Geoffrey K Hom

US Patent:

20030049680, Mar 13, 2003

Filed:

Nov 21, 2001

Appl. No.:

09/990769

Inventors:

D. Gordon - Sommerville MA, US
Geoffrey Hom - Pasadena CA, US
Stephen Mayo - Pasadena CA, US
Niles Pierce - Pasadena CA, US

International Classification:

G01N033/53
G06G007/48
G06G007/58

US Classification:

435/007100, 702/019000, 703/011000

Abstract:

The present invention relates to an apparatus and method for quantitative protein design and optimization. In particular, the invention describes the use of Hybrid Exact Rotamer Optimization algorithms in protein design.

US Patent:

20100099101, Apr 22, 2010

Filed:

Sep 25, 2009

Appl. No.:

12/567669

Inventors:

Timothy W. Behrens - Burlingame CA, US
Robert R. Graham - San Francisco CA, US
Geoffrey Hom - Seattle WA, US
Ward A. Ortmann - Walnut Creek CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

C12Q 1/68

US Classification:

435 6

Abstract:

Methods of identifying, diagnosing, and prognosing lupus, including certain subphenotypes of lupus, are provided, as well as methods of treating lupus, including certain subpopulations of patients. Also provided are methods for identifying effective lupus therapeutic agents and predicting responsiveness to lupus therapeutic agents.

US Patent:

20110046094, Feb 24, 2011

Filed:

May 21, 2008

Appl. No.:

12/600248

Inventors:

Timothy W. Behrens - Burlingame CA, US
Geoffrey Hom - Daly City CA, US
Ward A. Ortmann - Walnut Creek CA, US
Robert R. Graham - San Francisco CA, US

International Classification:

A61K 31/56
C07H 21/04
C12Q 1/68
C40B 40/06
G01N 33/50
C12P 19/34
A61P 37/00
G06Q 90/00

US Classification:

514169, 536 231, 536 2433, 435 6, 506 16, 436 93, 435 912, 705500

Abstract:

A unique set of genetic variations associated with lupus are provided. Also provided are methods for detecting such genetic variations and for assessing risk of developing lupus as well as for diagnosing and treating lupus.