George E Murray

US Patent:

6749811, Jun 15, 2004

Filed:

Oct 16, 2002

Appl. No.:

10/272834

Inventors:

George M. Murray - Columbia MD

Assignee:

The Johns Hopkins University - Baltimore MD

International Classification:

G01N 700

US Classification:

422 91, 422 681, 422 50, 422 52, 422 55, 422 83, 422 88, 422 8205, 422 8207, 422 8208, 436 43, 436164, 436166, 436172, 73 101, 73 102, 73 232, 73 5301

Abstract:

Devices for measuring and detecting a wide variety of analytes, including polyatomic anions, such as organophosphorus pesticides and nerve agents are provided. The devices function by selectively binding an analyte to a luminescent functionality-imprinted copolymer. The copolymers possess a securely bound luminescent lanthanide ion, such as Eu3+, in a coordination complex that has been imprinted to bind the chemical functionality. Also provided are methods for producing the lanthanide-containing molecularly imprinted polymers of the invention.

US Patent:

6780323, Aug 24, 2004

Filed:

Oct 16, 2002

Appl. No.:

10/272733

Inventors:

George M. Murray - Columbia MD

Assignee:

The Johns Hopkins University - Baltimore MD

International Classification:

C02E 142

US Classification:

210638, 21050027, 2105021, 21050034, 21050035, 210651

Abstract:

Molecularly imprinted polymer membranes for selectively collecting phosphate, nitrate and ferric ions are disclosed, prepared by copolymerizing a matrix monomer, cross-linking agent, ion imprinting complex, permeability agent and polymerization initiator, after which the ions of the ion imprinting complex are permeability agent are removed. The permeability agent creates channels in the membrane permitting the ion binding sites in the membrane to communicate with the exterior surface of the membrane.

US Patent:

6852891, Feb 8, 2005

Filed:

Jun 21, 2001

Appl. No.:

10/297626

Inventors:

George M. Murray - Columbia MD, US
Craig A. Kelly - Ellicott City MD, US
O. Manuel Uy - Ellicott City MD, US
Lawrence W. Hunter - Ellicott City MD, US
David S. Lawrence - Ellicott City MD, US

Assignee:

The Johns Hopkins University - Baltimore MD

International Classification:

C07D239/94
C07D401/12
C07D403/12
C07D417/12
C07D409/12

US Classification:

564381, 252193

Abstract:

A method of inhibiting or preventing the use of anhydrous ammonia as a solvent in a dissolving metal reduction process comprises adding to anhydrous ammonia a chemical reagent which is capable of scavenging solvated electrons generated when alkali or alkaline earth metal is dissolved in the anhydrous ammonia, the chemical reagent being added to the anhydrous ammonia such that when alkali metal is dissolved in the anhydrous ammonia containing the chemical reagent and thereafter ephedrine, pseudoephedrine or combination thereof is introduced to the anhydrous ammonia to produce a reaction product, the methamphetamine yield in the reaction product is below 50%, preferably below 10%, and more preferably below 1%. Preferred chemical reagents include Fe(III)citrate, ferrocene, 2-chloro-6-(trichloromethyl)pyridine and 1,1,1,2-tetrafluoroethane.

US Patent:

6872786, Mar 29, 2005

Filed:

Apr 10, 2001

Appl. No.:

10/182518

Inventors:

George M. Murray - Columbia MD, US
Bradley M. Arnold - Columbia MD, US

Assignee:

The Johns Hopkins University - Baltimore MD

International Classification:

C08F026/06

US Classification:

5253267, 525384, 73 3514, 356478

Abstract:

A molecularly imprinted polymeric explosives sensor is provided which possesses selective binding affinity for explosives, such as 2,4,6-trinitrotoluene (TNT) and 1,3,5-trinitrobenzene (TNB). The polymeric sensor incorporates a porphyrin which undergoes a detectable change in absorption and/or emission of electromagnetic radiation when the polymer is exposed to explosives.

US Patent:

7118287, Oct 10, 2006

Filed:

Jul 10, 2001

Appl. No.:

10/030442

Inventors:

Alexander S. Perry - Columbia MD, US
George M. Murray - Columbia MD, US

Assignee:

The Johns Hopkins University - Baltimore MD

International Classification:

G02B 6/38

US Classification:

385 60

Abstract:

A coupler for coupling first and second fiber optic cables terminating in first and second connectors having first and second ferrules, respectively. The coupler includes a holder element and a mating element. The holder element defines a channel for receiving the first ferrule and a socket aligned with the channel for receiving an optical component The holder element further defines a first cable connector adapted for connection to the first connector and a first element connector opposite said first cable connector. The mating element defines a channel for receiving the second ferrule, a second cable connector adapted for connection to the second connector and a second element connector opposite the second cable connector. Accordingly, the holder element and mating element are connectable to house an optical component aligned with the channels and positionable substantially contiguous with the first and second ferrules when attached thereto.

US Patent:

7126148, Oct 24, 2006

Filed:

Jul 17, 2003

Appl. No.:

10/621595

Inventors:

George M. Murray - Columbia MD, US
Harvey W. Ko - Ellicott City MD, US
Glen Southard - Ellicott City MD, US

Assignee:

The Johns Hopkins University - Baltimore MD

International Classification:

G01V 5/10

US Classification:

250900, 2502694, 25039001, 25037005

Abstract:

A system for detecting neutron radiation. A liquid cocktail mixture comprised of a neutron absorber and a scintillator is housed in a Teflon tube having a mirror at one end of the tube and a windowed portal at the other end of the tube. Neutrons that penetrate the tube react with the neutron absorber producing ionization that excites a scintillator to produce photons. A photo-multiplier tube is coupled with the windowed portal for receiving photons and converting the photons to electrical signals. A processing device is coupled to the photo-multiplier output for receiving and analyzing the electrical signals so as to provide a measurement pertaining to the presence and relative strength of neutron radiation. The tube can be adapted to function as a portable survey instrument. Alternatively, the tube can be stretched to cover large apertured areas.

US Patent:

7279096, Oct 9, 2007

Filed:

Aug 24, 2004

Appl. No.:

10/924666

Inventors:

George M. Murray - Columbia MD, US

Assignee:

The Johns Hopkins University - Baltimore MD

International Classification:

B01D 39/00
B01D 39/14
C02E 1/44
B32B 5/02

US Classification:

21050034, 21050027, 2105021, 210638, 521 99, 422 91

Abstract:

Molecularly imprinted polymer membranes for selectively collecting phosphate, nitrate and ferric ions are disclosed, prepared by copolymerizing a matrix monomer, cross-linking agent, ion imprinting complex, permeability agent and polymerization initiator, after which the ions of the ion imprinting complex are permeability agent are removed. The permeability agent creates channels in the membrane permitting the ion binding sites in the membrane to communicate with the exterior surface of the membrane.

US Patent:

7494769, Feb 24, 2009

Filed:

Apr 16, 2003

Appl. No.:

10/503168

Inventors:

George M. Murray - Columbia MD, US
Cheryl S. Schein - Rockville MD, US
David R. Kohler - Ocean Pines MD, US
Jennifer L. Sample - Bethesda MD, US
Jennifer A. Nix - Ellicott City MD, US
Protagoras N. Cutchis - Highland MD, US
Adam K. Arabian - Louisville KY, US
Harvey W. Ko - Ellicott City MD, US
Micah A. Carlson - Baltimore MD, US
Michael P. McLoughlin - Sykesville MD, US

Assignee:

The Johns Hopkins University - Baltimore MD

International Classification:

C12Q 1/70

US Classification:

435 5

Abstract:

A method and apparatus for evaluating a bioaerosol sample is provided which includes detecting frequency and/or time resolution factors that allow discriminate between a plurality of signals emitted by the bioaerosol to selectively detect biological materials contained in the bioaerosol sample from materials of non-biological origin and potentially associated with a pathogenic bioaerosol.