Hong Min P Wang

US Patent:

6645747, Nov 11, 2003

Filed:

Sep 6, 2000

Appl. No.:

09/655908

Inventors:

David L. Hallahan - Wilmington DE
Christopher Coldren - Cambridge MA
Dennis Flint - Newark DE
Hong Wang - Kennett Square PA

Assignee:

E. I. du Pont de Nemours and Company - Wilmington DE

International Classification:

C12N 912

US Classification:

435193, 435183, 4352523, 4353201, 435410, 435325, 4352541, 4352542, 536 231, 536 232, 536 234, 536 236

Abstract:

This invention pertains to nucleic acid fragments encoding plant proteins that are homologs to the cis-prenyltransferases UPP synthase from the bacterium or Dedol-PP synthase from yeast. More specifically, this invention pertains to cis-prenyltransferase homologs from wheat, grape, soybean, rice, African daisy, rubber tree latex and pot marigold.

US Patent:

7220405, May 22, 2007

Filed:

Sep 7, 2004

Appl. No.:

10/935642

Inventors:

Xueying Huang - Hockessin DE, US
Hong Wang - Kennett Square PA, US
Ying Wu - Wallingford PA, US

Assignee:

E. I. du Pont de Nemours and Company - Wilmington DE

International Classification:

A61K 8/64
A61Q 5/00
C07K 4/00
C07K 14/00
C12Q 1/70

US Classification:

424 706, 424 701, 424 7014, 435 5, 530324, 530326, 530327, 530329, 530345, 530402, 530408, 530409, 530410

Abstract:

Peptides have been identified that bind with high affinity to hair, skin, and nails. Peptide-based hair conditioners, hair colorants, skin conditioners, skin colorants, and nail colorants are described. The peptide-based hair conditioners and hair colorants consist of a hair-binding peptide coupled to a hair conditioning agent or a coloring agent, respectively. The peptide-based skin conditioners and skin colorants consist of a skin-binding peptide coupled to a skin conditioning agent or a colorant, respectively. The peptide-based nail colorants consist of a nail-binding peptide coupled to a coloring agent. In all these compositions, the peptide may be directly coupled to the active agent or the coupling may be via a spacer. Personal care compositions containing these peptide-based conditioners and colorants are also described.

US Patent:

7309482, Dec 18, 2007

Filed:

Feb 28, 2005

Appl. No.:

11/069858

Inventors:

Janine Buseman-Williams - Greenville DE, US
Xueying Huang - Hockessin DE, US
Hong Wang - Kennett Square PA, US
Gary Ken Whiting - North East MD, US

Assignee:

E.I. du Pont de Nemours and Company - Wilmington DE

International Classification:

A61K 8/02
A61K 8/29
A61K 8/64
A61K 38/02

US Classification:

424 59, 424 709, 424401, 514 6, 977836, 977926

Abstract:

The disclosure provides a sunscreen formulation comprising a peptide-based metal oxide sunscreen agent, such as titanium dioxide nanoparticles, and a fluid vehicle.

US Patent:

7544353, Jun 9, 2009

Filed:

Mar 9, 2007

Appl. No.:

11/716161

Inventors:

Xueying Huang - Hockessin DE, US
Hong Wang - Kennett Square PA, US
Ying Wu - Wallingford PA, US

Assignee:

E.I. du Pont de Nemours and Company - Wilmington DE

International Classification:

A61K 8/64
A61Q 5/00
A61Q 5/12
C07K 4/00
C07K 14/00

US Classification:

424 706, 424 701, 424 7014, 530345

Abstract:

Peptides have been identified that bind with high affinity to hair, skin, and nails. Peptide-based hair conditioners, hair colorants, skin conditioners, skin colorants, and nail colorants are described. The peptide-based hair conditioners and hair colorants consist of a hair-binding peptide coupled to a hair conditioning agent or a coloring agent, respectively. The peptide-based skin conditioners and skin colorants consist of a skin-binding peptide coupled to a skin conditioning agent or a colorant, respectively. The peptide-based nail colorants consist of a nail-binding peptide coupled to a coloring agent. In all these compositions, the peptide may be directly coupled to the active agent or the coupling may be via a spacer. Personal care compositions containing these peptide-based conditioners and colorants are also described.

US Patent:

7632919, Dec 15, 2009

Filed:

Dec 1, 2006

Appl. No.:

11/607673

Inventors:

Scott D. Cunningham - Chadds Ford PA, US
David J. Lowe - Wilmington DE, US
John P. O'Brien - Oxford PA, US
Hong Wang - Kennett Square PA, US
Antoinette E. Wilkins - Newark DE, US

Assignee:

E.I. du Pont de Nemours and Company - Wilmington DE

International Classification:

A61K 38/10
A61K 8/64
C07K 5/04

US Classification:

530327, 514 14

Abstract:

Combinatorially generated peptides are provided that have binding affinity for polystyrene (PS). The peptides may be used to deliver benefit agents to various PS surfaces.

US Patent:

7662587, Feb 16, 2010

Filed:

Mar 5, 2009

Appl. No.:

12/398358

Inventors:

Qiong Cheng - Wilmington DE, US
Kevin Michael Croker - Hockessin DE, US
Kristin Ruebling-Jass - Wilmington DE, US
Hong Wang - Kennett Square PA, US

Assignee:

E. I. du Pont de Nemours and Company - Wilmington DE

International Classification:

C12P 21/06
C12P 21/04
C12P 1/00
C12N 15/74

US Classification:

435 691, 435 697, 435 41, 435183, 435440, 435471

Abstract:

Disrupting the expression of endogenous host cell genes gcvA and spr provides mutant host cells having increased heterologous peptide production relative to control host cells. Recombinant host cells are provided as well as methods of using such host cells for heterologous peptide production.

US Patent:

7662913, Feb 16, 2010

Filed:

Dec 19, 2006

Appl. No.:

11/641273

Inventors:

Linda Jane Decarolis - Wilmington DE, US
Stephen R. Fahnestock - Wilmington DE, US
Hong Wang - Kennett Square PA, US

Assignee:

E. I. du Pont de Nemours and Company - Wilmington DE

International Classification:

C07K 5/00
C07K 7/00
C07K 14/00

US Classification:

530327, 530350

Abstract:

Cystatin-based peptide tags, referred to here as inclusion body tags (IBTs), are disclosed useful for the generation of insoluble fusion peptides. The fusion peptides comprise at least one inclusion body tag operably linked to a peptide of interest. Expression of the fusion peptide in a host cell results in a product that is insoluble and contained within inclusion bodies in the cell and/or cell lysate. The inclusion bodies may then be purified and the protein of interest may be isolated after cleavage from the inclusion body tag.

US Patent:

7666397, Feb 23, 2010

Filed:

Nov 2, 2006

Appl. No.:

11/592108

Inventors:

Xueying Huang - Hockessin DE, US
Hong Wang - Kennett Square PA, US
Ying Wu - Wallingford PA, US

Assignee:

E.I. du Pont de Nemours and Company - Wilmington DE

International Classification:

A61K 8/64
C07K 7/06
C07K 7/08

US Classification:

424 63, 424 64, 424 7803, 530327, 530329, 530345

Abstract:

Peptides have been identified that bind with high affinity to hair, skin, and nails. Peptide-based hair conditioners, hair colorants, skin conditioners, skin colorants, and nail colorants are described. The peptide-based hair conditioners and hair colorants consist of a hair-binding peptide coupled to a hair conditioning agent or a coloring agent, respectively. The peptide-based skin conditioners and skin colorants consist of a skin-binding peptide coupled to a skin conditioning agent or a colorant, respectively. The peptide-based nail colorants consist of a nail-binding peptide coupled to a coloring agent. In all these compositions, the peptide may be directly coupled to the active agent or the coupling may be via a spacer. Personal care compositions containing these peptide-based conditioners and colorants are also described.