Holger Fuchs

US Patent:

6571118, May 27, 2003

Filed:

May 4, 1999

Appl. No.:

09/304922

Inventors:

Urs Utzinger - Austin TX
Anthony J. Durkin - Watertown MA
Holger Fuchs - Tempe AZ
Ann M. Gillenwater - Pearland TX
Douglas L. Heintzelman - Plainfield IN

Assignee:

Board of Regents, The University of Texas System - Austin TX

International Classification:

A61B 500

US Classification:

600476, 600478, 356318

Abstract:

Methods and apparatus for performing fluorescence and spatially resolved reflectance spectroscopy on a sample. A sample is irradiated with a fluorescence excitation fiber and radiation is collected from the sample with a fluorescence collection fiber and detected to form fluorescence spectra. The sample is also illuminated with a reflectance illumination fiber and reflected light from the sample is collected at a plurality of collection positions and detected to form spatially resolved reflectance spectra. The fibers may form a probe arranged in concentric sections. The spectra are analyzed by pre-processing and reducing the dimensionality of the spectral data.