

424450, 4241301, 4241441, 4241601, 4242081

Abstract:

The present invention relates, in general, to human immunodeficiency virus (HIV) and, in particular, to a multicomponent vaccine and method of using same to protect against HTV-I infection.

US Patent:

20110308614, Dec 22, 2011

Filed:

Jun 16, 2010

Appl. No.:

12/816659

Inventors:

Angel R Cartagena - Apex NC, US
Feng Gao - Hockessin DE, US
Haixin Yang - Chapel Hill NC, US
Lei Zhang - Hockessin DE, US

Assignee:

E. I. DU PONT DE NEMOURS AND COMPANY - Wilmington DE

International Classification:

H01L 31/18
H01L 31/0264
C09K 13/00

US Classification:

136261, 252 791, 438 72, 257E31001

Abstract:

This invention provides an etching composition comprising one or more onium salts selected from the group consisting of iodonium salts and sulfonium and an organic medium. Also provided is a method of making a photovoltaic cell that uses the etching composition to etch the anti-reflection coating and a photovoltaic cell made by this method.

US Patent:

20120087938, Apr 12, 2012

Filed:

Aug 23, 2011

Appl. No.:

13/137517

Inventors:

Barton F. Haynes - Durham NC, US
Feng Gao - Durham NC, US
Bette T. Korber - Oakland CA, US
Beatrice H. Hahn - Birmingham AL, US
George M. Shaw - Birmingham AL, US
Denise Kothe - Birmingham AL, US
Ying Ying Li - Birmingham AL, US
Julie Decker - Birmingham AL, US

Assignee:

DUKE UNIVERSITY - Durham NC
THE UNIVERSITY OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION - Birmingham AL
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA

International Classification:

A61K 39/21
A61P 31/18
C12N 15/63
C07K 14/16
C12N 15/49

US Classification:

4241881, 530350, 536 2372, 4353201, 4242081

Abstract:

The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralizes a wide spectrum of HIV primary isolates and/or to an immunogen that induces a T cell immune response. The invention also relates to a method of inducing anti-HIV antibodies, and/or to a method of inducing a T cell immune response, using such an immunogen. The invention further relates to nucleic acid sequences encoding the present immunogens.

US Patent:

20160339051, Nov 24, 2016

Filed:

Sep 26, 2014

Appl. No.:

15/025031

Inventors:

- Durham NC, US
Sallie Permar - Durham NC, US
M. Anthony Moody - Durham NC, US
Feng Gao - Durham NC, US
Georgia Tomaras - Durham NC, US
David C. Montefiori - Durham NC, US

International Classification:

A61K 31/7088
G01N 33/569
C07K 14/005

Abstract:

The invention provides compositions and methods to induce and boost antibody response, including but not limited to IgG responses binding to HIV-1 in a subject in need thereof, wherein the induced/boosted plasma level of the antibody responses, for example V3 and/or CD4 binding site antibody responses, is over a threshold level and is associated with reduced risk of maternal-to-child-transmission (MTCT) of HIV-1.

US Patent:

20140106977, Apr 17, 2014

Filed:

Jun 4, 2013

Appl. No.:

13/909400

Inventors:

Feng GAO - Durham NC, US
Chunfu Yang - Atlanta GA, US
Fangping Cai - Durham NC, US
Guoqing Zhang - Atlanta GA, US

International Classification:

C12Q 1/68

US Classification:

506 9, 506 16

Abstract:

Methods and compositions for simultaneous detection of polymorphisms at multiple loci in a target nucleic acid.