Shengsheng Liu - Richmond VA, US Munmaya K. Mishra - Manakin Sabot VA, US William R. Sweeney - Richmond VA, US Feng Gao - Richmond VA, US
Assignee:
Philip Morris USA Inc. - Richmond VA
International Classification:
A24B 15/00
US Classification:
131352, 131347
Abstract:
A pre-portioned moist product comprising a portion of plant material and a coating is disclosed. Preferably, the plant material comprises tobacco. The coating includes a soluble, non-cross-linkable component and an cross-linkable component which becomes substantially water-insoluble upon crosslinking. The soluble component of the coating dissolves upon placement in the mouth, while the insoluble component disintegrates and/or loses structural integrity once the soluble component has dissolved to release and disperse the plant material in the user's mouth.
Soft, Chewable And Orally Dissolvable And/Or Disintegrable Products
Feng Gao - Richmond VA, US Shalva Gedevanishvili - Richmond VA, US Shengsheng Liu - Richmond VA, US Munmaya K. Mishra - Manakin Sabot VA, US William R. Sweeney - Richmond VA, US Randall Baren - Glen Allen VA, US Qinglin Li - Richmond VA, US Darin Colassaco - Midlothian VA, US Salem Chouchane - Midlothian VA, US
A soft, chewable and orally dissolvable and/or disintegrable product includes a biopolymer-sugar based matrix and botanical powder dispersed throughout the biopolymer-sugar based matrix. The biopolymer-sugar based matrix includes at least one biopolymer, at least one sugar and optional additives. Soft, chewable and orally dissolvable and/or disintegrable product can also include flavor beads.
Moist Smokeless Tobacco Product With Textured Coating
Munmaya K. Mishra - Manakin Sabot VA, US Shengsheng Liu - Richmond VA, US William R. Sweeney - Richmond VA, US Feng Gao - Richmond VA, US Tapashi Sengupta - Barrington IL, US
Assignee:
Philip Morris USA Inc. - Richmond VA
International Classification:
A24B 15/00
US Classification:
131352
Abstract:
A moist smokeless tobacco product for oral use comprises a pre-portioned piece of tobacco material semi-dissolvable, a super-hydrated membrane coating comprising a soluble, non-cross-linked component and an insoluble, cross-linked component, and a texture component. The tobacco material comprises moist smokeless tobacco. The texture component reduces the slipperiness and/or increases the friction of the moist smokeless tobacco product when placed in a user's mouth.
Munmaya K. Mishra - Manakin Sabot VA, US William R. Sweeney - Richmond VA, US Feng Gao - Richmond VA, US
Assignee:
Philip Morris USA Inc. - Richmond VA
International Classification:
A24B 13/00
US Classification:
131352
Abstract:
A pre-portioned moist product comprising a portion of plant material and a coating is disclosed. Preferably, the plant material comprises tobacco. The coating includes a soluble, non-cross-linkable component and an cross-linkable component which becomes substantially water-insoluble upon crosslinking. The soluble component of the coating dissolves upon placement in the mouth, while the insoluble component disintegrates and/or loses structural integrity once the soluble component has dissolved to release and disperse the plant material in the user's mouth.
George R. Pettit - Paradise Valley AZ Feng Gao - Tempe AZ
Assignee:
Arizona Board of Regents, a body corporate, acting on behalf of Arizona State University - Tempe AZ
International Classification:
C07D32300
US Classification:
549264
Abstract:
An intensive long-term investigation of marine organisms as sources of new anticancer drugs has led to the isolation and structural elucidation (primarily by high field NMR and mass spectrometry) of halistatin 2, a new polyether macrolide of the halipyran-type, from the Western Indian Ocean sponge Axinella cf. carteri (Dendy). Halistatin 2 (1. 4. times. 10. sup. -6 % yield) caused the accumulation of cells arrested in mitosis, inhibited tubulin polymerization, and inhibited the binding of radiolabeled vinblastine and GTP to tubulino. Further, Halistatin 2 displayed significant activity against selected human tumor cell lines.
George R. Pettit - Paradise Valley AZ Rui Tan - Tempe AZ Feng Gao - Tempe AZ
Assignee:
Arizona Board of Regents, a body corporate acting on behalf of Arizona State University - Tempe AZ
International Classification:
C07D32300
US Classification:
549267
Abstract:
An intensive long-term investigation of marine organisms as sources of new anticancer drugs has led to the isolation and structural elucidation (primarily by high field NMR and mass spectrometry) of halistatin 1, a new polyether macrolide of the halipyran-type, from the Western Indian Ocean sponge Phakellia carteri. Halistatin 1 (8. 8. times. 10. sup. -7 % yield) caused the accumulation of cells arrested in mitosis, inhibited tubulin polymerization, and inhibited the binding of radiolabeled vinblastine and GTP to tubulin.
George R. Pettit - Paradise Valley AZ Feng Gao - Tempe AZ
Assignee:
Arizona Board of Regents, a body Corporate of The State of Arizona, Acting on behalf of Arizona State University - Tempe AZ
International Classification:
C07D49322 A61K 31365
US Classification:
514450
Abstract:
The marine bryozoan Bugula neritina has been found to contain a novel 22-membered macrocyclic lactone which is an inhibitor of lymphocytic leukemia as measured by the US National Cancer Institute's P 388 and in vitro evaluation system. The novel lactone is herein denominated "neristatin 1" and is elucidated.
An oral pouch product includes an outer wrapper defining a cavity and an inner filling material in the cavity. The outer wrapper includes a hydrophobic material or an elastomeric material. The inner filling material includes a dry mixture and a liquid mixture. The dry mixture includes a cellulosic material. The liquid mixture includes a triglyceride and liquid nicotine dissolved in the triglyceride. The triglyceride is included in the oral pouch product in an amount of 10% to 30% by weight based on the weight of the oral pouch product.
Duke Universitys Feng Gao, who led an analysis published on 29 May in Science about the evolution of SARS-CoV-2, says the new work by Daszak, Shi, and colleagues underscores that researchers have just sampled the tip of the iceberg of the coronaviruses circulating between bats that could jump int
Date: Jun 01, 2020
Category: Health
Source: Google
Evolution of pandemic coronavirus outlines path from animals to humans
"Very much like the original SARS that jumped from bats to civets, or MERS that went from bats to dromedary camels, and then to humans, the progenitor of this pandemic coronavirus underwent evolutionary changes in its genetic material that enabled it to eventually infect humans," said Feng Gao, M.D.