Hector O Gonzalez

US Patent:

6403835, Jun 11, 2002

Filed:

Nov 2, 2000

Appl. No.:

09/705060

Inventors:

Mark E. Davis - Pasadena CA
Patricia Andy - Mandelieu, FR
Javier Garcia Martinez - Alicante, ES
Gary Lee - Albany CA
Hector Gonzalez - San Francisco CA
Christopher W. Jones - Smyrna GA

Assignee:

California Institute of Technology - Pasadena CA

International Classification:

C07C 4529

US Classification:

568309, 568338, 568 38, 568 44, 544128, 544135, 544146

Abstract:

The invention relates to the shape selective acylation of an organic compound. In particular, the invention describes a process for such acylation wherein the process comprises reducing the number of surface acid sites without dealuminations on at least a portion of the surface of a zeolite and acylating the organic compound in the presence of the zeolite. The organic compounds used in the invention include, for example, olefins, aromatic hydrocarbons, aromatic heterocyclic compounds, and phenolic compounds wherein the organic group may be substituted or unsubstituted. The zeolite may be any natural or synthetic zeolite with a unidimensional or multidimensional network, for example a two-dimensional, or three-dimensional network, or any molecular sieve with structural features similar to these.

US Patent:

6509323, Jan 21, 2003

Filed:

Dec 2, 1998

Appl. No.:

09/203556

Inventors:

Mark E. Davis - Pasadena CA
Hector Gonzalez - San Francisco CA

Assignee:

California Institute of Technology - Pasadena CA

International Classification:

A61K 3170

US Classification:

514 58, 536103, 536105, 536106, 536124

Abstract:

Linear cyclodextrin copolymers and linear oxidized cyclodextrin copolymers containing an unoxidized and/or an oxidized cyclodextrin moiety integrated into the polymer backbone are described. Methods of preparing such copolymers are also described. The linear cyclodextrin copolymer and linear oxidized cyclodextrin copolymer of the invention may be used as a delivery vehicle of various therapeutic agents.

US Patent:

6884789, Apr 26, 2005

Filed:

Mar 15, 2002

Appl. No.:

10/097326

Inventors:

Mark E. Davis - Pasadena CA, US
Hector Gonzalez - San Francisco CA, US

Assignee:

California Institute of Technology - Pasadena CA

International Classification:

A61K031/715
C08B037/16
C08B031/18

US Classification:

514 58, 536103, 536105, 536106, 536124

Abstract:

Linear cyclodextrin copolymers and linear oxidized cyclodextrin copolymers containing an unoxidized and/or an oxidized cyclodextrin moiety integrated into the polymer backbone are described. Methods of preparing such copolymers are also described. The linear cyclodextrin copolymer and linear oxidized cyclodextrin copolymer of the invention may be used as a delivery vehicle of various therapeutic agents.

US Patent:

7091192, Aug 15, 2006

Filed:

Jun 25, 1999

Appl. No.:

09/339818

Inventors:

Mark E. Davis - Pasadena CA, US
Hector Gonzalez - San Francisco CA, US
Suzie Sue Jean Hwang - Torrance CA, US

Assignee:

California Institute of Technology - Pasedena CA

International Classification:

A61K 31/715
C08B 37/16
C08B 31/00
C07H 1/00
C07H 3/00

US Classification:

514 58, 536103, 536105, 536106, 536124

Abstract:

Linear cyclodextrin copolymers and linear oxidized cyclodextrin copolymers containing an unoxidized and/or an oxidized cyclodextrin moiety integrated into the polymer backbone are described. Methods of preparing such copolymers are also described. The linear cyclodextrin copolymer and linear oxidized cyclodextrin copolymer of the invention may be used as a delivery vehicle of various therapeutic agents.

US Patent:

7375096, May 20, 2008

Filed:

Dec 3, 1999

Appl. No.:

09/453707

Inventors:

Mark E. Davis - Pasadena CA, US
Hector Gonzalez - San Francisco CA, US

Assignee:

California Institute of Technology - Pasadena CA

International Classification:

A61K 31/724
A61K 8/11
C12N 15/63

US Classification:

514 58, 424486, 424488, 435455, 527300

Abstract:

A method of preparing a supramolecular complex containing at least one therapeutic agent and a multi-dimensional polymer network is described. A supramolecular complex prepared by a method of the invention is described. A method of treatment by administering a therapeutically effective amount of a supramolecular complex of the invention is also described. Such a supramolecular complex may be used as a delivery vehicle for various therapeutic agents.

US Patent:

7388603, Jun 17, 2008

Filed:

Jun 10, 2003

Appl. No.:

10/457934

Inventors:

Frank N. Cheung - Agoura Hills CA, US
Hector Q. Gonzalez - Torrance CA, US

Assignee:

Raytheon Company - Waltham MA

International Classification:

H04N 5/228
H04N 5/217
H04N 9/64

US Classification:

34820814, 3482084, 3482086, 348241, 348248

Abstract:

An imaging system disables pixel integration for images within frames that are identified as moving while enables pixel integration for images that are not moving. The system may implement a frame-averaging type of integration or recursive types of frame integration, or may refrain from performing frame integration. On a pixel-by-pixel basis, the system may compare a pixel from frame memory with a corresponding pixel of an input frame and may disable pixel integration for the pixel when a difference between the compared pixels exceeds a threshold. One of the integration processes may be performed on the pixels when the difference does not exceed the threshold. When frame integration is disabled or de-selected (e. g. , for pixels having motion), the frame memory may be bypassed and a self-integration may be performed with corresponding pixels from a current frame effectively resulting in no integration. Some embodiments may use multiple thresholds, and may use different integration algorithms depending on conditions within a scene.

US Patent:

8054344, Nov 8, 2011

Filed:

Jun 16, 2006

Appl. No.:

11/454690

Inventors:

Frank N. G. Cheung - Agoura CA, US
Richard Chin - Torrance CA, US
Hector Q. Gonzalez - Westlake Village CA, US

Assignee:

Raytheon Company - Waltham PA

International Classification:

H04N 5/262
H04N 5/225
H04N 7/18

US Classification:

3482402, 348155, 348169

Abstract:

A system and method for zooming an image. In the illustrative embodiment, the system includes a memory for receiving first and second frames of image data; a motion detector for detecting motion in said first or said second frame of image data; and an intelligent zoom system for zooming said first or said second image using a first or a second zoom method based on a detection of motion by said motion detector on a pixel by pixel basis. In the illustrative embodiment, the invention is scene-based, it works on a pixel by pixel basis to determine if a pixel is in motion. It performs motion related zoom for pixels that are affected by motion and conducts cross-field zoom for steady pixels to reduce motion artifacts in zoom mode. Motion may be determined by comparing frame-to-frame pixel value variations to fixed motion threshold(s) or by other algorithms. Independent-field zoom refers to using information from one input field to form a zoomed picture in one associated output field.

US Patent:

20070025952, Feb 1, 2007

Filed:

Feb 21, 2006

Appl. No.:

11/358976

Inventors:

Mark Davis - Pasadena CA, US
Hector Gonzalez - San Francisco CA, US
Suzie Hwang - Torrance CA, US

Assignee:

California Institute of Technology - Pasadena CA

International Classification:

A61K 31/765
A61K 31/724
C08G 63/91

US Classification:

424078300, 514058000, 525054200

Abstract:

Linear cyclodextrin copolymers and linear oxidized cyclodextrin copolymers containing an unoxidized and/or an oxidized cyclodextrin moiety integrated into the polymer backbone are described. Methods of preparing such copolymers are also described. The linear cyclodextrin copolymer and linear oxidized cyclodextrin copolymer of the invention may be used as a delivery vehicle of various therapeutic agents.