Innokenti I Toulokhonov from Fremont, CA, age 60

Methods To Identify Agents That Bind The Flap-Tip Helix Of Rna Polymerase
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US Patent:

20030003481, Jan 2, 2003
Filed:

Apr 23, 2002
Appl. No.:

10/128151
Inventors:

Robert Landick - Madison WI, US
Katherine Geszvain - Madison WI, US
Irina Artsimovitch - Worthington OH, US
Innokenti Toulokhonov - Madison WI, US
Rachel Mooney - Madison WI, US
International Classification:

C12Q001/68
G01N033/53
US Classification:

435/006000, 435/007100
Abstract:

The invention provides methods to identify moieties which specifically bind the flap-tip helix of the subunit of RNA polymerase and to identify inhibitors of the interaction between those moieties and the flap-tip helix.

Methods To Identify Agents That Bind The Flap-Tip Helix Of Rna Polymerase
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US Patent:

20080193921, Aug 14, 2008
Filed:

Apr 10, 2008
Appl. No.:

12/082329
Inventors:

Robert C. Landick - Madison WI, US
Irina E. Artsimovitch - Worthington OH, US
Innokenti I. Toulokhonov - Madison OH, US
Rachel A. Mooney - Madison WI, US
International Classification:

C12Q 1/70
C12Q 1/68
G01N 33/567
C12N 9/10
C12N 1/20
G01N 33/53
US Classification:

435 5, 435 6, 435 71, 435 72, 435243, 435193
Abstract:

The invention provides methods to identify moieties which specifically bind the flap-tip helix of the β subunit of RNA polymerase and to identify inhibitors of the interaction between those moieties and the flap-tip helix.

Innokenti I Toulokhonov