Vanderbilt University Medical Center Neurosurgery 1500 21 Ave S STE 1506, Nashville, TN 37212 (615)3227417 (phone), (615)3227596 (fax)
Education:
Medical School Johns Hopkins University School of Medicine Graduated: 1999
Procedures:
Lumbar Puncture Carpal Tunnel Decompression Craniotomy Spinal Cord Surgery Spinal Fusion Spinal Surgery
Conditions:
Intervertebral Disc Degeneration Inguinal Hernia Intracranial Injury Malignant Neoplasm of Female Breast Overweight and Obesity
Languages:
English Spanish
Description:
Dr. Schwarz graduated from the Johns Hopkins University School of Medicine in 1999. He works in Nashville, TN and specializes in Surgery , Neurological. Dr. Schwarz is affiliated with Vanderbilt University Medical Center.
- La Jolla CA, US - South San Francisco CA, US Tucker Curran ROBERTS - San Diego CA, US Robert I. HIGUCHI - Solana Beach CA, US Prasuna PARASELLI - San Diego CA, US Michael F. T. KOEHLER - Palo Alto CA, US Jacob Bradley SCHWARZ - San Ramon CA, US James John CRAWFORD - San Francisco CA, US Cuong Q. LY - Burlingame CA, US Huiyong HU - Fremont CA, US Zhiyong YU - Shanghai, CN
International Classification:
C07K 7/06 A61P 31/04
Abstract:
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
- La Jolla CA, US - South San Francisco CA, US Robert I. HIGUCHI - Solana Beach CA, US Prasuna PARASELLI - San Diego CA, US Michael F. T. KOEHLER - Palo Alto CA, US Jacob Bradley SCHWARZ - San Ramon CA, US James John CRAWFORD - San Francisco CA, US Cuong Q. LY - Burlingame CA, US Emily J. HANAN - Redwood City CA, US Huiyong HU - Fremont CA, US Yongsheng CHEN - Shanghai, CN Zhiyong YU - Shanghai, CN Paul Colin Michael WINSHIP - Harlow, GB Calum McCleod - Harlow, GB Toby Blench - Harlow, GB
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
- La Jolla CA, US - South San Francisco CA, US Tucker Curran ROBERTS - San Diego CA, US Robert I. HIGUCHI - Solana Beach CA, US Prasuna PARASELLI - San Diego CA, US Michael F. T. KOEHLER - Palo Alto CA, US Jacob Bradley SCHWARZ - San Ramon CA, US James John CRAWFORD - San Francisco CA, US Cuong Q. LY - Burlingame CA, US Emily J. HANAN - Redwood City CA, US Huiyong HU - Fremont CA, US Zhiyong YU - Shanghai, CN
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
- La Jolla CA, US - San Francisco CA, US Robert I. HIGUCHI - Solana Beach CA, US Prasuna PARASELLI - San Diego CA, US Philippe BERGERON - Oakland CA, US Michael F.T. KOEHLER - Palo Alto CA, US Huiyong HU - Fremont CA, US Jacob Bradley SCHWARZ - San Ramon CA, US Cuong LY - Burlingame CA, US James CRAWFORD - San Francisco CA, US
Assignee:
RQX PHARMACEUTICALS, INC. - La Jolla CA GENENTECH, INC. - San Francisco CA
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
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