Henry Valentin

US Patent:

20090325264, Dec 31, 2009

Filed:

Apr 23, 2009

Appl. No.:

12/428820

Inventors:

MICHAEL J. STOREK - WALTHAM MA, US
HENRY E. VALENTIN - DAVIS CA, US
STEVEN E. SCREEN - ST. LOUIS MO, US
VIRGINIA URSIN - PAWCATUCK CT, US
BYRON FROMAN - DAVIS CA, US
KEVIN JARRELL - LINCOLN MA, US
SARA A. SALVADOR - SUDBURY MA, US
ROBERT MCCARROLL - LEXINGTON MA, US
PRASHANTH VISHWANATH - ARLINGTON MA, US

International Classification:

C12N 9/02
C07H 21/00
C12N 5/04
C12N 5/10

US Classification:

435189, 536 232, 435419, 435416, 435412, 435415, 435414

Abstract:

The present invention provides engineered fatty acid desaturase molecules preferring Gamma Linolenic Acid (GLA) over Linoleic Acid (LA) as a substrate. The invention further discloses compositions, polynucleotide constructs, transformed host cells, transgenic plants and seeds comprising the desaturase molecule, and methods for preparing and using the same. In particular, the disclosed engineered desaturase molecules are capable of altering the omega-3 fatty acid profiles in plants and plant parts.