Henry W Wu

US Patent:

6514207, Feb 4, 2003

Filed:

Apr 16, 2001

Appl. No.:

09/835166

Inventors:

Shahram Ebadollahi - Tarrytown NY
Shih-Fu Chang - New York NY
Henry Wu - New York NY

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

A61B 806

US Classification:

600450

Abstract:

Methods and a system are disclosed for processing an echocardiogram video of a patients heart. The echocardiogram comprises at least a first sequence of consecutive video frames corresponding to a first view of the patients heart concatenated with a second sequence of consecutive video frames corresponding to a second view of the patients heart. The end-diastole phase of the patients heart is monitored in each frame by detecting the electrocardiograph wave, and a key frame is selected upon the occurrence of the R-wave peak in the electrocardiograph wave in each of the first sequence of consecutive video frames and in the second sequence of consecutive video frames. The shape and color content of the echocardiogram image window is monitored in certain video frames, and a transition is detected when there is a change in the first feature between adjacent frames. A summary is generated which comprises by the video frames corresponding to the end-diastole phase.

US Patent:

20110177159, Jul 21, 2011

Filed:

Jan 20, 2011

Appl. No.:

13/010601

Inventors:

HENRY WU - New York NY, US

International Classification:

A61K 9/127
A61K 31/20
A61K 39/395
A61P 9/00
A61P 25/28
A61P 1/04
A61P 17/06
A61P 35/00

US Classification:

424450, 514560, 4241301

Abstract:

A phospholipid microbubble comprising a shell which comprises a plurality of polyunsaturated fatty acid (“PUFA”)-containing phospholipids, and a core of inert gas surrounded by the shell comprising the plurality of PUFA-containing phospholipids. The present invention also provides methods of delivering a prophylactically or therapeutically effective amount of PUFA to an area of disease or injury in a subject. The present invention also provides methods of preventing or treating a disease in a subject using a prophylactically or therapeutically effective amount of the aforementioned phospholipid microbubbles.

US Patent:

20150125519, May 7, 2015

Filed:

Jan 13, 2015

Appl. No.:

14/595695

Inventors:

Henry Wu - New York NY, US

International Classification:

A61K 9/127
A61K 41/00
A61K 31/202

US Classification:

424450, 514560

Abstract:

A phospholipid microbubble comprising a shell which comprises a plurality of polyunsaturated fatty acid (“PUFA”)-containing phospholipids, and a core of paramagnetic gas surrounded by the shell comprising the plurality of PUFA-containing phospholipids. The present invention also provides methods of delivering a prophylactically or therapeutically effective amount of PUFA to an area of disease or injury in a subject. The present invention also provides methods of preventing or treating a disease in a subject using a prophylactically or therapeutically effective amount of the aforementioned phospholipid microbubbles.