Howard E Magadanz

age ~78

from Lafayette, IN

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Also known as:

Howard Eugene Magadanz
Howard Barbara Magadanz
Barbara Magadanz

Phone and address:: 2325 Ellen Dr, Lafayette, IN 47909
(765)4747024

Connected to:

Howard Magadanz Phones & Addresses

2325 Ellen Dr, Lafayette, IN 47909 • (765)4747024
2325 Ellen Dr, Lafayette, IN 47909 • (317)4747024

Work

Position:

Professional/Technical

Education

Degree:

Graduate or professional degree

Us Patents

Reductive Alkylation Of Glycopeptide Antibiotics
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US Patent:

59524669, Sep 14, 1999
Filed:

Nov 12, 1997
Appl. No.:

8/968968
Inventors:

Richard Alan Berglund - Lafayette IN
Nancy Anne Lockwood - Mountlake Terrace WA
Howard Eugene Magadanz - Lafayette IN
Hua Zheng - Lafayette IN
Assignee:

Eli Lilly and Company - Indianpolis ID
International Classification:

A61K 3800
C07K 512
US Classification:

530345
Abstract:

This invention is concerned with improved processes for reductive alkylation of glycopeptide antibiotics. The improvement residing in providing a source of copper which results in the initial production of a copper complex of the glycopeptide antibiotic. Reductive alkylation of this complex favors regioselective alkylation and increased yields. Copper complexes of the glycopeptide antibiotic starting materials and of the alkylated products are also part of the invention.

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