Hong Lin

US Patent:

20110098597, Apr 28, 2011

Filed:

Oct 13, 2006

Appl. No.:

12/090069

Inventors:

Christine Hsiao-Ming Wu - Santa Clarita CA, US
Guodong Sui - Boca Raton FL, US
Cheng-Chung Lee - Irvine CA, US
Hong Dun Lin - Los Angeles CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

A61B 5/157
C12M 1/26
B01L 99/00

US Classification:

600573, 4353091, 422504

Abstract:

This invention provides microfluidic samplers for withdrawing one or more precise micro- or nano-liter volumes of a sample. The invention provides microfabricated automatic systems comprising integrated poly(dimethyl-siloxane) (PDMS) micro fluidics. The sample can be biological samples, including samples from animals or plants. The samples can be fluid or gas. The samples can comprise a biological fluid, such as blood, tears, cerebral spinal fluid (CSF) and the like, from a test subject such as a human or a mouse. The invention also provides methods for making and using the microfluidic samplers of the invention.