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Haixun Guo

from Louisville, KY

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Also known as:
  • Haixun Gue
  • Guo Haixun
  • N Guo
Phone and address:
305 Hawick Pl, Louisville, KY 40243
Connected to:

Haixun Guo Phones & Addresses

  • 305 Hawick Pl, Louisville, KY 40243
  • Albuquerque, NM

Work

  • Company:
    University of louisville
    Aug 2011
  • Address:
    Louisville, Kentucky Area
  • Position:
    Assistant professor

Education

  • Degree:
    PH.D.
  • School / High School:
    Beijing Normal University
    2002 to 2007
  • Specialities:
    Radiopharmaceutical Science

Skills

Cancer • In Vivo • Cell Culture • Oncology • Imaging • Chemistry • Hplc • Research • Organic Chemistry • Drug Discovery • Molecular Imaging • Medical Imaging • In Vitro • Peptide • Pet/Ct • Spect/Ct

Industries

Research

Resumes

Haixun Guo Photo 1

Assistant Professor

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Location:
Louisville, KY
Industry:
Research
Work:
University of Louisville - Louisville, Kentucky Area since Aug 2011
Assistant Professor
University of New Mexico Jul 2007 - Jul 2011
Postdoc
Education:
Beijing Normal University 2002 - 2007
PH.D., Radiopharmaceutical Science
Skills:
Cancer
In Vivo
Cell Culture
Oncology
Imaging
Chemistry
Hplc
Research
Organic Chemistry
Drug Discovery
Molecular Imaging
Medical Imaging
In Vitro
Peptide
Pet/Ct
Spect/Ct

Us Patents

  • Compounds With Reduced Ring Size For Use In Diagnosing And Treating Melanoma, Including Metastatic Melanoma And Methods Related To Same

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  • US Patent:
    20120225016, Sep 6, 2012
  • Filed:
    Nov 30, 2010
  • Appl. No.:
    13/497738
  • Inventors:
    Yubin Miao - Albuquerque NM, US
    Haixun Guo - Louisville KY, US
  • International Classification:
    A61K 51/08
    A61P 35/00
    A61P 35/04
    C07K 14/68
  • US Classification:
    424 169, 530312
  • Abstract:
    The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.

  • Compounds And Methods For Use In Diagnosing And Treating Melanoma, Including Metastatic Melanoma And Methods Related To Same

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  • US Patent:
    8603435, Dec 10, 2013
  • Filed:
    Jan 12, 2009
  • Appl. No.:
    12/811946
  • Inventors:
    Yubin Miao - Albuquerque NM, US
    Haixun Guo - Albuquerque NM, US
  • Assignee:
    STC.UNM - Albuquerque NM
  • International Classification:
    A61K 51/00
    A61M 36/14
  • US Classification:
    424 169, 424 111, 424 165, 514 11, 530300, 530317, 530327
  • Abstract:
    The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. The present invention represents a step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.

  • Compounds With Reduced Ring Size For Use In Diagnosing And Treating Melanoma, Including Metastatic Melanoma And Methods Related To Same

    view source
  • US Patent:
    20200123216, Apr 23, 2020
  • Filed:
    Sep 27, 2019
  • Appl. No.:
    16/585596
  • Inventors:
    - Albuquerque NM, US
    Haixun Guo - Louisville KY, US
  • International Classification:
    C07K 14/68
    C07K 7/54
    A61K 51/08
    A61K 45/06
  • Abstract:
    The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.

  • Compositions For Use In Diagnosing And Treating Melanoma, Including Metastatic Melanoma And Methods Related To Same

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  • US Patent:
    20190282716, Sep 19, 2019
  • Filed:
    Feb 5, 2019
  • Appl. No.:
    16/267477
  • Inventors:
    - ALBUQUERQUE NM, US
    HAIXUN GUO - LOUISVILLE KY, US
  • International Classification:
    A61K 51/08
    G01N 33/60
    G01N 33/574
    C07K 14/685
    A61K 9/00
    A61K 45/06
  • Abstract:
    The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.

  • Compounds For Use In Diagnosing And Treating Melanoma, Including Metastatic Melanoma And Methods Related To Same

    view source
  • US Patent:
    20160375158, Dec 29, 2016
  • Filed:
    Jun 20, 2016
  • Appl. No.:
    15/186764
  • Inventors:
    - Albuquerque NM, US
    Haixun Guo - Louisville KY, US
  • International Classification:
    A61K 51/08
    A61K 45/06
    A61K 9/00
  • Abstract:
    The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.

  • Compounds With Reduced Ring Size For Use In Diagnosing And Treating Melanoma, Including Metastatic Melanoma And Methods Related To Same

    view source
  • US Patent:
    20150239952, Aug 27, 2015
  • Filed:
    Feb 24, 2015
  • Appl. No.:
    14/629791
  • Inventors:
    - Albuquerque NM, US
    Haixun Guo - Louisville KY, US
  • International Classification:
    C07K 14/68
    A61K 51/08
  • Abstract:
    The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.

  • Compounds With Reduced Ring Size For Use In Diagnosing And Treating Melanoma, Including Metastatic Melanoma And Methods Related To Same

    view source
  • US Patent:
    20150157747, Jun 11, 2015
  • Filed:
    Feb 13, 2015
  • Appl. No.:
    14/622217
  • Inventors:
    - Albuquerque NM, US
    Haixun Guo - Louisville KY, US
  • International Classification:
    A61K 51/08
    A61K 45/06
    C07K 7/54
  • Abstract:
    The present invention is directed to novel non-invasive diagnostic tools/compounds to image cancers, especially, melanoma, including metastatic melanoma in vivo. The present compounds exhibit enhanced uptake in cancerous cells and tissue and decreased renal uptake in kidney, evidencing favorable pharmacokinetics of compounds of the present invention. The compounds according to the present invention represent an advance in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention are also useful for initiating therapy for melanoma as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.

  • Compounds For Use In Diagnosing And Treating Melanoma, Including Metastatic Melanoma And Methods Related To Same

    view source
  • US Patent:
    20140147385, May 29, 2014
  • Filed:
    Oct 30, 2013
  • Appl. No.:
    14/067064
  • Inventors:
    Yubin Miao - Albuquerque NM, US
    Haixun Guo - Albuquerque NM, US
  • International Classification:
    A61K 51/08
  • US Classification:
    424 169, 530321
  • Abstract:
    The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.
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