Ilya B Bezprozvanny

US Patent:

7829688, Nov 9, 2010

Filed:

Aug 12, 2008

Appl. No.:

12/190459

Inventors:

Mary Garry - Dallas TX, US
Ilya Bezprozvanny - Dallas TX, US

Assignee:

The Board of Regents of the University of Texas System - Austin TX

International Classification:

C07H 21/00
C40B 40/06

US Classification:

536 235, 506 16, 506 17, 536 234

Abstract:

The present invention relates to peptides of CaV2. 2 and their use in the treatment of pain. The sequence of the peptides is derived from the C-terminus of CaV2. 2. and is believed to inhibit the interaction of CaV2. 2 with Mint1-PDZ1. The invention is related to use of this peptide to treat pain and to use of this peptide in binding reaction with int-PDZ to screen for small molecules that can inhibit pain.

US Patent:

20050267036, Dec 1, 2005

Filed:

Mar 31, 2005

Appl. No.:

11/096281

Inventors:

Mary Garry - Dallas TX, US
Ilya Bezprozvanny - Dallas TX, US

International Classification:

A61K038/10
A61K038/08
A61K038/06
C07K007/06
C07K007/08

US Classification:

514016000, 514017000, 514018000, 530329000, 530330000

Abstract:

The present invention relates to peptides of CaV2.2 and their use in the treatment of pain. The sequence of the peptides is derived from the C-terminus of CaV2.2. and is believed to inhibit the interaction of CaV2.2 with Mint1-PDZ1. The invention is related to use of this peptide to treat pain and to use of this peptide in binding reaction with int-PDZ to screen for small molecules that can inhibit pain.

US Patent:

20160243098, Aug 25, 2016

Filed:

Feb 24, 2016

Appl. No.:

15/052368

Inventors:

Michal Geva - Even-Yehuda, IL
Ilya Bezprozvanny - Austin TX, US
Merav Bassan - Netanya, IL
Michael Hayden - Petach-Tikva, IL

Assignee:

Teva Pharmaceuticals International GmbH - Jona
The Board of Regents of The University of Texas System - Austin TX

International Classification:

A61K 31/451

Abstract:

This invention provides a method of improving cognitive function in a subject comprising periodically administering to the subject an amount of pridopidine or a pharmaceutically acceptable salt thereof effective to improve a cognitive function in the subject.The invention also provides a method of treating a subject afflicted with Alzheimer's disease, comprising periodically administering to the subject a pharmaceutical composition comprising an amount of pridopidine or a pharmaceutically acceptable salt thereof effective to treat the subject.