James Burgess

US Patent:

8293530, Oct 23, 2012

Filed:

Oct 17, 2007

Appl. No.:

11/873751

Inventors:

James E. Burgess - Gibsonia PA, US
Phil G. Campbell - Pittsburgh PA, US
Lee E. Weiss - Pittsburgh PA, US
Jason Smith - Pittsburgh PA, US

Assignee:

Carnegie Mellon University - Pittsburgh PA
Allegheny-Singer Research Institute - Pittsburgh PA

International Classification:

C12N 5/078

US Classification:

435372, 435 2

Abstract:

A method of making a bioplastic, and a bioplastic produced thereby, by using human plasma in which human plasma is clotted, either dried through its gel phase or dried and powdered, and processed into a bioplastic with the addition of at least one plasticizer followed by forming and heating to form a final bioplastic construct.

US Patent:

8529956, Sep 10, 2013

Filed:

Apr 17, 2008

Appl. No.:

12/104728

Inventors:

Phil G. Campbell - Cranberry Township PA, US
James E. Burgess - Gibsonia PA, US
Lee E. Weiss - Pittsburgh PA, US
Jason Smith - Pittsburgh PA, US

Assignee:

Carnell Therapeutics Corporation - Pittsburgh PA
Carnegie Mellon University - Pittsburgh PA
Allegheny-Singer Research Institute - Pittsburgh PA

International Classification:

A61K 35/16

US Classification:

424530, 424 937, 424 9372, 424422, 424423, 424489, 424499, 424520, 424529, 514 135, 514 136, 514 153, 435 2, 435372

Abstract:

Blood-derived plastic articles prepared from compositions including blood and, in some embodiments, at least one crosslinking agent and/or at least one biological response modifier, that can be useful for biological applications such as wound repair and tissue grafts; methods of making and using the same; methods for assessing the concentration of a biological response modifier in an article; and systems for preparing blood-derived plastic articles are provided.

US Patent:

8529958, Sep 10, 2013

Filed:

Jul 6, 2011

Appl. No.:

13/177029

Inventors:

Phil G. Campbell - Cranberry Township PA, US
James E. Burgess - Gibsonia PA, US
Lee E. Weiss - Pittsburgh PA, US
Jason Smith - Pittsburgh PA, US

Assignee:

Carmell Therapeutics Corporation - Pittsburgh PA
Allegheny-Singer Research Institute - Pittsburgh PA
Carnegie Mellon University - Pittsburgh PA

International Classification:

A61K 35/16

US Classification:

424530, 424 937, 424 9372, 424422, 424423, 424489, 424499, 424520, 424529, 514 135, 514 136, 514 153, 435 2, 435372

Abstract:

Blood-derived plastic articles prepared from compositions including blood and, in some embodiments, at least one crosslinking agent and/or at least one biological response modifier, that can be useful for biological applications such as wound repair and tissue grafts; methods of making and using the same; methods for assessing the concentration of a biological response modifier in an article; and systems for preparing blood-derived plastic articles are provided.

US Patent:

8529959, Sep 10, 2013

Filed:

Jul 6, 2011

Appl. No.:

13/177061

Inventors:

Phil G. Campbell - Cranberry Township PA, US
James E. Burgess - Gibsonia PA, US
Lee E. Weiss - Pittsburgh PA, US
Jason Smith - Pittsburgh PA, US

Assignee:

Carmell Therapeutics Corporation - Pittsburgh PA
Allegheny-Singer Research Institute - Pittsburgh PA
Carnegie Mellon University - Pittsburgh PA

International Classification:

A61K 35/16

US Classification:

424530, 424 937, 424 9372, 424422, 424423, 424489, 424499, 424520, 424529, 514 135, 514 136, 514 153, 435 2, 435372

Abstract:

Blood-derived plastic articles prepared from compositions including blood and, in some embodiments, at least one crosslinking agent and/or at least one biological response modifier, that can be useful for biological applications such as wound repair and tissue grafts; methods of making and using the same; methods for assessing the concentration of a biological response modifier in an article; and systems for preparing blood-derived plastic articles are provided.

US Patent:

8529960, Sep 10, 2013

Filed:

Jul 6, 2011

Appl. No.:

13/177090

Inventors:

Phil G. Campbell - Cranberry Township PA, US
James E. Burgess - Gibsonia PA, US
Lee E. Weiss - Pittsburgh PA, US
Jason Smith - Pittsburgh PA, US

Assignee:

Carnell Therapeutics Corporation - Pittsburgh PA
Allegheny-Singer Research Institute - Pittsburgh PA
Carnegie Mellon University - Pittsburgh PA

International Classification:

A61K 35/16

US Classification:

424530, 424 937, 424 9372, 424422, 424423, 424489, 424499, 424520, 424529, 514 135, 514 136, 514 153, 435 2, 435372

Abstract:

Blood-derived plastic articles prepared from compositions including blood and, in some embodiments, at least one crosslinking agent and/or at least one biological response modifier, that can be useful for biological applications such as wound repair and tissue grafts; methods of making and using the same; methods for assessing the concentration of a biological response modifier in an article; and systems for preparing blood-derived plastic articles are provided.

US Patent:

8529961, Sep 10, 2013

Filed:

Jul 6, 2011

Appl. No.:

13/177147

Inventors:

Phil G. Campbell - Cranberry Township PA, US
James E. Burgess - Gibsonia PA, US
Lee E. Weiss - Pittsburgh PA, US
Jason Smith - Pittsburgh PA, US

Assignee:

Carmell Therapeutics Corporation - Pittsburgh PA
Allegheny-Singer Research Institute - Pittsburgh PA
Carnegie Mellon University - Pittsburgh PA

International Classification:

A61K 35/16

US Classification:

424530, 424 937, 424 9372, 424422, 424423, 424489, 424499, 424520, 424529, 514 135, 514 136, 514 153, 435 2, 435372

Abstract:

Blood-derived plastic articles prepared from compositions including blood and, in some embodiments, at least one crosslinking agent and/or at least one biological response modifier, that can be useful for biological applications such as wound repair and tissue grafts; methods of making and using the same; methods for assessing the concentration of a biological response modifier in an article; and systems for preparing blood-derived plastic articles are provided.

US Patent:

20090036918, Feb 5, 2009

Filed:

Nov 13, 2007

Appl. No.:

11/939248

Inventors:

James E. Burgess - Gibsonia PA, US

International Classification:

A61B 17/00

US Classification:

606201

Abstract:

An apparatus for the containment of a surgical site includes an enclosure, with at least one port, securely coupled to the surgical site and a source of pressurized fluid in fluid communication with the enclosure via the at least one port providing pressurized fluid to the surgical site. The pressurized fluid establishes a hemostatic equilibrium within the enclosure by reducing blood egress through injuries in blood vessels at the surgical site thereby preventing bleeding at the surgical site. A method for the containment of a surgical site includes securely coupling an enclosure to a surgical site; fluidly coupling a source of pressurized fluid to the enclosure; and continuously providing pressurized fluid to the enclosure from the source of pressurized fluid and draining fluid from the enclosure. The pressurized fluid establishes a hemostatic equilibrium within the enclosure.

US Patent:

20120330271, Dec 27, 2012

Filed:

Feb 1, 2012

Appl. No.:

13/363482

Inventors:

James E. Burgess - Gibsonia PA, US

International Classification:

A61M 31/00

US Classification:

604500, 604 9301

Abstract:

An apparatus for the containment of a surgical site includes an enclosure, with at least one port, securely coupled to the surgical site and a source of pressurized fluid in fluid communication with the enclosure via the at least one port providing pressurized fluid to the surgical site. The pressurized fluid establishes a hemostatic equilibrium within the enclosure by reducing blood egress through injuries in blood vessels at the surgical site thereby preventing bleeding at the surgical site. A method for the containment of a surgical site includes securely coupling an enclosure to a surgical site; fluidly coupling a source of pressurized fluid to the enclosure; and continuously providing pressurized fluid to the enclosure from the source of pressurized fluid and draining fluid from the enclosure. The pressurized fluid establishes a hemostatic equilibrium within the enclosure.