Helen J Ridgway

US Patent:

20040219682, Nov 4, 2004

Filed:

May 27, 2004

Appl. No.:

10/854708

Inventors:

Helen Ridgway - Beaumont TX, US

International Classification:

G01N033/48

US Classification:

436/069000, 422/061000

Abstract:

A method for determining platelet activation is described. One method includes obtaining a baseline count of platelets in a sample comprising platelets in a liquid medium obtained from a physiological source of the platelets wherein the sample may include an anti-coagulant, adding an activation agonist to the sample and after activation of activatable platelets in the sample, a count of unactivated platelets in the sample is then obtained and the difference between the baseline count of platelets and the count of unactivated platelets is determined. This difference is a measure of the activity of the platelets in the original sample. A kit for determining platelet activation is also described.

US Patent:

20040219681, Nov 4, 2004

Filed:

May 27, 2004

Appl. No.:

10/854707

Inventors:

Helen Ridgway - Beaumont TX, US

International Classification:

G01N033/567

US Classification:

436/069000, 422/061000

Abstract:

Methods for determining platelet activation are described. One method includes obtaining a baseline count of platelets in a sample comprising platelets in a liquid medium obtained from a physiological source of the platelets wherein the sample may include an anti-coagulant, providing a second sample comprising platelets in a liquid medium obtained from a physiological source of the platelets wherein the sample may include an anti-coagulant, adding an activation agonist to the second sample and after activation of activatable platelets in the second sample, a count of unactivated platelets in the second sample is then obtained and the difference between the baseline count of platelets and the count of unactivated platelets is determined. This difference is a measure of the activity of the platelets in the original sample. A kit for determining platelet activation is also described.