Ingrid K Nagy

US Patent:

49607995, Oct 2, 1990

Filed:

Apr 5, 1989

Appl. No.:

7/333772

Inventors:

Ingrid E. Nagy - Berkeley Heights NJ

Assignee:

Ciba-Geigy Corporation - Ardsley NY

International Classification:

A61K 31195

US Classification:

514567

Abstract:

Storage stable aqueous ophthalmic, substantially isotonic solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl) aminophenylacetic acid, and having a pH of about 7. 0 to about 7. 8, comprising per ml solution: (a) about 0. 1 to about 5. 0 mg of a pharmaceutically acceptable salt of ortho-(2,6-dichlorophenyl)aminophenylacetic acid; (b) about 0. 1 to about 10 mg of a pharmaceutically acceptable salt of ethylenediamine tetraacetic acid; (c) about 0. 5 to about 200 mg of a pharmaceutically acceptable solubilizer; (d) about 0. 01 to about 5. 0 mg of a pharmaceutically acceptable bacteriostat; and (e) the remainder water, and the use of such solutions, by topical administration to the eye of a warm blood mammal, for the control or treatment of ocular inflammation.