Guoqing Chen - Palo Alto CA, US Timothy D. Cushing - Pacifica CA, US Paul Faulder - Cheshire, GB Benjamin Fisher - San Mateo CA, US Xiao He - Foster City CA, US Kexue Li - Mountain View CA, US Zhihong Li - Millbrae CA, US Wen Liu - Foster City CA, US Lawrence R. Mcgee - Pacifica CA, US Vatee Pattaropong - Burlingame CA, US Jennifer L. Seganish - Scotch Plains NJ, US Youngshook Shin - Emeryville CA, US Zhulun Wang - Palo Alto CA, US
Selected compounds are effective for prophylaxis and treatment of inflammation and inflammatory disorders, such as NIK-mediated disorders. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, inflammation and the like.