Heidi Marie Phillips

US Patent:

7585953, Sep 8, 2009

Filed:

Sep 13, 2005

Appl. No.:

11/226554

Inventors:

Ruihuan Chen - Foster City CA, US
Heidi S. Phillips - Palo Alto CA, US
P. Mickey Williams - Half Moon Bay CA, US
Thomas Wu - San Francisco CA, US
Zemin Zhang - Foster City CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

C07K 16/00
C12P 21/08
A61K 39/395
C12P 21/04
C07H 21/04

US Classification:

5303879, 4241301, 4241331, 4241411, 4241551, 4241791, 4241811, 4241831, 435 696, 5303871, 5303873, 5303881, 5303888, 5303913, 5303917

Abstract:

The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.

US Patent:

7691973, Apr 6, 2010

Filed:

Sep 27, 2006

Appl. No.:

11/529680

Inventors:

Frederic J. de Sauvage - Foster City CA, US
Robert D. Klein - Palo Alto CA, US
Heidi S. Phillips - San Carlos CA, US
Arnon Rosenthal - Burlingame CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

C07K 14/71

US Classification:

530350, 530402

Abstract:

The present invention relates to nucleotide sequences, including expressed sequence tags (ESTs), oligonucleotide probes, polypeptides, vectors and host cells expressing, and immunoadhesions and antibodies to mammalian GFRα3, a novel α-subunit receptor of the GDNF (i. e. GFR) receptor family. It further relates to an assay for measuring activation of an α-subunit receptor by detecting tyrosine kinase receptor activation (i. e. , autophosphorylation) or other activities related to ligand-induced α-subunit receptor homo-dimerization or homo-oligomerization.

US Patent:

7749504, Jul 6, 2010

Filed:

Apr 11, 2007

Appl. No.:

11/733861

Inventors:

Belinda Cairns - Burlingame CA, US
Ruihuan Chen - Palo Alto CA, US
Gretchen Frantz - San Francisco CA, US
Kenneth J. Hillan - San Francisco CA, US
Hartmut Koeppen - Berkeley CA, US
Heidi S. Phillips - Palo Alto CA, US
Paul Polakis - Burlingame CA, US
Susan D. Spencer - Tiburon CA, US
Victoria Smith - Burlingame CA, US
P. Mickey Williams - Half Moon Bay CA, US
Thomas D. Wu - San Francisco CA, US
Zemin Zhang - Foster City CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

A61K 39/395
C12P 21/04
C12P 21/08
C07K 16/00

US Classification:

4241551, 4241331, 4241411, 4241811, 4241831, 435 696, 435 7021, 5303873, 5303879, 5303881, 5303888, 5303917

Abstract:

The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.

US Patent:

7803915, Sep 28, 2010

Filed:

Sep 8, 2004

Appl. No.:

10/936626

Inventors:

Belinda Cairns - Los Altos CA, US
Ruihuan Chen - Palo Alto CA, US
Gretchen Frantz - San Francisco CA, US
Kenneth J. Hillan - San Francisco CA, US
Hartmut Koeppen - Berkeley CA, US
Heidi S. Phillips - Palo Alto CA, US
Paul Polakis - Burlingame CA, US
Susan D. Spencer - Tiburon CA, US
Victoria Smith - Burlingame CA, US
P. Mickey Williams - Half Moon Bay CA, US
Thomas D. Wu - San Francisco CA, US
Zemin Zhang - Foster City CA, US
Chie Sakanaka - San Francisco CA, US
Anan Chuntharapai - Colma CA, US
Chae Janeka Reed - San Francisco CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

C07K 16/00
C12P 21/08
A61K 39/395
C12P 21/04

US Classification:

5303871, 4241301, 4241331, 4241411, 4241551, 4241811, 4241831, 435 696, 435 7021, 5303873, 5303881, 5303888, 5303917

Abstract:

The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.

US Patent:

7939268, May 10, 2011

Filed:

May 15, 2007

Appl. No.:

11/804045

Inventors:

Gretchen Frantz - San Francisco CA, US
Kenneth J. Hillan - San Francisco CA, US
Heidi Phillips - San Carlos CA, US
Paul Polakis - Burlingame CA, US
Susan D. Spencer - Tiburon CA, US
P. Mickey Williams - Half Moon Bay CA, US
Thomas D. Wu - San Francisco CA, US
Zemin Zhang - Foster City CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

G01N 33/53

US Classification:

435 71

Abstract:

The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.

US Patent:

7951546, May 31, 2011

Filed:

May 29, 2008

Appl. No.:

12/156180

Inventors:

Gretchen Frantz - San Francisco CA, US
Kenneth J. Hillan - San Francisco CA, US
Heidi Phillips - San Carlos CA, US
Paul Polakis - Burlingame CA, US
Susan D. Spencer - Tiburon CA, US
P. Mickey Williams - Half Moon Bay CA, US
Thomas D. Wu - San Francisco CA, US
Zemin Zhang - Foster City CA, US

Assignee:

Genetech, Inc. - South San Francisco CA

International Classification:

G01N 33/53

US Classification:

435 71

Abstract:

The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.

US Patent:

8008004, Aug 30, 2011

Filed:

Jan 19, 2007

Appl. No.:

11/625272

Inventors:

Heidi S. Phillips - Palo Alto CA, US

Assignee:

Genentech Inc. - South San Francisco CA

International Classification:

C12Q 1/68
G01N 33/574
G01N 33/55

US Classification:

435 6, 435 71, 435 723

Abstract:

The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumors of glial origin in mammals and to methods of using those compositions of matter for the same.

US Patent:

8278042, Oct 2, 2012

Filed:

Mar 22, 2010

Appl. No.:

12/661704

Inventors:

Belinda Cairns - Burlingame CA, US
Ruihuan Chen - Foster City CA, US
Gretchen Frantz - San Francisco CA, US
Kenneth J. Hillan - San Francisco CA, US
Hartmut Koeppen - Berkeley CA, US
Heidi S. Phillips - Palo Alto CA, US
Paul Polakis - Burlingame CA, US
Susan D. Spencer - Tiburon CA, US
Victoria Smith - Burlingame CA, US
P. Mickey Williams - Half Moon Bay CA, US
Thomas D. Wu - San Francisco CA, US
Zemin Zhang - Foster City CA, US

Assignee:

Genentech, Inc. - South San Francisco CA

International Classification:

C12Q 1/68

US Classification:

435 61

Abstract:

The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.