Ignacio J Pino

US Patent:

20140051586, Feb 20, 2014

Filed:

Jan 25, 2012

Appl. No.:

13/981308

Inventors:

Ignacio Pino - Mayaguez PR, US

International Classification:

G01N 33/543

US Classification:

506 2, 506 9, 506 18

Abstract:

Provided herein is a system and method for identifying a biomarker and producing a reagent for detecting the biomarker. The system and method comprises administering to an animal a biological sample and comparing the immune response of the animal to the immune response of another animal.

US Patent:

20130288910, Oct 31, 2013

Filed:

Jun 16, 2011

Appl. No.:

13/704592

Inventors:

Jef D. Boeke - Baltimore MD, US
Heng Zhu - Towson MD, US
Seth Blackshaw - Baltimore MD, US
Daniel J. Eichinger - Pleasantville NY, US
Ignacio Pino - Mayaguez PR, US

International Classification:

C07K 1/04

US Classification:

506 9, 506 18

Abstract:

Provided herein is a library of antibodies, wherein the library of antibodies can comprise a plurality of monoclonal, monospecific, or immunoprecipitating antibodies. Also provided herein is a method for producing and using the library of antibodies.

US Patent:

20190169689, Jun 6, 2019

Filed:

Aug 11, 2017

Appl. No.:

16/324836

Inventors:

- Mayaguez PR, US
Ignacio PINO - Mayaguez PR, US

International Classification:

C12Q 1/6876
C12Q 1/6834
C12Q 1/6869

Abstract:

This disclosure provides compositions and methods for analyzing a nucleic acid associated with an analyte.

US Patent:

20180030086, Feb 1, 2018

Filed:

Jun 23, 2017

Appl. No.:

15/632261

Inventors:

- MAYAGUEZ PR, US
- Baltimore MD, US
Seth BLACKSHAW - Baltimore MD, US
Daniel J. EICHINGER - Pleasantville NY, US
Ignacio PINO - Mayaguez PR, US

International Classification:

C07K 1/04
C07K 16/00
G01N 33/68

Abstract:

Provided herein is a library of antibodies, wherein the library of antibodies can comprise a plurality of monoclonal, monospecific, or immunoprecipitating antibodies. Also provided herein is a method for producing and using the library of antibodies.

US Patent:

20170212101, Jul 27, 2017

Filed:

Jul 17, 2015

Appl. No.:

15/326949

Inventors:

- Mayaguez PR, US
Jiang QIAN - Lutherville MD, US
Ignacio PINO - Mayaguez PR, US

Assignee:

CDI LABORATORIES, INC. - Mayaguez PR

International Classification:

G01N 33/53
C12N 15/10
G01N 33/543
C12Q 1/68

Abstract:

Proximity coupling and sequencing methods to screen, identify, validate and/or characterize interactions between analytes and binding moieties are disclosed. Also disclosed herein are proximity coupling methods and sequencing methods to determine or quantify levels of target analytes. The disclosed methods can be multiplexed in two dimensions, and can be used to determine the affinity and specificity of each of a plurality of binding moieties for each of a plurality of target analytes. Also disclosed herein are substrates, arrays, and reagents for use in the methods, and methods of their preparation.

US Patent:

20160060687, Mar 3, 2016

Filed:

Jul 17, 2015

Appl. No.:

14/802417

Inventors:

- Mayaguez PR, US
Jiang QIAN - Lutherville MD, US
Ignacio PINO - Mayaguez PR, US

International Classification:

C12Q 1/68

Abstract:

Proximity coupling and sequencing methods to screen identify, validate and/or characterize interactions between analytes and binding moieties are disclosed. Also disclosed herein are proximity coupling methods and sequencing methods to determine or quantify levels of target analytes. The disclosed methods can be multiplexed in two dimensions, and can be used to determine the affinity and specificity of each of a plurality of binding moieties for each of a plurality of target analytes. Also disclosed herein are substrates, arrays, and reagents for use in the methods, and methods of their preparation.