Hui Li

US Patent:

7115658, Oct 3, 2006

Filed:

May 9, 2003

Appl. No.:

10/434702

Inventors:

Allen J. Borchardt - San Diego CA, US
Peter Scott Dragovich - San Diego CA, US
Javier Gonzalez - Oceanside CA, US
Tanya Michelle Jewell - Encinitas CA, US
Hui Li - Carlsbad CA, US
Maria Angelica Linton - San Diego CA, US
John Howard Tatlock - San Diego CA, US
Ru Zhou - Carlsbad CA, US
Thomas Jay Prins - Cardiff CA, US
Melwyn A. Abreo - Jamul CA, US

Assignee:

Agouron Pharmaceuticals, Inc. - San Diego CA

International Classification:

A61K 31/351

US Classification:

514460, 514459, 514336, 514365, 514452, 514364, 514378, 514405, 514326, 5142315, 514422, 51425931, 514384, 514397, 5142621, 514456, 5142581, 514382, 51425505, 514369, 514274, 514340, 514363, 514375, 5142541

Abstract:

Compounds of formula I are hepatitis C virus (HCV) RNA-dependent RNA polymerase (RdRp) inhibitors, and are useful in therapeutic and prophylactic treatment of persons infected with hepatitis C virus.

US Patent:

7148226, Dec 12, 2006

Filed:

Nov 19, 2003

Appl. No.:

10/718337

Inventors:

Allen Borchardt - San Diego CA, US
Javier Gonzalez - Oceanside CA, US
Hui Li - Carlsbad CA, US
Maria Angelica Linton - Linton CA, US
John Howard Tatlock - San Diego CA, US

Assignee:

Agouron Pharmaceuticals, Inc. - San Diego CA

International Classification:

A61K 31/519

US Classification:

5142591, 514397, 514378, 514394, 5142631, 51426323, 514406, 514414, 514383, 544264, 544278, 5482632, 5482642, 5483047, 5483657

Abstract:

The invention relates to compounds of the formula 1.

US Patent:

7473790, Jan 6, 2009

Filed:

May 8, 2006

Appl. No.:

11/382154

Inventors:

Allen Borchardt - San Diego CA, US
Javier Gonzalez - Oceanside CA, US
Hui Li - Carlsbad CA, US
Maria Angelica Linton - San Diego CA, US
John Howard Tatlock - San Diego CA, US

Assignee:

Pfizer Inc. - New York NY

International Classification:

C07D 309/30
C07D 305/00
C07D 309/00

US Classification:

549291, 549263, 549273

Abstract:

The invention relates to compounds of the formula 1.

US Patent:

8114871, Feb 14, 2012

Filed:

Apr 10, 2008

Appl. No.:

12/532051

Inventors:

Iriny Botrous - San Diego CA, US
Yufeng Hong - San Diego CA, US
Hui Li - Carlsbad CA, US
Kevin Kun-Chin Liu - San Marcos CA, US
Seiji Nukui - San Diego CA, US
Min Teng - San Diego CA, US
Eileen Valenzuela Tompkins - Escondido CA, US
Chunfeng Yin - San Diego CA, US

Assignee:

Pfizer Inc. - New York NY
Pfizer Products Inc. - Groton CT

International Classification:

A61K 31/535
A61K 31/495
A61K 31/497
A61K 31/4965
C07D 413/14
C07D 237/00
C07D 239/00
C07D 403/14
C07D 241/36
C07D 401/14

US Classification:

5142342, 514249, 51425309, 51425406, 514250, 51425506, 544121, 544230, 544231, 544282, 544295, 544344, 544349, 544363, 544371

Abstract:

The present invention relates to compounds and pharmaceutically acceptable salts of Formula (I): wherein X, R, R, R, R, R, R, R, and Rare as defined above. The invention further relates to pharmaceutical compositions comprising the compounds and pharmaceutically acceptable salts and to methods of treating diabetes mellitus and its complications (including in particular diabetic retinopathy, nephropathy or neuropathy), cancer, ischemia, inflammation, central nervous system disorders, cardiovascular disease, Alzheimer's disease and dermatological disease pression, viral diseases, inflammatory disorders, or diseases in which the liver is a target organ.

US Patent:

8183255, May 22, 2012

Filed:

Feb 4, 2008

Appl. No.:

12/523965

Inventors:

Hui Li - Carlsbad CA, US
Seiji Nukui - San Diego CA, US
Stephanie Anne Scales - San Diego CA, US
Min Teng - San Diego CA, US
Chunfeng Yin - San Diego CA, US

Assignee:

Pfizer, Inc. - New York NY

International Classification:

A61K 31/505

US Classification:

514275, 544324, 544386, 546245, 5483605, 549356

Abstract:

The present invention relates to compounds and pharmaceutically acceptable salts of Formulas A and B: (A) and (B) wherein A, B, R, R, R, R, R, R, R, R, Rand Rare as defined above. The invention further relates to pharmaceutical compositions comprising the compounds and pharmaceutically acceptable salts and to methods of treating diabetes mellitus and its complications, cancer, ischemia, inflammation, central nervous system disorders, cardiovascular disease, Alzheimer's disease and dermatological disease pression, virus diseases, inflammatory disorders, or diseases in which the liver is a target organ.

US Patent:

8200426, Jun 12, 2012

Filed:

Aug 22, 2001

Appl. No.:

09/935463

Inventors:

Qing Kent Pu - San Diego CA, US
Hui Henry Li - San Diego CA, US

Assignee:

Infogation Corporation - San Diego CA

International Classification:

G01C 21/26

US Classification:

701412, 701408

Abstract:

A client navigation system establishes a wireless connection to a navigation server on a computer network. The client requests a route by uploading start and stop specifications. The server calculates an optimal route based on real-time data available on the network. A generic natural language description is used to specify the optimal route downloaded to the client. The natural language description is independent from the local mapping database software on the client and includes a plain text description for each link using pre-defined generic terms. The client interprets the route, interfaces with the local mapping database and reconstructs the optimal route using a mapping reconstruction algorithm. The route is displayed on the client navigation system using whatever mapping database is present. An enhanced user-interface data-entry feature is provided that anticipates data being entered by users to minimize the data-entry process.

US Patent:

8518952, Aug 27, 2013

Filed:

Aug 4, 2009

Appl. No.:

13/057558

Inventors:

John Frederick Braganza - San Diego CA, US
Michael Raymond Collins - San Diego CA, US
John Charles Kath - La Mesa CA, US
Sacha Ninkovic - La Jolla CA, US
Hui Li - Carlsbad CA, US
Daniel Tyler Richter - San Diego CA, US

Assignee:

Pfizer Inc. - New York NY

International Classification:

A61K 31/497

US Classification:

51425505, 544405

Abstract:

The present invention is directed to compounds of formula (I),.

US Patent:

8600664, Dec 3, 2013

Filed:

Jun 10, 2012

Appl. No.:

13/492901

Inventors:

Qing Kent Pu - San Diego CA, US
Hui Henry Li - San Diego CA, US

Assignee:

InfoGation Corporation - San Diego CA

International Classification:

G01C 21/26

US Classification:

701420, 701533

Abstract:

A client navigation system establishes a wireless connection to a navigation server on a computer network. The client requests a route by uploading start and stop specifications. The server calculates an optimal route based on real-time data available on the network. A generic natural language description is used to specify the optimal route downloaded to the client. The natural language description is independent from the local mapping database software on the client and includes a plain text description for each link using pre-defined generic terms. The client interprets the route, interfaces with the local mapping database and reconstructs the optimal route using a mapping reconstruction algorithm. The route is displayed on the client navigation system using whatever mapping database is present.