Gang Chen

US Patent:

8080248, Dec 20, 2011

Filed:

May 14, 2010

Appl. No.:

12/780006

Inventors:

Allen Radin - New York NY, US
Sean Stevens - San Diego CA, US
Tammy T. Huang - Goldens Bridge NY, US
Joel H. Martin - Putnam Valley NY, US
Jeanette L. Fairhurst - White Plains NY, US
Ashique Rafique - Yonkers NY, US
Eric Smith - New York NY, US
Kevin J. Pobursky - Beacon NY, US
Nicholas J. Papadopoulos - LaGrangeville NY, US
James P. Fandl - LaGrangeville NY, US
Gang Chen - Yorktown Heights NY, US
Margaret Karow - Camarillo CA, US

Assignee:

Regeneron Pharmaceuticals, Inc. - Tarrytown NY

International Classification:

A61K 39/395

US Classification:

4241431, 4241301, 4241411, 4241421, 4241441, 514885

Abstract:

The present invention provides methods of preventing or treating rheumatoid arthritis using a fully human antibody or antigen-binding fragment thereof that specifically binds human interleukin-6 receptor (hIL-6R). The methods of the present invention may include administration of a second therapeutic agent, such as one or more of a non-steroidal anti-inflammatory drug (NSAID), a glucocorticoid, a disease-modifying anti-rheumatic drug (DMARD), or a TNF-alpha antagonist, T-cell blocker, anti-CD20 antibody, an IL-1, JAK or IL-17 antagonist, or any combination thereof.

US Patent:

8192741, Jun 5, 2012

Filed:

Nov 1, 2011

Appl. No.:

13/286261

Inventors:

Allen Radin - New York NY, US
Sean Stevens - San Francisco CA, US
Tammy T. Huang - Goldens Bridge NY, US
Joel H. Martin - Putnam Valley NY, US
Jeanette L. Fairhurst - White Plains NY, US
Ashique Rafique - Yonkers NY, US
Eric Smith - New York NY, US
Kevin J. Pobursky - Beacon NY, US
Nicholas J. Papadopoulos - LaGrangeville NY, US
James P. Fandl - LaGrangeville NY, US
Gang Chen - Yorktown Heights NY, US
Margaret Karow - Santa Rosa Valley CA, US

Assignee:

Regeneron Pharmaceuticals, Inc. - Tarrytown NY

International Classification:

A61K 39/395

US Classification:

4241431, 4241301, 4241411, 4241421, 4241441, 514885

Abstract:

The present invention provides methods of preventing or treating rheumatoid arthritis using a fully human antibody or antigen-binding fragment thereof that specifically binds human interleukin-6 receptor (hIL-6R). The methods of the present invention may include administration of a second therapeutic agent, such as one or more of a non-steroidal anti-inflammatory drug (NSAID), a glucocorticoid, a disease-modifying anti-rheumatic drug (DMARD), or a TNF-alpha antagonist, T-cell blocker, anti-CD20 antibody, an IL-1, JAK or IL-17 antagonist, or any combination thereof.

US Patent:

8226241, Jul 24, 2012

Filed:

May 15, 2009

Appl. No.:

12/466790

Inventors:

Gang Chen - Westfield NJ, US
Roland Ryf - Aberdeen NJ, US

Assignee:

Alcatel Lucent - Paris

International Classification:

G03B 21/00
G03B 21/26
H01S 3/10
H01S 3/091
G03H 1/12
G02F 1/135

US Classification:

353 31, 353 94, 372 23, 372 92, 372 71, 372 72, 372 3806, 359 11, 359 27, 349 25, 349 30

Abstract:

An image projector having one or more broadband lasers designed to reduce the appearance of speckle in the projected image via wavelength diversification. In one embodiment, a broadband laser has an active optical element and a nonlinear optical element, both located inside a laser cavity. The broadband laser generates an output spectrum characterized by a spectral spread of about 10 nm and having a plurality of spectral lines corresponding to different spatial modes of the cavity. Different individual spectral lines effectively produce independent speckle configurations, which become intensity-superimposed in the projected image, thereby causing a corresponding speckle-contrast reduction.

US Patent:

8250635, Aug 21, 2012

Filed:

Jul 13, 2008

Appl. No.:

12/172252

Inventors:

Suresh N. Chari - Scarsdale NY, US
Gang Chen - Syosset NY, US
Todd Eric Kaplinger - Raleigh NC, US

Assignee:

International Business Machines Corporation - Armonk NY

International Classification:

G06F 7/04

US Classification:

726 5

Abstract:

A method, system and computer program product for enabling authentication of an OpenID user when a requested identity provider is unavailable. A relying party receives a login request from the OpenID user, where the login request includes a username. The relying party reads a list of trusted identity providers that are associated with the received username and selects one of those identity providers. The relying party generating an OpenID identifier using an identification (e. g. , Uniform Resource Locator) of the selected identity provider and the username. The relying party transmits an authentication request (request to authenticate the OpenID user) to the selected identity provider using the formed OpenID identifier. If the selected identity provider is unavailable, then the relying party selects another identity provider from the list of identity providers that are associated with the received username and repeats the above process.

US Patent:

8390749, Mar 5, 2013

Filed:

Jan 22, 2009

Appl. No.:

12/357835

Inventors:

Gang Chen - Westfield NJ, US
Mihaela Dinu - Freehold NJ, US
Roland Ryf - Aberdeen NJ, US

Assignee:

Alcatel Lucent - Paris

International Classification:

G02F 1/135

US Classification:

349 25, 349 5

Abstract:

A spatial light modulator comprising an array-type liquid crystal panel , a polarization beam splitter , an oblique wave plate and a converging lens. The polarization beam splitter is orientated to direct a source light towards a reflective planar surface of the array-type liquid crystal panel. The oblique wave plate and converging lens are located between the polarization beam splitter and the array-type liquid crystal panel. The converging lens is configured to direct light from the reflective planar surface onto a facing surface of the polarization beam splitter.

US Patent:

8427727, Apr 23, 2013

Filed:

Jan 22, 2009

Appl. No.:

12/357734

Inventors:

Gang Chen - Westfield NJ, US
Roland Ryf - Aberdeen NJ, US
Maria Elina Simon - New Providence NJ, US

Assignee:

Alcatel Lucent - Paris

International Classification:

G02B 26/08

US Classification:

3592241, 3591991, 3591993, 3591994, 3592007, 3592008

Abstract:

An apparatus includes a substrate and a mirror. The mirror is attached to the substrate via a spring. An electro-mechanical driver is operable to cause the mirror to rotationally oscillate about first and second non-collinear axes at different first and second frequencies.

US Patent:

8568721, Oct 29, 2013

Filed:

May 3, 2012

Appl. No.:

13/462938

Inventors:

Allen Radin - New York NY, US
Sean Stevens - San Francisco CA, US
Tammy T. Huang - Goldens Bridge NY, US
Joel H. Martin - Putnam Valley NY, US
Jeanette L. Fairhurst - White Plains NY, US
Ashique Rafique - Yonkers NY, US
Eric Smith - New York NY, US
Kevin J. Pobursky - Beacon NY, US
Nicholas J. Papadopoulos - LaGrangeville NY, US
James P. Fandl - LaGrangeville NY, US
Gang Chen - Yorktown Heights NY, US
Margaret Karow - Santa Rosa Valley CA, US

Assignee:

Regeneron Pharmaceuticals, Inc. - Tarrytown NY

International Classification:

A61K 39/395

US Classification:

4241431, 4241301, 4241411, 4241421, 4241441

Abstract:

The present invention provides methods of preventing or treating rheumatoid arthritis using a fully human antibody or antigen-binding fragment thereof that specifically binds human interleukin-6 receptor (hIL-6R). The methods of the present invention may include administration of a second therapeutic agent, such as one or more of a non-steroidal anti-inflammatory drug (NSAID), a glucocorticoid, a disease-modifying anti-rheumatic drug (DMARD), or a TNF-alpha antagonist, T-cell blocker, anti-CD20 antibody, an IL-1, JAK or IL-17 antagonist, or any combination thereof.

US Patent:

20110234985, Sep 29, 2011

Filed:

Mar 26, 2010

Appl. No.:

12/732504

Inventors:

Roland Ryf - Aberdeen NJ, US
Gang Chen - Bridgewater NJ, US

Assignee:

ALCATEL-LUCENT USA INC. - Murray Hill NJ

International Classification:

G03B 21/14

US Classification:

353 38

Abstract:

An optical device for projecting an image is disclosed. In one embodiment, the optical device includes a configurable optical diffuser adapted to produce a diffuse optical beam having a temporally varying pattern of angular divergence. The optical device further includes a plurality of lenslet pairs to shape the diffuse optical beam and a spatial light modulator to spatially modulate the shaped optical beam to project an image.