Hong Fan Lin

US Patent:

20030176368, Sep 18, 2003

Filed:

Sep 6, 2002

Appl. No.:

10/236135

Inventors:

Samuel Danishefsky - Englewood NJ, US
Kaustav Biswas - Thouand Oaks NY, US
Mark Chappell - Noblesville IN, US
Hong Lin - New York NY, US
Jon Njardarson - New York NY, US
Chul Lee - Princeton NJ, US
Alexy Rivkin - New York NY, US
Ting-Chao Chou - Paramus NJ, US

International Classification:

C07H017/08
C 07D 4 9/02
A61K031/7048
A61K031/427
A61K031/38
A61K031/365
C07D417/02

US Classification:

514/028000, 514/365000, 514/183000, 514/431000, 514/450000, 536/007400, 548/203000, 540/451000, 549/009000, 549/266000

Abstract:

The present invention provides compounds of formula (I): as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprising compounds of formula (I) and provides methods of treating cancer comprising administering a compound of formula (I).

US Patent:

20110098597, Apr 28, 2011

Filed:

Oct 13, 2006

Appl. No.:

12/090069

Inventors:

Christine Hsiao-Ming Wu - Santa Clarita CA, US
Guodong Sui - Boca Raton FL, US
Cheng-Chung Lee - Irvine CA, US
Hong Dun Lin - Los Angeles CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

A61B 5/157
C12M 1/26
B01L 99/00

US Classification:

600573, 4353091, 422504

Abstract:

This invention provides microfluidic samplers for withdrawing one or more precise micro- or nano-liter volumes of a sample. The invention provides microfabricated automatic systems comprising integrated poly(dimethyl-siloxane) (PDMS) micro fluidics. The sample can be biological samples, including samples from animals or plants. The samples can be fluid or gas. The samples can comprise a biological fluid, such as blood, tears, cerebral spinal fluid (CSF) and the like, from a test subject such as a human or a mouse. The invention also provides methods for making and using the microfluidic samplers of the invention.