Irving R Weinberg

US Patent:

6545280, Apr 8, 2003

Filed:

Dec 8, 2000

Appl. No.:

09/733680

Inventors:

Irving Weinberg - Bethesda MD

Assignee:

PEM Technologies, Inc. - Bethesda MD

International Classification:

G01T 1161

US Classification:

25036302, 25036303, 378 37, 606131

Abstract:

A method for examining a body part is disclosed including the steps of immobilizing and compressing the body part to provide reproducible localization of an area of interest in the body part and to improve diagnostic quality of an image of the body part and obtaining at least one physiological image of the body part using multiple projection views of the body part. In an alternative embodiment a method of examining a body part is disclosed that includes the steps of injecting a patient with an agent whose concentration in the body part reflects the presence of malignant cells in the body part, said agent being a source of signal, immobilizing and compressing the body part to provide reproducible localization of an area of interest in the body part and to improve diagnostic quality of an image of the body part, placing a detector capable of detecting signals emitted by the agent in proximity to the body part; obtaining an image that displays the physiology of the body part based on signals emitted by the agent. In an alternative embodiment a method of examining a body part having tissue containing malignant cells is disclosed that includes the steps of injecting a patient with an agent whose concentration in the body part depends on the physiological processes in the body part, the agent being a source of signal, immobilizing and compressing the body part to provide reproducible localization of an area of interest in the body part and to improve diagnostic quality of an image of the body part, obtaining an internal anatomical image of the body part, placing a detector capable of detecting signals emitted by the agent in proximity to the body part and obtaining an image that displays the physiology of the body part based on signals emitted by the agent.

US Patent:

6555380, Apr 29, 2003

Filed:

Feb 15, 2001

Appl. No.:

09/784700

Inventors:

Irving N. Weinberg - Bethesda MD

Assignee:

PEM Technologies, Inc. - Rockville MD

International Classification:

G01N 2300

US Classification:

436 57, 436 63, 436 64, 436174

Abstract:

A system for describing the physical distribution of an agent that accumulates selectively in tissue of a patient in an excised surgical specimen. The system comprises an agent which selectively concentrates in a cancer or precancer or focus of infection or other pathological condition. The system comprises a detector sensitive to the agent which is present in the surgical specimen. The system also comprises an apparatus capable of forming an image based on the information gathered by the detector, and which image describes the physical distribution of the agent in the surgical specimen so that a surgeon can be guided by the image provided by the apparatus, the apparatus connected to said detector.

US Patent:

6628984, Sep 30, 2003

Filed:

Apr 11, 2001

Appl. No.:

09/833110

Inventors:

Irving N. Weinberg - Bethesda MD

Assignee:

PEM Technologies, Inc. - Bethesda MD

International Classification:

A61B 600

US Classification:

600436, 600407, 600425, 378 4, 25036302, 2503631, 25037009

Abstract:

A tomographic imaging system includes a moveable detector or detectors capable of detecting gamma radiation; one or more position sensors for determining the position and angulation of the detector(s) in relation to a gamma ray emitting source; and a computational device for integrating the position and angulation of the detector(s) with information as to the energy and distribution of gamma rays detected by the detector and deriving a three dimensional representation of the source based on the integration. A method of imaging a radiation emitting lesion located in a volume of interest also is disclosed.

US Patent:

6740882, May 25, 2004

Filed:

Oct 23, 2002

Appl. No.:

10/278096

Inventors:

Irving Weinberg - Bethesda MD

Assignee:

Naviscan PET Systems, Inc. - Rockville MD

International Classification:

G01T 1161

US Classification:

25036302, 25036303

Abstract:

The present invention is an apparatus for examining a body part. The apparatus comprises a mechanism for immobilizing and compressing the body part. The apparatus also comprises a mechanism for providing an internal anatomical image of the body part and a mechanism for detecting single gamma-rays emitted by a radiotracer infiltrated into the body part. The detecting mechanism is disposed in an adjacent relationship with the mechanism for providing an internal anatomic image so that the body part remains in the same position during and between anatomic and radiotracer imaging. In one embodiment, the detecting mechanism includes a detector module disposed on one side of the immobilizing mechanism. The detector module preferably has at least one array of gamma ray sensitive material in communication with a position detector. In another embodiment, the detecting mechanism includes a pair of detector modules disposed one on each side of the immobilizing mechanism.

US Patent:

7102134, Sep 5, 2006

Filed:

Feb 19, 2004

Appl. No.:

10/780584

Inventors:

Irving N. Weinberg - Bethesda MD, US

International Classification:

G01T 1/161

US Classification:

25036302

Abstract:

The present invention is an apparatus for examining a body part. The apparatus comprises a mechanism for immobilizing and compressing the body part. The apparatus also comprises a mechanism for providing an internal anatomical image of the body part and a mechanism for detecting single gamma-rays emitted by a radiotracer infiltrated into the body part. The detecting mechanism is disposed in an adjacent relationship with the mechanism for providing an internal anatomic image so that the body part remains in the same position during and between anatomic and radiotracer imaging. In one embodiment, the detecting mechanism includes a detector module disposed on one side of the immobilizing mechanism. The detector module preferably has at least one array of gamma ray sensitive material in communication with a position detector. In another embodiment, the detecting mechanism includes a pair of detector modules disposed one on each side of the immobilizing mechanism.

US Patent:

7115874, Oct 3, 2006

Filed:

Aug 11, 2003

Appl. No.:

10/637490

Inventors:

William Peter - Bethesda MD, US
Irving N. Weinberg - Bethesda MD, US
Stephen T. Yarnall - Poway CA, US

Assignee:

Naviscan PET Systems, Inc. - Rockville MD

International Classification:

G01T 1/164

US Classification:

25036303

Abstract:

A handheld gamma camera or PET system with a disposable detector head is provided. This system includes a configuration of a gamma camera or PET scanner in which optical fibers or bundles of optical fibers are coupled to a scintillator or array of scintillators and the other end of the optical fibers or bundles of optical fibers are coupled to a light-sensitive camera, such as a photomultiplier. The system may further include a mechanism to rapidly couple and/or decouple the optical fiber or fibers from the light sensitive camera or from the scintillator or array of scintillators so that the detector can be disposed of or sterilized without damaging the light-sensitive camera. A method for image reconstruction and image simulation is also provided. The method includes an application of deterministic sampling using Gaussian quadrature parameters to construct a transition matrix for purposes of image reconstruction.

US Patent:

7800070, Sep 21, 2010

Filed:

Apr 10, 2007

Appl. No.:

11/783613

Inventors:

Irving Weinberg - Bethesda MD, US
Valeri Saveliev - Hamburg, DE

Assignee:

Quantum Molecular Technologies, Inc. - Ontario

International Classification:

G01T 1/164
G01T 1/24

US Classification:

25036303, 25037006

Abstract:

A camera sub-module is provided for providing tomographic imaging of radiation emissions generated internally by a body. The camera sub-module includes a radiation-emitting layer having a radioactive source for emitting transmission emissions, and at least one radiation-detection layer for contemporaneously detecting and permitting differentiation between the transmission emissions and emissions generated internal to an imaged body administered with a positron-emitting radiotracer. Also provided herein are imaging systems, scanners, and other apparatus and methods.

US Patent:

7977643, Jul 12, 2011

Filed:

May 19, 2008

Appl. No.:

12/123412

Inventors:

Irving Weinberg - Bethesda MD, US

International Classification:

G01T 1/24

US Classification:

25037001

Abstract:

An assembly for detecting radiation is described. The assembly includes a host matrix with particles suspended within the host matrix. The particles are capable of generating a charge carrier upon interaction with the radiation. A first electrode is disposed adjacent to a first surface of the host matrix, and a second electrode disposed adjacent to a second surface of the host matrix. A power source operatively connects to one of the first or second electrodes. The power source establishes an electric field between the first and second electrodes such that a ratio of a mobility-lifetime-field strength product of the charge carrier to the thickness of the host matrix is greater than or equal to 0. 1. A radiation detector and a method for detecting radiation are also described.