- Vandalia OH, US Ken Kangyi QIAN - Cincinnati OH, US Shyam VANGALA - Huber Heights OH, US James M. CLEVENGER - Vandalia OH, US Donald GUENTHER - Brookville OH, US
International Classification:
A61K 9/20 A61K 31/4045
Abstract:
A tablet that rapidly disintegrates in the oral cavity comprising a compressed blend of rapidly dispersing microgranules prepared by granulating a sugar alcohol or a saccharide or a mixture thereof having an average particle size less than about 30 microns and a disintegrant, and a taste-masked microcapsule containing at least one drag, the microcapsule being prepared by granulating a pharmaceutically acceptable formulation comprising at least one drug in a therapeutically effective amount and at least one polymeric binder that improves resilience of the microgranules, wet milling the granulated mass, and microencapsulating the milled granules to provide microcapsules.
Orally Disintegrating Tablets And Methods Of Manufacture
- Vandalia OH, US Ken Kangyi Qian - Cincinnati OH, US Shyam Vangala - Huber Heights OH, US James M. Clevenger - Vandalia OH, US Donald Guenther - Brookville OH, US
International Classification:
A61K 9/20 A61K 31/4045 A61K 31/341
US Classification:
424465, 514471, 514415
Abstract:
A tablet that rapidly disintegrates in the oral cavity comprising a compressed blend of rapidly dispersing microgranules prepared by granulating a sugar alcohol or a saccharide or a mixture thereof having an average particle size less than about 30 microns and a disintegrant, and a taste-masked microcapsule containing at least one drug, the microcapsule being prepared by granulating a pharmaceutically acceptable formulation comprising at least one drug in a therapeutically effective amount and at least one polymeric binder that improves resilience of the microgranules, wet milling the granulated mass, and microencapsulating the milled granules to provide microcapsules.
Vincil James Clevenger, 87, Cameron, passed away on September 15, 2011 at Cameron Medical Center. Services: 3 pm Monday, September 19, at Poland-Thompson Chapel, Cameron. Visitation: 1 to 3 pm prior to services. Inurnment: at a later date at Wamsley ...