Huiying Y Yang

US Patent:

6884590, Apr 26, 2005

Filed:

Oct 15, 1999

Appl. No.:

09/419408

Inventors:

Jerome I. Rotter - Los Angeles CA, US
Stephan R. Targan - Los Angeles CA, US
Huiying Yang - Cerritos CA, US
Arthur L. Beaudet - Houston TX, US
Devendra Vora - Torrance CA, US

Assignee:

Cedars-Sinai Medical Center - Los Angeles CA

International Classification:

G01N033/53

US Classification:

435 71, 435 6, 435 72, 5303871, 536 235

Abstract:

A novel association between IBD and a polymorphism at amino acid residue 241 of ICAM-1 has been discovered. In accordance with the present invention there is provided methods of screening for IBD, methods for treating IBD, antibodies specifically reactive with ICAM-1 encoded by, R241 allele and kits which exploit the inventive methods.

US Patent:

56816995, Oct 28, 1997

Filed:

Feb 11, 1994

Appl. No.:

8/196003

Inventors:

Jerome I. Rotter - Los Angeles CA
Stephan R. Targan - Los Angeles CA
Huiying Yang - Cerritos CA
Arthur L. Beaudet - Houston TX
Devendra Vora - Torrance CA

Assignee:

Cedars-Sinai Medical Center - Los Angeles CA

International Classification:

C12Q 168
C07H 2102
C07H 2104

US Classification:

435 6

Abstract:

A novel association between IBD and a polymorphism at amino acid residue 241 of ICAM-1 has been discovered. In accordance with the present invention there is provided methods of screening for IBD, methods for treating IBD, antibodies specifically reactive wish ICAM-1 encoded by R241 allele and kits which exploit the inventive methods.

US Patent:

60083352, Dec 28, 1999

Filed:

Sep 19, 1997

Appl. No.:

8/933824

Inventors:

Jerome I. Rotter - Los Angeles CA
Stephan R. Targan - Los Angeles CA
Huiying Yang - Cerritos CA
Arthur L. Beaudet - Houston TX
Devendra Vora - Torrance CA

Assignee:

Cedars-Sinai Medical Center - Los Angeles CA

International Classification:

C07H 2102
C07H 2104
C12Q 168

US Classification:

536 231

Abstract:

A novel association between IBD and a polymorphism at amino acid residue 241 of ICAM-1 has been discovered. In accordance with the present invention there is provided methods of screening for IBD, methods for treating IBD, antibodies specifically reactive with ICAM-1 encoded by R241 allele and kits which exploit the inventive methods.