Feng Tian from Arlington, VA, age 43

Novel Activators Of Glucokinase
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US Patent:

20110294758, Dec 1, 2011
Filed:

May 25, 2011
Appl. No.:

13/115647
Inventors:

Feng Tian - Fairfax VA, US
Qun Dang - Westfield NJ, US
G. Sridhar Prasad - San Diego CA, US
Wenyu Li - San Diego CA, US
Brett C. Bookser - San Diego CA, US
Nicholas Brian Raffaele - San Diego CA, US
Mark D. Erion - Del Mar CA, US
Assignee:

Metabasis Therapeutics, Inc. - La Jolla CA
International Classification:

A61K 31/675
C07F 9/38
C07F 9/44
C07F 9/36
A61P 3/00
A61P 3/10
A61P 3/08
A61P 5/50
A61P 1/16
C07F 9/30
C07F 9/6574
US Classification:

514 80, 546 21, 546 23, 548119, 544337, 548113, 544232, 544243, 564 15, 514 89, 514 94, 514 85, 514 93, 514 86, 514119
Abstract:

The present invention provides for novel compounds of Formulas I and II and pharmaceutically acceptable salts and co-crystals thereof which have glucokinsae activator activity. The present invention further provides for pharmaceutical compositions comprising the same as well as methods of treating, preventing, delaying the time to onset or reducing the risk for the development or progression of a disease or condition for which one or more glucokinase activator is indicated, including Type 1 and 2 diabetes, impaired glucose tolerance, insulin resistance and hyperglycemia. The present invention also provides for processes of making the compounds of Formulas I and II, including salts and co-crystals thereof, and pharmaceutical compositions comprising the same.

Apparatus For Processing Biological Samples And Method Thereof
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US Patent:

20130203072, Aug 8, 2013
Filed:

Oct 29, 2010
Appl. No.:

13/879995
Inventors:

Feng Tian - Vienna VA, US
Daniel Liang Zou - Richmond Hill, CA
Lingyun Ji - Wuhan, CN
International Classification:

G01N 1/31
US Classification:

435 71, 422 67, 436501, 4352872
Abstract:

The present invention provides devices, apparatuses and methods for automated processing of biological samples. This invention provides automated devices and automated methods of sequentially treating a biological sample with processing fluids in more than one washing basin. In some embodiments, the invention provides automated devices and automated methods of western blot processing. In some embodiments, the invention provides automated devices and automated methods of Southern blot processing. In some embodiments, the invention provides automated devices and automated methods of northern blot processing. In some embodiments, the invention provides automated devices and automated methods of staining biomolecules on solid supports. In some embodiments, the invention provides automated devices and automated methods of nucleic acid separation and isolation.

Apparatus For Processing Biological Samples
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US Patent:

20150285790, Oct 8, 2015
Filed:

Apr 5, 2015
Appl. No.:

14/679024
Inventors:

Feng Tian - Vienna VA, US
Daniel Liang Zou - Richmond Hill, CA
Lingyun Ji - Wuhan, HB
International Classification:

G01N 33/53
B01L 3/00
B01L 1/00
Abstract:

The present disclosure provides an automated bioprocessing device, which may comprises a processing machine, one or more removable washing cartridges. The removable washing cartridge may comprise a shell, a sample holder, a washing basin, a waste container, a reagent container, a rotation mechanism, and a poking mechanism. The processing machine may comprise a motor, which may provide power to the inserted removable washing cartridge.

Peptide-Based Compounds As Inhibitors Of Neurotransmitter Secretion
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US Patent:

20140286885, Sep 25, 2014
Filed:

Nov 7, 2012
Appl. No.:

14/356387
Inventors:

Feng Tian - Vienna VA, US
Daniel Liang Zou - Richmond Hill, CA
Lingyun Ji - Wuhan, CN
International Classification:

A61K 8/64
A61Q 19/08
US Classification:

424 59, 530329, 514 181, 424 62
Abstract:

The present disclosure is directed to peptide-based compounds, their derivatives, pharmaceutically acceptable salts, solvates and hydrates thereof. The compounds and compositions of the present disclosure may inhibit neurotransmitter release and muscle contraction as a treatment for wrinkles. The compounds of the disclosure may be used for pathological neuronal exocytosis-mediated cosmetic and/or therapeutic purposes.