Hee O Cho

US Patent:

20210260158, Aug 26, 2021

Filed:

Mar 8, 2021

Appl. No.:

17/194543

Inventors:

- Los Angeles CA, US
Hee Cheol Cho - Los Angeles CA, US

Assignee:

CEDARS-SINAI MEDICAL CENTER - Los Angeles CA

International Classification:

A61K 38/17
C12N 5/077
C07K 14/47
A61K 35/34

Abstract:

Several embodiments disclosed herein relate generally to methods and compositions for the generation of biological pacemakers. In some embodiments, the methods comprise contacting non-pacemaker cells with one or more transcription factors (in vivo or in vitro) and inducing pacemaker functionality in the cells.

US Patent:

20180071364, Mar 15, 2018

Filed:

Aug 16, 2017

Appl. No.:

15/678973

Inventors:

- Los Angeles CA, US
Hee Cheol Cho - Los Angeles CA, US

Assignee:

Cedars-Sinai Medical Center - Los Angeles CA

International Classification:

A61K 38/17
A61K 35/34
C07K 14/47
C12N 5/077

Abstract:

Several embodiments disclosed herein relate generally to methods and compositions for the generation of biological pacemakers. In some embodiments, the methods comprise contacting non-pacemaker cells with one or more transcription factors (in vivo or in vitro) and inducing pacemaker functionality in the cells.

US Patent:

20150359845, Dec 17, 2015

Filed:

Nov 8, 2012

Appl. No.:

14/357195

Inventors:

- Los Angeles CA, US
Hee Cheol Cho - Los Angeles CA, US

Assignee:

CEDARS-SINAI MEDICAL CENTER - Los Angeles CA

International Classification:

A61K 38/17
A61K 35/34

Abstract:

Several embodiments disclosed herein relate generally to methods and compositions for the generation of biological pacemakers. In some embodiments, the methods comprise contacting non-pacemaker cells with one or more transcription factors (in vivo or in vitro) and inducing pacemaker functionality in the cells.