Hajime Sasaki

US Patent:

8158123, Apr 17, 2012

Filed:

Dec 11, 2003

Appl. No.:

10/734692

Inventors:

Philip Stashenko - Medfield MA, US
Yoshimura Okamatsu - Boston MA, US
Hajime Sasaki - Needham MA, US
Richard Battaglino - Boston MA, US
Ulrike Späte - Boston MA, US

Assignee:

Forsyth Dental Infirmary for Children - Cambridge MA

International Classification:

A61K 39/395

US Classification:

4241301

Abstract:

The present invention features methods of treating a bone resorption disease or a bone generating disease, methods for prognosing and/or diagnosing a bone resorption disease or a bone generating disease, methods for identifying a compound that modulates bone resorption disease development or bone generating disease development, methods for determining the efficacy of a bone resorption disease therapy or a bone generating disease therapy, and oligonucleotide microarrays containing probes for genes involved in osteoclast development.