Gretchen Frantz - San Francisco CA, US Kenneth J. Hillan - San Francisco CA, US Heidi Phillips - San Carlos CA, US Paul Polakis - Burlingame CA, US Susan D. Spencer - Tiburon CA, US P. Mickey Williams - Half Moon Bay CA, US Thomas D. Wu - San Francisco CA, US Zemin Zhang - Foster City CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
G01N 33/53
US Classification:
435 71
Abstract:
The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
Compositions And Methods For The Diagnosis And Treatment Of Tumor
Gretchen Frantz - San Francisco CA, US Kenneth J. Hillan - San Francisco CA, US Heidi Phillips - San Carlos CA, US Paul Polakis - Burlingame CA, US Susan D. Spencer - Tiburon CA, US P. Mickey Williams - Half Moon Bay CA, US Thomas D. Wu - San Francisco CA, US Zemin Zhang - Foster City CA, US
Assignee:
Genetech, Inc. - South San Francisco CA
International Classification:
G01N 33/53
US Classification:
435 71
Abstract:
The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
Methods Of Increasing Distribution Of Therapeutic Agents
Krys Bankiewicz - Piedmont CA, US John Hamilton - Washington DC, US Edward Oldfield - Philomont VA, US Heidi Phillips - Palo Alto CA, US
International Classification:
A61K038/19 A61K031/727
US Classification:
424/085100, 514/056000
Abstract:
The present invention provides a method of increasing the volume of distribution of a therapeutic agent in a tissue in a subject during localized delivery comprising administering to the tissue in the subject a therapeutic agent and a facilitating agent, whereby the inclusion of the facilitating agent increases the volume of distribution of the therapeutic agent in the tissue. The invention also provides a method of increasing the pharmacological activity of a therapeutic agent in a tissue in a subject during localized delivery, comprising administering to the tissue in the subject a therapeutic agent and a facilitating agent, whereby the inclusion of the facilitating agent increases the pharmacological activity of the therapeutic agent in the tissue.
Compositions And Methods For The Diagnosis And Treatment Of Tumor
Gretchen Frantz - San Francisco CA, US Kenneth Hillan - San Francisco CA, US Heidi Phillips - San Carlos CA, US Paul Polakis - Burlingame CA, US Susan Spencer - Tiburon CA, US P. Williams - Half Moon Bay CA, US Thomas Wu - San Francisco CA, US Zemin Zhang - Foster City CA, US
Assignee:
GENENTECH, INC.
International Classification:
G01N033/574 C07K016/30
US Classification:
435/007230, 530/388800
Abstract:
The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
Compositions And Methods For The Diagnosis And Treatment Of Tumor
Gretchen Frantz - San Francisco CA, US Kenneth Hillan - San Francisco CA, US Heidi Phillips - Palo Alto CA, US Paul Polakis - Burlingame CA, US Victoria Smith - Burlingame CA, US Susan Spencer - Tiburon CA, US P. Williams - Half Moon Bay CA, US Thomas Wu - San Francisco CA, US Zemin Zhang - Foster City CA, US
Assignee:
GENENTECH, INC.
International Classification:
A61K039/395 C07K016/44
US Classification:
424/141100, 530/388150
Abstract:
The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
Compositions And Methods For The Diagnosis And Treatment Of Tumor
Gretchen Frantz - San Francisco CA, US Kenneth Hillan - San Francisco CA, US Heidi Phillips - San Carlos CA, US Paul Polakis - Burlingame CA, US Susan Spencer - Tiburon CA, US P. Williams - Half Moon Bay CA, US Thomas Wu - San Francisco CA, US Zemin Zhang - Foster City CA, US
The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
Use Of Artemin, A Member Of The Gdnf Ligand Family
David Shelton - Oakland CA, US Heidi Phillips - Palo Alto CA, US
International Classification:
A61K038/17 C12N005/08
US Classification:
514/012000, 435/368000
Abstract:
The present invention concerns the use of artemin for the prevention or treatment of nerve cell injury and changes associated with nerve cell injury. More particularly the present invention provides for a method of protecting neurons in a mammal from injury-induced pathological changes and a method of treating neuronal damage in a mammal by administering artemin or an artemin agonist.
Compositions And Methods For The Diagnosis And Treatment Of Tumor
Gretchen Frantz - San Francisco CA, US Kenneth Hillan - San Francisco CA, US Heidi Phillips - San Carlos CA, US Paul Polakis - Burlingame CA, US Susan Spencer - Tiburon CA, US P. Williams - Half Moon Bay CA, US Thomas Wu - San Francisco CA, US Zemin Zhang - Foster City CA, US
Assignee:
Genentech, Inc.
International Classification:
C07H021/04
US Classification:
536/023200
Abstract:
The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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