Hui Lu

US Patent:

7838571, Nov 23, 2010

Filed:

Oct 22, 2004

Appl. No.:

10/576635

Inventors:

Christopher N. Bowman - Boulder CO, US
Hui Lu - Dover DE, US
Jeffrey W. Stansbury - Centennial CO, US

Assignee:

The Regents of the University of Colorado - Denver CO

International Classification:

A61K 6/087
A61K 6/08
C08G 75/00

US Classification:

522 44, 522 48, 522167, 522180, 523115, 523116

Abstract:

Photopolymerizable polymer composites based on dimethacrylate systems have been increasingly utilized as dental restorative materials. One of the biggest drawbacks of current dental resin systems is the volume shrinkage and shrinkage induced stresses that arise during the polymerization. Other major problems include incomplete double bond conversion and insufficient wear resistance. This invention involves the development of an entirely novel approach to the photopolymerization process that utilizes thiol-ene systems as low shrinkage and ultra-low shrinkage stress dental restorative materials. Compared with the traditional dimethacrylate dental resins, these novel photopolymerizations have demonstrated a dramatically decreased volume shrinkage, extremely rapid polymerization, abilities to photopolymerize ultrathick materials and achieve much higher conversion, lack of oxygen inhibition and ultra-low shrinkage stress due to low volume shrinkage and drastically delayed gel point conversion. These polymers have thus shown outstanding suitability as dental restorative materials.

US Patent:

20070185230, Aug 9, 2007

Filed:

Mar 8, 2005

Appl. No.:

10/598641

Inventors:

Christopher Bowman - Boulder CO, US
Carioscia Jacquelyn - Broomfield CO, US
Hui Lu - Boulder CO, US
Jeffrey Stansbury - Aurora CO, US

Assignee:

The Regents of the University of Colorado CU Technology Transfer Office - Boulder CO

International Classification:

A61K 6/083

US Classification:

523115000

Abstract:

The present invention provides a dental composition comprising a curable blend of one or more polythiol compounds and one or more polyvinyl compounds; where one or both compounds are oligomers. In one aspect, the polythiol compounds are polythiol oligomers formed by prepolymerization of polyvinyl monomers in the presence of an excess of polythiol monomers. In another aspect, the polyvinyl compounds are polyvinyl oligomers formed by prepolymerization of polythiol monomers in the presence of an excess of polyvinyl monomers. The dental composition may further comprise one or more fillers or photoinitiators known in the art. The invention also comprises methods of making a dental prosthesis comprising the composition described above. Use of the thiol-ene oligomeric system results in cured (polymerized) dental compositions having improved physical properties, including low-shrinkage properties and reduced shrinkage induced-stress, enhanced double bond conversion percentage, and reduced odor.

US Patent:

20080274335, Nov 6, 2008

Filed:

Dec 16, 2005

Appl. No.:

11/722074

Inventors:

Christopher N. Bowman - Boulder CO, US
Sirish Reddy - Hills Boro OR, US
Neil Cramer - Boulder CO, US
Robert P. Sebra - San Francisco CA, US
Hui Lu - Dover DE, US

Assignee:

REGENTS OF THE UNIVERSITY OF COLORADO - Boulder CO

International Classification:

B32B 3/30
C08J 3/28
C08G 75/04

US Classification:

428167, 528376, 528 32, 528364, 528321, 528 75, 522134

Abstract:

The present invention provides a method for modifying a surface of a polymer derived from a mixture comprising a thiol monomer and an olefinic monomer. The method comprises exposing at least a portion of the polymer surface to electromagnetic radiation of sufficient energy to modify the polymer surface. The present invention also provides a polymer derived from polymerizing a mixture of monomers comprising a thiol monomer, an olefinic monomer, and an iniferter.

US Patent:

20110275035, Nov 10, 2011

Filed:

May 2, 2011

Appl. No.:

13/098562

Inventors:

Hui Lu - Magnolia DE, US

Assignee:

DENTSPLY International Inc. - York PA

International Classification:

A61C 5/04
A61C 17/00
A61K 6/083

US Classification:

433216, 523116

Abstract:

A self-etching and self-adhesive dental restorative composition is described herein. The composition includes a polymerizable compound having at least one phosphorus containing acidic group, a polymerizable compound having at least one carboxylic acid group, and a copolymerizable multi-functional (meth)acrylate monomers. Compositions described herein demonstrate adhesion to dentin and enamel and are useful as a cavity filler, dental pit and fissure sealants, and restoratives.

US Patent:

20130323685, Dec 5, 2013

Filed:

Jun 4, 2013

Appl. No.:

13/909549

Inventors:

Hui LU - Magnolia DE, US

International Classification:

A61K 6/083
A61C 13/15

US Classification:

4332281, 522 81, 522 47, 522 68, 522 64, 522 37

Abstract:

A dental restorative composite and a method of curing the composite are disclosed in which the composite includes a polymerizable organic resin, a radiation activated initiator having an activation wavelength, an inert filler; and luminescent crystals, wherein the luminescent crystals emit radiation at a predetermined wavelength matching the initiator activation wavelength when the luminescent crystals are irradiated with radiation having a wavelength longer than the activation wavelength, the luminescent crystals being up-converting particles that result in those particles emitting radiation at a wavelength that initiates curing.

US Patent:

20220202658, Jun 30, 2022

Filed:

Apr 9, 2020

Appl. No.:

17/601786

Inventors:

- York PA, US
Joachim E. KLEE - Radolfzell, DE
Hui LU - Magnolia DE, US
Kira NEUHAUS - Dusseldorf, DE

Assignee:

DENTSPLY SIRONA Inc. - York PA

International Classification:

A61K 6/887
A61K 6/71
A61K 6/62
A61K 6/61

Abstract:

Disclosed herein is a dental material containing a polymerizable hydrolysis stable polycyclic amide monomer. The present disclosure relates to methods of making and use of the polymerizable hydrolysis stable polycyclic amide monomer for the preparation of a dental polymerizable hydrolysis stable polycyclic amide monomer composition. The present disclosure further relates to a cured dental material obtained by polymerizing the dental material.

US Patent:

20230022721, Jan 26, 2023

Filed:

Sep 9, 2022

Appl. No.:

17/941323

Inventors:

- York PA, US
Hui LU - Magnolia DE, US
Christopher DAMIEN - Marietta PA, US
Bernard KOLTISKO - Milton DE, US

Assignee:

DENTSPLY SIRONA Inc. - York PA

International Classification:

A01N 57/04
A61K 8/81
A61Q 11/00
A01N 33/12
A01N 57/34
A61K 8/55
A61K 8/898
A61K 8/41
A61K 6/20
A61K 6/887
A61B 42/10
A61B 46/00
A23L 33/16
A61C 5/70
A61C 5/50
A01N 25/08
A01N 25/10
A01N 43/50
A23L 2/52
A61B 17/06
A61B 17/84
A61B 17/86
A61C 7/08
A61C 7/16
A61C 8/00
A61C 9/00
A61C 13/00
A61C 19/06
A61F 2/00
A61F 2/06
A61F 2/16
A61F 2/24
A61F 6/04
A61F 6/08
A61F 6/14
A61F 13/20
A61F 13/36
A61M 5/14
A61M 16/00
A61M 25/00
A61M 27/00
F16L 58/04

Abstract:

Compositions and methods for inhibiting and interrupting biofilm formation, and for destabilizing established biofilms are provided, the novel compositions including polymeric resins and monomeric non-polymerizable and polymerizable resins. More particularly, the compositions and methods enable the protection and removal of biofilms from surfaces in the context of medical, consumer, domestic, food service, environmental and industrial applications, where the effects constitute beneficial and desirable biofilm attenuating activity.

US Patent:

20210275286, Sep 9, 2021

Filed:

May 24, 2021

Appl. No.:

17/328174

Inventors:

- York PA, US
Hui LU - Magnolia DE, US
Thomas ERTL - Ranstadt, DE

Assignee:

DENTSPLY SIRONA INC. - York PA

International Classification:

A61C 13/15
G01N 21/64
C09D 5/22
A61C 13/00
A61B 5/00
B33Y 10/00
B33Y 80/00
A61C 5/30
B33Y 30/00
A61C 5/70
A61C 5/77
B29C 64/129
A61C 13/09
A61K 6/25
A61K 6/30
A61K 6/40
A61K 6/70
A61K 6/78
A61K 6/822
A61K 6/824
A61K 6/838
A61K 6/887
A61C 7/14
A61C 7/16

Abstract:

A three-dimensional printing system including a feed source of uncured filled resin material, a print head configured to apply discrete layers of a composition including upconversion phosphors, and a radiation source configured to irradiate layers of uncured filled resin material and deposited layers of the composition is provided. A method of three dimensionally printing a dental article is also provided.