John C. Byrd - Arlington OH, US Danilo Perrotti - Dublin OH, US Ching-Shih Chen - Upper Arlington OH, US James T. Dalton - Lakeland TN, US Frank Frissora - Columbus OH, US Xiaobin Zhao - Columbus OH, US Qing Liu - Rockville MD, US Natarajan Muthusamy - Galloway OH, US
Assignee:
The Ohio State University Research Foundation - Columbus OH
International Classification:
A61K 31/135
US Classification:
514653, 514 196, 514183, 514424, 435 721
Abstract:
Methods—for treatment and prevention of lymphoid malignancies, including, but not limited to acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), B-cell lymphoma, Acute Myeloid leukemia (AML), and mantle cell lymphoma (MCL). The methods include administration of a therapeutically effective amount of FTY720 (2-Amino-2-[2-(4-octylphenyl)ethyl]propane 1,3-diol hydrochloride) or a derivative, pharmaceutically acceptable salt thereof, or a prodrug thereof to a subject.
Therapeutic Agents For The Treatment Of Lymphoid Malignancies
The Ohio State University Research Foundation - Columbus OH, US Danillo Perrotti - Dublin OH, US Ching-Shih Chen - Upper Arlington OH, US James T. Dalton - Lakeland TN, US Frank Frissora - Columbus OH, US Xiaobin Zhao - Columbus OH, US Qing Liu - Rockville MD, US
Assignee:
The Ohio State University Research Foundation - Columbus OH
International Classification:
A61K 31/137 A61K 45/06
US Classification:
514653
Abstract:
Methods—for treatment and prevention of lymphoid malignancies, including, but not limited to acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), B-cell lymphoma, Acute Myeloid leukemia (AML), and mantle cell lymphoma (MCL). The methods include administration of a therapeutically effective amount of FTY720 (2-Amino-2-[2-(4-octylphenyl)ethyl]propane 1,3-diol hydrochloride) or a derivative, pharmaceutically acceptable salt thereof, or a prodrug thereof to a subject.
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