Gil Ma from Englewood, NJ

Us Patents

Adamantyl Diamide Derivatives And Uses Of Same
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US Patent:

7947680, May 24, 2011
Filed:

Jul 17, 2009
Appl. No.:

12/504711
Inventors:

Hermogenes N. Jimenez - Belleville NJ, US
Guiying Li - River Edge NJ, US
Dario Doller - Sparta NJ, US
Michel Grenon - Saddle Brook NJ, US
Andrew D. White - Pinckney MI, US
Gil Ma - Englewood NJ, US
Maojun Guo - Shanghai, CN
Assignee:

H. Lundbeck A/S - Valby-Copenhagen
International Classification:

A61K 31/5377
A61K 31/497
A61K 31/506
A61K 31/444
A61K 31/4155
A61K 31/16
C07D 413/14
C07D 401/02
C07D 403/02
C07D 213/56
C07C 233/00
US Classification:

5142355, 51425505, 514256, 514332, 514406, 514616, 544124, 544333, 544405, 546262, 5483651, 564156
Abstract:

The present invention provides adamantyl-diamide derivatives of formula (I):.

Method For The Asymmetric Synthesis Of Beta-Lactone Compounds
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US Patent:

8124794, Feb 28, 2012
Filed:

Nov 17, 2009
Appl. No.:

12/620412
Inventors:

Jeffrey W. Smith - La Jolla CA, US
Fumiko Axelrod - La Jolla CA, US
Steven J. Kridel - La Jolla CA, US
Daniel Romo - College Station TX, US
Vikram Purohit - College Station TX, US
Gil Ma - College Station TX, US
Assignee:

Sanford-Burnham Medical Research Institute - La Jolla CA
International Classification:

C07D 305/00
US Classification:

549263, 549327, 549328, 549329
Abstract:

The present invention features methods of treating a cancer in a subject by administering an effective amount of a beta-lactone to the subject. The invention also features methods of inhibiting angiogenesis in a subject by administering an effective amount of an inhibitor of fatty acid synthase to the subject. These methods can be used to treat a variety of cancers and other diseases and conditions. The invention also features methods of identifying beta-lactones and other compounds that can be used in the methods of the invention for the treatment of tumors, inhibition of angiogenesis, and the treatment of diseases and conditions that involve pathological angiogenesis. The invention also features methods of synthesizing beta-lactones and features novel beta-lactone compounds.

Adamantyl Diamide Derivatives And Uses Of Same
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US Patent:

8198275, Jun 12, 2012
Filed:

Mar 30, 2011
Appl. No.:

13/075213
Inventors:

Hermogenes N. Jimenez - Belleville NJ, US
Guiying Li - River Edge NJ, US
Dario Doller - Sparta NJ, US
Michel Grenon - Saddle Brook NJ, US
Andrew D. White - Pinckney MI, US
Gil Ma - Englewood NJ, US
Maojun Guo - Pudong, CN
Assignee:

H. Lundbeck A/S - Valby-Copenhagen
International Classification:

A61K 31/5377
A61K 31/497
A61K 31/506
A61K 31/4709
A61K 31/444
A61K 31/4155
A61K 31/16
US Classification:

5142355, 51425505, 514256, 514314, 514332, 514406, 514616
Abstract:

The present invention provides adamantyl-diamide derivatives of formula (I):.

Beta-Lactone Compounds
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US Patent:

8258321, Sep 4, 2012
Filed:

Oct 30, 2008
Appl. No.:

12/262101
Inventors:

Jeffrey W. Smith - La Jolla CA, US
Daniel Romo - College Station TX, US
Gil Ma - College Station TX, US
Manuel Zancanella - College Station TX, US
Assignee:

Burnham Institute for Medical Research - La Jolla CA
The Texas A&M University System - College Station TX
International Classification:

C07D 305/12
US Classification:

549328
Abstract:

The present invention provides compounds having the general structure A, or a pharmaceutically acceptable derivatives thereof:.

Adamantyl Diamide Derivatives And Uses Of Same
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US Patent:

8389519, Mar 5, 2013
Filed:

May 15, 2012
Appl. No.:

13/471611
Inventors:

Hermogenes N. Jimenez - Belleville NJ, US
Guiying Li - River Edge NJ, US
Dario Doller - Sparta NJ, US
Michel Grenon - Saddle Brook NJ, US
Andrew D. White - Pinckney MI, US
Gil Ma - Englewood NJ, US
Maojun Guo - Shanghai, CN
Assignee:

H. Lundbeck A/S - Valby
International Classification:

A61K 31/5377
A61K 31/497
A61K 31/506
A61K 31/4709
A61K 31/444
A61K 31/4155
A61K 31/16
US Classification:

5142355, 51425505, 514256, 514314, 514332, 514406, 514616
Abstract:

The present invention provides adamantyl-diamide derivatives of formula (I):.

Spirolactam Derivatives And Uses Of Same
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US Patent:

8633190, Jan 21, 2014
Filed:

Oct 26, 2010
Appl. No.:

12/912124
Inventors:

Hao Zhou - Paramus NJ, US
Guiying Li - River Edge NJ, US
Dario Doller - Sparta NJ, US
Gil Ma - Englewood NJ, US
Assignee:

H. Lundbeck A/S
International Classification:

A61K 31/535
A61K 31/4965
A61K 31/44
A61K 31/40
C07D 401/02
C07D 295/02
C07D 237/02
C07D 211/92
C07D 277/60
C07D 209/54
US Classification:

5142355, 51425505, 514256, 514278, 514365, 514409, 544 70, 544230, 546 15, 548147, 548408
Abstract:

The present invention provides spirolactam derivatives of formula (I):.

Novel Method For The Asymmetric Synthesis Of Beta-Lactone Compounds
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US Patent:

20060258620, Nov 16, 2006
Filed:

Mar 16, 2006
Appl. No.:

11/378961
Inventors:

Jeffrey Smith - La Jolla CA, US
Fumiko Axelrod - La Jolla CA, US
Steven Kridel - La Jolla CA, US
Daniel Romo - College Station TX, US
Vikram Purohit - College Station TX, US
Gil Ma - College Station TX, US
Assignee:

Burnham Institute for Medical Research - La Jolla CA
International Classification:

A61K 31/695
A61K 31/337
A61K 31/365
US Classification:

514063000, 514449000, 549214000, 549239000
Abstract:

The present invention features methods of treating a cancer in a subject by administering an effective amount of a beta-lactone to the subject. The invention also features methods of inhibiting angiogenesis in a subject by administering an effective amount of an inhibitor of fatty acid synthase to the subject. These methods can be used to treat a variety of cancers and other diseases and conditions. The invention also features methods of identifying beta-lactones and other compounds that can be used in the methods of the invention for the treatment of tumors, inhibition of angiogenesis, and the treatment of diseases and conditions that involve pathological angiogenesis. The invention also features methods of synthesizing beta-lactones and features novel beta-lactone compounds.

Adamantyl Diamide Derivatives And Uses Of Same
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US Patent:

20130184277, Jul 18, 2013
Filed:

Feb 1, 2013
Appl. No.:

13/756710
Inventors:

H. Lundbeck A/S - Valby - Copenhagen, DK
Guiying Li - River Edge NJ, US
Dario Doller - Sparta NJ, US
Michel Grenon - Saddle Brook NJ, US
Andrew D. White - Pinckney MI, US
Gil Ma - Englewood NJ, US
Maojun Guo - Shanghai, CN
Assignee:

H. Lundbeck A/S - Valby - Copenhagen
International Classification:

C07D 401/12
C07D 403/12
C07D 417/12
C07D 409/12
C07D 241/24
C07D 413/14
C07D 413/12
C07D 471/04
C07D 495/04
C07D 213/81
C07D 405/14
US Classification:

5142355, 514332, 514354, 514406, 51425505, 514365, 514341, 514336, 514338, 514314, 514249, 514444, 51425203, 514300, 514340, 514256
Abstract:

The present invention provides adamantyl diamide derivatives of formula (I):wherein Rand Rare as defined herein, or a pharmaceutically acceptable salt thereof; and pharmaceutical compositions and methods using the same.

Senior Scientist Ii

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Location:

Atlanta, GA

Industry:

Food Production

Work:

The Coca-Cola Company - Atlanta, GA since May 2012
Scientist IV, Organic Chemist
Lundbeck - Paramus, NJ Oct 2007 - Aug 2011
Scientist

Education:

Texas A&M University 2005 - 2007
Post-Doc, Organic chemistry University of Pittsburgh 1999 - 2005
Ph.D, Organic Chemistry Seoul National University 1996 - 1998
MS, Organic Chemistry Seoul National University 1990 - 1995
BS, Chemistry

Skills:

Organic Chemistry
Medicinal Chemistry
Synthetic Organic Chemistry
Drug Design
Lc Ms
Chemistry
Organic Synthesis
Hplc
Mass Spectrometry
Purification
Sar
Nmr
Chromatography
Natural Products
Food and Beverage
Polymer Chemistry
Solid State Chemistry
Flavor Chemistry
Sensory Evaluation
Sweetener

Languages:

English
Korean

Gil Ma

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Gil Ma Englewood, NJ

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Work:

Lundbeck Research USA, Inc
Paramus, NJ
Oct 2007 to Aug 2011
Scientist, Medicinal Chemistry Department Department of Chemistry, Texas A&M University
College Station, TX
2005 to 2007
Postdoctoral Research Associate Department of Chemistry, University of Pittsburgh
Pittsburgh, PA
1999 to 2005
Graduate Student Researcher

Education:

University of Pittsburgh
Pittsburgh, PA
Jul 2005
Ph.D. in Chemistry Seoul National University
Seoul, Korea
Jan 1996 to Jan 1998
MS in Organic Chemistry Seoul National University
Seoul, Korea
Jan 1990 to Jan 1995
BS in Chemistry

Skills:

Synthetic Organic Chemistry including route design, multi-step synthesis (over 20 steps), heterocyclic chemistry, organometalic chemistry, polymer-supported reagents, physical organic chemistry, usage of analytical tools (NMR, UV, IR, LCMS, GCMS, HPLC), data analysis (ELN, Scifinder, Spotfire)

Gil Ma

Gil Ma Phones & Addresses

Work

Education

Skills

Us Patents

Adamantyl Diamide Derivatives And Uses Of Same

Method For The Asymmetric Synthesis Of Beta-Lactone Compounds

Adamantyl Diamide Derivatives And Uses Of Same

Beta-Lactone Compounds

Adamantyl Diamide Derivatives And Uses Of Same

Spirolactam Derivatives And Uses Of Same

Novel Method For The Asymmetric Synthesis Of Beta-Lactone Compounds

Adamantyl Diamide Derivatives And Uses Of Same

Resumes

Senior Scientist Ii

Gil Ma

Gil Ma Englewood, NJ

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Gil Ma

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