Hye Eun Kim

US Patent:

20110165652, Jul 7, 2011

Filed:

Jan 14, 2009

Appl. No.:

12/812952

Inventors:

Susan H. Hardin - College Station TX, US
Norha Deluge - Pearland TX, US
Hongyi Wang - Pearland TX, US
Yuri Belosludtsev - The Woodlands TX, US
Kristi Kincaid - Houston TX, US
Anelia Kraltcheva - Houston TX, US
Benjamin Stevens - Philadelphia PA, US
Ming Fa - Pearland TX, US
Amy Bryant - Fredericksburg TX, US
Amy Castillo - Houston TX, US
Hye Eun Kim - Fort Worth TX, US
Uma Nagaswamy - Pearland TX, US
Mitsu Sreedhar Reddy - Pearland TX, US
Alok N. Bandekar - Pearland TX, US
Ivan Pan - Houston TX, US
Andrei Volkov - Houston TX, US

Assignee:

LIFE TECHNOLOGIES CORPORATION - Carlsbad CA

International Classification:

C12N 9/12

US Classification:

435194

Abstract:

Compositions, systems and methods of sequencing are disclosed, where the compositions and systems include polymerase enzymes that have been genetically modified to more efficiently incorporate nucleotides including labels having a detectable properties that are released during incorporation, to augment a rate of labeled nucleotide incorporation, to augment a rate of pyrophosphate release, or to augment two or more of these properties and rates. Also disclosed are terminally labeled and dual labeled nucleotides, and click-chemistry based methods of synthesizing the same.

Address:

8202 Pontiac Dr, Houston, TX 77096

VIN:

2T2GK31U67C012614

Make:

LEXUS

Model:

RX 350

Year:

2007