Gilbert F Rodriguez

US Patent:

6982331, Jan 3, 2006

Filed:

Jun 27, 2003

Appl. No.:

10/608968

Inventors:

Timothy J. Doyle - Elmsford NY, US
Alan H. Benke - Bucks AL, US
Peter K. Wehrenberg - Bucks AL, US
Louie A. Nady - Daphne AL, US
Gilbert Rodriguez - Bucks AL, US

Assignee:

Syngenta Crop Protection, Inc. - Greensboro NC

International Classification:

C07D 409/00
C07D 239/02

US Classification:

544240, 544334

Abstract:

The invention provides a process for synthesizing chlorinated pyrimidines. The process includes reacting imidoyl chloride compounds with phosgene (COCl). The imidoyl chloride compounds can be supplied as starting materials or can be produced by reacting organic amides with phosgene or reacting organic nitrites with hydrogen chloride. Phosgene may be replaced by equivalent reagents. The chlorinated pyrimidines, such as 4,6-dichloropyrimidine, can be used to synthesize other compounds useful in a variety of compositions, such as fungicides, pesticides, and pharmaceuticals.