Hiten D Madhani

US Patent:

6599705, Jul 29, 2003

Filed:

May 22, 2001

Appl. No.:

09/863040

Inventors:

Steffen Rupp - Stuttgart, DE
Laura Robertson - Cambridge MA
Eric F. Summers - Jamaica Plain MA
Peter Hecht - Newton MA
Radclyffe Roberts - Seattle WA
Hiten Madhani - Brookline MA
Cora Ann Styles - Arlington MA
Hsiu-Jung Lo - Taipei, TW
Amir Sherman - Boston MA
Brian Cali - Somerville MA
Gerald R. Fink - Chestnut Hill MA

Assignee:

The Whitehead Institute for Biomedical Research - Cambridge MA

International Classification:

C12Q 168

US Classification:

435 6, 435441, 435446, 435473

Abstract:

Disclosed herein are methods for regulating fungal gene expression, and reagents for carrying out those methods.

US Patent:

20030078187, Apr 24, 2003

Filed:

Nov 12, 1999

Appl. No.:

09/439969

Inventors:

HITEN D. MADHANI - SAN FRANCISCO CA, US

International Classification:

A01N043/04
A01N061/00
C12Q001/68

US Classification:

514/001000, 514/023000, 435/006000

Abstract:

Assessment of targets of the MAP kinase pathway in the developmental switch between haploid invasive growth and diploid pseudohyphal development in fungi, and identification of genes that show strong regulation by a MAPK pathway-specific transcription factor, Tec1, are described. Also described are methods of identifying an agent which inhibits the filamentation MAPK pathway in a fungus, and methods of inhibiting filamentation of a fungus or invasion of a host by a fungus.

US Patent:

20030235857, Dec 25, 2003

Filed:

Jun 4, 2003

Appl. No.:

10/454210

Inventors:

Steffen Rupp - Stuttgart, DE
Laura Robertson - Cambridge MA, US
Eric Summers - Jamaica Plain MA, US
Peter Hecht - Newton MA, US
Radclyffe Roberts - Seattle WA, US
Hiten Madhani - Brookline MA, US
Cora Styles - Arlington MA, US
Hsiu-Jung Lo - Taipei, TW
Amir Sherman - Boston MA, US
Brian Cali - Somerville MA, US
Gerald Fink - Chestnut Hill MA, US

Assignee:

Whitehead Institute for BioMedical Research, a Delaware corporation

International Classification:

C12Q001/68
C12Q001/18

US Classification:

435/006000, 435/032000

Abstract:

Disclosed herein are methods for regulating fungal gene expression, and reagents for carrying out those methods.

US Patent:

6303302, Oct 16, 2001

Filed:

Nov 10, 1998

Appl. No.:

9/189462

Inventors:

Steffen Rupp - Stuttgart, DE
Laura Robertson - Cambridge MA
Eric F. Summers - Jamaica Plain MA
Peter Hecht - Newton MA
Radclyffe Roberts - Seattle WA
Hiten Madhani - Brookline MA
Cora Ann Styles - Arlington MA
Hsiu-Jung Lo - Taiwan Shiji Town, CN
Amir Sherman - Boston MA
Brian Cali - Somerville MA
Gerald L. Fink - Chestnut Hill MA

Assignee:

The Whitehead Institute for Biomedical Research - Cambridge MA

International Classification:

C12Q 168

US Classification:

435 6

Abstract:

Disclosed herein are methods for regulating fungal gene expression, and reagents for carrying out those methods.