Dr. Yu graduated from the Bethune Med Univ, Changchun City, Jilin, China in 1986. She works in Mineola, NY and specializes in Neurology and Neuromuscular Medicine. Dr. Yu is affiliated with Winthrop University Hospital.
A method for producing T cells expressing a chimeric antigen receptor (CAR-T cells), comprising: (i) culturing CAR-T cells in a medium comprising lenalidomide or a derivative thereof to produce CAR-T cells, and optionally (ii) administering the CAR-T cells to a subject in need of the treatment.
- Zug, CH Demetrios Kalaitzidis - Cambridge MA, US Siyuan Tan - Cambridge MA, US Hui Yu - Cambridge MA, US
International Classification:
C12N 15/90 C12N 15/11 C12N 9/22 C12N 5/0783
Abstract:
Aspects of the present disclosure relate to methods for manufacturing genetically engineered T cells expressing a chimeric antigen receptor (CAR) that provide several improvements over conventional manufacturing methods, thereby enabling production of a robust supply of clinically useful CAR T-cell therapies.
Resumes
Senior Scientist, Immuno-Oncology Process Development
Crispr Therapeutics
Senior Scientist, Immuno-Oncology Process Development
Dana-Farber Cancer Institute Dec 1, 2015 - Apr 2017
Research Fellow
Boston Children's Hospital Oct 1, 2014 - Nov 2015
Research Fellow
St. Jude Children's Research Hospital Jun 2009 - Oct 2014
Research Assistant
Education:
The University of Tennessee Health Science Center 2008 - 2013
Doctorates, Doctor of Philosophy, Biology, Philosophy
Fudan University 2005 - 2008
Skills:
Cell Culture Western Blotting Cell Biology Flow Cytometry Molecular Cloning Confocal Microscopy Pcr Animal Models Tissue Culture Fluorescence Microscopy Immunofluorescence Research Rt Pcr Lifesciences Transfection Protein Expression Qpcr Gel Electrophoresis Immunoprecipitation Scientific Writing Human Ips Cells/Patient Derived Ips Cells Allogeneic Transplanation Intracerebroventricular Injection