Lei Yu - Carlsbad CA, US Gang Zhao - Vista CA, US Sang Van - San Diego CA, US Sanjib Das - Oceanside CA, US Zhongling Feng - San Diego CA, US Xiaoli Fu - Vista CA, US Xinghe Wang - San Diego CA, US Yi Jin - Carlsbad CA, US Fu Chen - Carlsbad CA, US
Assignee:
Nitto Denko Corporation - Osaka
International Classification:
A61K 49/10 A61K 49/00 A61K 31/785
US Classification:
424009322, 424009600, 424078270, 525054100
Abstract:
Various biodegradable polyglutamate-amino acids comprising recurring units of the general formulae (I) and (II) are prepared. Such polymers are useful for variety of drug, biomolecule and imaging agent delivery applications.
Lei Yu - Carlsbad CA, US Gang Zhao - Vista CA, US Sang Van - San Diego CA, US Sanjib Kumar Das - Oceanside CA, US Fu Chen - Carlsbad CA, US Yi Jin - Carlsbad CA, US Xiaoli Fu - Vista CA, US
Various biodegradable polyglutamate-amino acids comprising recurring units of the general formulae (I) and (II) are prepared. Such polymers are useful for variety of drug, targeting, stabilizing and/or imaging agent delivery applications.
Lei Yu - Carlsbad CA, US Gang Zhao - Vista CA, US Sang Van - San Diego CA, US Fu Chen - Carlsbad CA, US
Assignee:
Nitto Denko Corporation - Osaka
International Classification:
A61K 9/127 A61K 31/7088
US Classification:
424450, 514 44 R, 514 44 A, 424 783
Abstract:
Compositions that can include a carrier, targeting agent, and therapeutic agent are disclosed herein. The therapeutic agent may have a therapeutic activity such as inhibiting fibrosis within a target organ or tissue or inhibiting the growth of a cancer cell.
Padmanabh Chivukula - San Diego CA, US Jian Liu - San Diego CA, US Akinobu Soma - Carlsbad CA, US Keisaku Okada - San Diego CA, US Sang Van - San Diego CA, US Julia Zhu - Escondido CA, US Nianchun Ma - Oceanside CA, US Chen-Chang Lee - Oceanside CA, US Fu Chen - Carlsbad CA, US Lei Yu - Carlsbad CA, US
Polymers including two or more different recurring units are disclosed herein. Also disclosed herein are methods of using such polymers to deliver nucleic acids to a cell.
Lei Yu - Carlsbad CA, US Gang Zhao - Vista CA, US Sang Van - San Diego CA, US Sanjib Kumar Das - Oceanside CA, US Fu Chen - Carlsbad CA, US Yi Jin - Carlsbad CA, US Xiaoli Fu - Vista CA, US
Assignee:
Nitto Denko Corporation - Osaka
International Classification:
A61K 47/48 A61K 49/12 A61P 35/00 C08G 69/48
US Classification:
424 9365, 525419, 424 7817
Abstract:
Various biodegradable polyglutamate-amino acids comprising recurring units of the general formulae (I) and (II) are prepared. Such polymers are useful for variety of drug, targeting, stabilizing and/or imaging agent delivery applications.
424450, 514 44 R, 514 44 A, 514725, 514559, 514552
Abstract:
Compositions that can include a carrier, targeting agent, and therapeutic agent are disclosed herein. The therapeutic agent may have a therapeutic activity such as inhibiting fibrosis within a target organ or tissue or inhibiting the growth of a cancer cell.
Northrop Grumman Corporation Jul 2000 - Oct 2014
Guidance, Navigation, and Control Engineer
Education:
Uc San Diego 1994 - 1999
Master of Science, Masters, Bachelors, Bachelor of Science, Engineering, Mechanical Engineering
Maranatha Bible College
University of California
Skills:
Uav Systems Engineering Aerospace Simulations Aircraft Flight Test Engineering Simulink Helicopters Sensors Earned Value Management Avionics Engineering Management Systems Design Dod Matlab Aerospace Engineering Security Clearance Space Systems Matrixx Aerodynamics Propulsion Spacecraft Control Systems Design Military Navigation System Design U.s. Department of Defense Aviation Control Theory System Architecture Systems Modeling
Interests:
Children Civil Rights and Social Action Education Poverty Alleviation Disaster and Humanitarian Relief Human Rights
Biotechnology and Colloid/Nanoparticle industry - Greater San Diego Area since Sep 2012
Consultant
Nitto Denko - Greater San Diego Area Jun 2006 - Aug 2012
Senior Scientist, Chief Scientist
Chemical Diversity - Greater San Diego Area 2004 - 2006
Research Scientist
Biota, Inc. - Greater San Diego Area, and Australia 2002 - 2004
PostDoc. and Research Scientist
Education:
McGill University 1996 - 2001
Ph.D., Material Engineering and Phyical/Colloid Chemisrty
Zhongshan University
MS, Analytical Chemisrty
Skills:
Analytical Method Development and Validation For Characterizations Efficient Data Management and Statistical Analysis Instrument Trouble Shooting and Maintenance Polymer Characterization Polymer Science/Chemistry Nanoparticles Formulation Purification Characterization