Hui Qun Li

US Patent:

7919628, Apr 5, 2011

Filed:

Jun 29, 2007

Appl. No.:

11/771958

Inventors:

Stephanie Hachtel - Frankfurt, DE
Juergen Dedio - Mainz-Kastel, DE
Holger Heitsch - Mainz-Kastel, DE
Werngard Czechtizky - Frankfurt, DE
Sven Grueneberg - Kelkheim, DE
Stephen J. Shimshock - Hillsborough NJ, US
Carolina L. Lanter - Audubon PA, US
Hui Li - Neshanic Station NJ, US
Rosy Sher - Bridgewater NJ, US
Aleksandra Weichsel - Tucson AZ, US

Assignee:

Sanofi-Aventis Deutschland GmbH - Frankfurt am Main

International Classification:

C07D 277/64
A61K 31/426

US Classification:

548179, 514367

Abstract:

The invention relates to compounds of the formula I:.

US Patent:

8283479, Oct 9, 2012

Filed:

Apr 4, 2011

Appl. No.:

13/079522

Inventors:

Stephanie Hachtel - Frankfurt, DE
Juergen Dedio - Mainz-Kastel, DE
Holger Heitsch - Mainz-Kastel, DE
Werngard Czechtizky - Frankfurt, DE
Sven Grueneberg - Kelkheim, DE
Stephen J. Shimshock - Hillsborough NJ, US
Carolina L. Lanter - Audubon PA, US
Hui Li - Neshanic Station NJ, US
Rosy Sher - Bridgewater NJ, US
Aleksandra Weichsel - Tucson AZ, US

Assignee:

Sanofi-Aventis Deutschland GmbH - Frankfurt am Main

International Classification:

C07D 333/66
C07D 409/12
A61K 31/44

US Classification:

549 55, 5462811, 514338

Abstract:

The invention relates to compounds of the formula I:.

US Patent:

20100332499, Dec 30, 2010

Filed:

Jun 26, 2009

Appl. No.:

12/493097

Inventors:

Yufei Pan - North Brunswick NJ, US
Hui Li - Edison NJ, US
Justin Sarma - New York NY, US
David Soukal - Bothell WA, US
Alessio Signorini - Boulder CO, US
Apostolos Gerasoulis - Edison NJ, US
Tomasz Imielinski - Princeton NJ, US

Assignee:

IAC SEARCH & MEDIA, INC. - New York NY

International Classification:

G06F 17/30

US Classification:

707759, 707769

Abstract:

In a method for a direct answer for search, a search query is received over a network, one or more answer candidate snippets for the search query are received, with an answer candidate snippet having at least a portion of content available over the network for an answer candidate, one or more answer entities are determined within a selected answer candidate snippet, a frequency of the one or more answer entities found within the one or more answer candidate snippets for the search query is determined, a confidence score is adjusted for the selected answer candidate in accordance with the frequency of the one or more answer entities found within the one or more answer candidate snippets, and at least one answer candidate snippet is sent for a response to the search query.

US Patent:

20210017171, Jan 21, 2021

Filed:

Jun 26, 2020

Appl. No.:

16/914209

Inventors:

- South San Francisco CA, US
Chengguo DONG - Staten Island NY, US
Timothy HOM - Sunnyvale CA, US
Lan JIANG - Foster City CA, US
Katerina LEFTHERIS - San Mateo CA, US
Hui LI - Santa Clara CA, US
Manuel MUNOZ - Vallejo CA, US
Maureen REILLY - Burlingame CA, US
Yajun ZHENG - Foster City CA, US

International Classification:

C07D 471/04
C07D 519/00

Abstract:

The invention relates to compounds of formula (A) and formula (I):or a salt thereof, wherein R, R, R, R, R, R, R, R, R, q and p are as described herein. Compounds of formula (A), formula (I), and pharmaceutical compositions thereof are αvβ6 integrin inhibitors that are useful for treating fibrosis such as idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).

US Patent:

20200352942, Nov 12, 2020

Filed:

Apr 8, 2020

Appl. No.:

16/843824

Inventors:

- South San Francisco CA, US
Chengguo DONG - Staten Island NY, US
Timothy HOM - Sunnyvale CA, US
Lan JIANG - Foster City CA, US
Katerina LEFTHERIS - San Mateo CA, US
Hui LI - Santa Clara CA, US
Manuel MUNOZ - Vallejo CA, US
Maureen REILLY - Burlingame CA, US
Yajun ZHENG - Foster City CA, US
Martin DECARIS - Oakland CA, US
Scott TURNER - Oakland CA, US

International Classification:

A61K 31/5025
A61K 31/502
A61K 31/4375
A61K 9/00
A61P 11/00

Abstract:

The invention relates to dosage forms for daily administration of compounds of formula (A) and formula (I):or a salt thereof, wherein R, R, R, R, R, R, R, R, R, q and p are as described herein. Compounds of formula (A), formula (I), and pharmaceutical compositions thereof are αvβ6 integrin inhibitors that are useful for treating fibrosis such as idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).

US Patent:

20200114091, Apr 16, 2020

Filed:

Dec 12, 2019

Appl. No.:

16/712364

Inventors:

- Madison NJ, US
Hui Li - Cranbury NJ, US
Ming F. Pomerleau - Califon NJ, US
Darin Messina - Branchburg NJ, US

International Classification:

A61M 5/32
A61K 35/12
A61K 47/36

Abstract:

Tissue product compositions and methods for treating a patient are provided. The tissue product composition may include a flowable carrier including a hyaluronic acid based material and acellular tissue matrix particles mixed within the carrier. Methods of producing the tissue product composition and an injection device filled with the tissue product composition are also provided. Methods of treating a hand of a patient are also provided.

US Patent:

20190276449, Sep 12, 2019

Filed:

Mar 7, 2019

Appl. No.:

16/296194

Inventors:

- South San Francisco CA, US
Chengguo DONG - Staten Island NY, US
Timothy HOM - Sunnyvale CA, US
Lan JIANG - Foster City CA, US
Katerina LEFTHERIS - San Mateo CA, US
Hui LI - Santa Clara CA, US
Manuel MUNOZ - Vallejo CA, US
Maureen REILLY - Burlingame CA, US
Yajun ZHENG - Foster City CA, US

International Classification:

C07D 471/04
C07D 519/00

Abstract:

The invention relates to compounds of formula (A) and formula (I):or a salt thereof, wherein R, R, R, R, R, R, R, R, R, q and p are as described herein. Compounds of formula (A), formula (I), and pharmaceutical compositions thereof are αvβ6 integrin inhibitors that are useful for treating fibrosis such as idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).

US Patent:

20190099520, Apr 4, 2019

Filed:

Oct 3, 2018

Appl. No.:

16/150387

Inventors:

- Madison NJ, US
Hui Xu - Plainsboro NJ, US
Hui Li - Cranbury NJ, US
Nathaniel Bachrach - Clifton NJ, US

International Classification:

A61L 27/36
A61K 35/32
A61L 27/26

Abstract:

Devices, methods of producing devices, and methods of treating an anatomic defect are provided. The devices and methods can include a flexible sheet of acellular tissue matrix and one or more elongated synthetic elements. The one or more synthetic elements may extend through the flexible sheet such that the one or more synthetic elements extend substantially parallel to a first top surface and a second bottom surface within one or more portions of the flexible sheet, and may be exposed on one or more portions of the first top surface of the device.