James R Mcdivitt

US Patent:

7513093, Apr 7, 2009

Filed:

Dec 13, 2005

Appl. No.:

11/301365

Inventors:

Howard Scalzo - Kenilworth NJ, US
Jerome A. Fischer - Warren NJ, US
Stephen Rothenburger - Neshanic Station NJ, US
Robert Cerwin - Pipersville PA, US
James R. McDivitt - Flemington NJ, US

Assignee:

Ethicon, Inc. - Somerville NJ

International Classification:

B65B 11/58
B65B 55/00

US Classification:

53449, 53425, 53167

Abstract:

A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.

US Patent:

8133437, Mar 13, 2012

Filed:

Dec 13, 2005

Appl. No.:

11/301364

Inventors:

Howard Scalzo - Kenilworth NJ, US
Jerome A. Fischer - Warren NJ, US
Stephen Rothenburger - Neshanic Station NJ, US
Robert Cerwin - Pipersville PA, US
James R. McDivitt - Flemington NJ, US

Assignee:

Ethicon, Inc. - Somerville NJ

International Classification:

A61L 9/00
A61L 2/00
A61L 2/18
A61L 2/20
B01J 7/00
B65B 11/58
A61B 17/06
A61L 17/00

US Classification:

422 29, 422 28, 422 33, 422292, 422294, 422305, 53449, 206 633, 606228

Abstract:

A method for making an antimicrobial suture comprising the steps of positioning an antimicrobial agent source within a package comprising an inner surface, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; positioning a medical device within the package; and subjecting the package, the antimicrobial agent source and the medical device to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the medical device, thereby substantially inhibiting bacterial colonization on the medical device. Alternatively, the packaged medical device is produced according to the steps of positioning a medical device within a package; exposing the package having the medical device to an antimicrobial agent source; and subjecting the package having the medical device and the antimicrobial agent source to time, temperature and pressure conditions sufficient to transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the medical device within the package, thereby substantially inhibiting bacterial colonization on the medical device.

US Patent:

8156718, Apr 17, 2012

Filed:

Apr 2, 2009

Appl. No.:

12/417518

Inventors:

Howard Scalzo - Kenilworth NJ, US
Jerome A. Fischer - Warren NJ, US
Stephen Rothenburger - Neshanic Station NJ, US
Robert Cerwin - Pipersville PA, US
James R. McDivitt - Flemington NJ, US

Assignee:

Ethicon, Inc. - Somerville NJ

International Classification:

B65B 55/02

US Classification:

53425, 53449, 206 633, 606228

Abstract:

A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.

US Patent:

20040068293, Apr 8, 2004

Filed:

Feb 15, 2003

Appl. No.:

10/367497

Inventors:

Howard Scalzo - Kenilworth NJ, US
Jerome Fischer - Warren NJ, US
James McDivitt - Flemington NJ, US
Stephen Rothenburger - Phillipsburg NJ, US
Robert Cerwin - Pipersville PA, US

International Classification:

A61B017/04

US Classification:

606/228000

Abstract:

An antimicrobial suture assembly comprising a containment compartment comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof, in an amount sufficient to substantially inhibit bacterial colonization on said containment compartment; and a suture positioned within the containment compartment, the suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof, in an amount sufficient to substantially inhibit bacterial colonization on the suture; and a method for making.

US Patent:

20120199502, Aug 9, 2012

Filed:

Apr 17, 2012

Appl. No.:

13/449184

Inventors:

Howard Scalzo - Kenilworth NJ, US
Jerome A. Fischer - Warren NJ, US
Stephen Rothenburger - Neshanic Station NJ, US
Robert Cerwin - Pipersville PA, US
James R. McDivitt - Flemington NJ, US

Assignee:

ETHICON, INC. - Somerville NJ

International Classification:

A61B 17/06
B65B 55/02

US Classification:

206 633, 53425

Abstract:

A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.

US Patent:

20120227360, Sep 13, 2012

Filed:

Mar 13, 2012

Appl. No.:

13/419377

Inventors:

Howard Scalzo - Kenilworth NJ, US
Jerome A. Fischer - Warren NJ, US
Stephen Rothenburger - Neshanic Station NJ, US
Robert Cerwin - Pipersville PA, US
James R. McDivitt - Flemington NJ, US

Assignee:

ETHICON, INC. - Somerville NJ

International Classification:

B65B 55/22

US Classification:

53431

Abstract:

A method for making an antimicrobial suture comprising the steps of positioning an antimicrobial agent source within a package comprising an inner surface, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; positioning a medical device within the package; and subjecting the package, the antimicrobial agent source and the medical device to time, temperature and pressure conditions sufficient to vapor transfer an effective amount of the antimicrobial agent from the antimicrobial agent source to the medical device, thereby substantially inhibiting bacterial colonization on the medical device.

US Patent:

20130193009, Aug 1, 2013

Filed:

Mar 13, 2013

Appl. No.:

13/802007

Inventors:

Jerome A. Fischer - Warren NJ, US
Stephen Rothenburger - Neshanic Station NJ, US
Robert Cerwin - Pipersville PA, US
James R. McDivitt - Flemington NJ, US

Assignee:

ETHICON, INC. - Somerville NJ

International Classification:

A61B 17/06

US Classification:

206206, 206205

Abstract:

A method of making a packaged antimicrobial suture comprising the steps of providing a containment compartment that is substantially free of an antimicrobial agent; positioning a suture within the containment compartment, said suture comprising one or more surfaces having an antimicrobial agent disposed thereon, said antimicrobial agent being selected from the group consisting of halogenated hydroxyl ethers, acyloxydiphenyl ethers, and combinations thereof; placing the containment compartment having the suture in an outer package; and subjecting the outer package, the containment compartment and the suture to time, temperature and pressure conditions sufficient to transfer an effective amount of the antimicrobial agent from the suture to the containment compartment, while retaining an effective amount of said antimicrobial agent on the suture, thereby substantially inhibiting bacterial colonization on the suture and the containment compartment.

US Patent:

6440364, Aug 27, 2002

Filed:

Feb 16, 1999

Appl. No.:

09/251244

Inventors:

Luis E. Vera - Bergenfield NJ
Robert J. Cerwin - Pipersville PA
LeRoy Hugo Anderson - San Angelo TX
Vincent Foerst - No. Plainfield NJ
John J. Karl - Hopatcong NJ
Lesley F. Traver - Branchburg NJ
James Richard McDivitt - Flemington NJ
Jimmy Dalton Webber - Cornelia GA

Assignee:

Ethicon, Inc. - Somerville NJ

International Classification:

A61L 900

US Classification:

422 33, 422 4, 422 28, 422 34, 422 36

Abstract:

A method of sterilizing absorbable sutures using a sterilant gas such as ethylene oxide gas. The method utilizes a first degassing step, and a second degassing step at elevated temperatures to remove residual sterilant gas, diluent gas, by-products and moisture.